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View Structure Prediction Details

Protein: gi|124126931, gi...
Organism: synthetic construct
Length: 566 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|124126931, gi....

Description E-value Query
Range
Subject
Range
gi|3021388 - gi|3021388|emb|CAA11530.1| CDC45 like protein [Homo sapiens]
0.0 [1..566] [1..566]
gi|30584643, gi|... - gi|60653115|gb|AAX29252.1| CDC45 cell division cycle 45-like [synthetic construct], gi|60653113|gb|A...
0.0 [1..566] [1..566]
gi|114685091 - gi|114685091|ref|XP_514980.2| PREDICTED: CDC45-like [Pan troglodytes]
0.0 [1..566] [1..566]
gi|109093266 - gi|109093266|ref|XP_001104872.1| PREDICTED: similar to CDC45-like [Macaca mulatta]
0.0 [1..566] [1..566]
gi|64174914 - gi|64174914|gb|AAY41172.1| DNA replication protein Cdc45 [Cricetulus griseus]
0.0 [1..566] [1..566]
gi|4185283, gi|6... - gi|6753366|ref|NP_033992.1| cell division cycle 45 homolog (S. cerevisiae)-like [Mus musculus], gi|4...
0.0 [1..566] [1..566]

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Predicted Domain #1
Region A:
Residues: [1-166]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFVSDFRKEF YEVVQSQRVL LFVASDVDAL CACKILQALF QCDHVQYTLV PVSGWQELET  60
   61 AFLEHKEQFH YFILINCGAN VDLLDILQPD EDTIFFVCDT HRPVNVVNVY NDTQIKLLIK 120
  121 QDDDLEVPAY EDIFRDEEED EEHSGNDSDG SEPSEKRTRL EEEIVE

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [167-252]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QTMRRRQRRE WEARRRDILF DYEQYEYHGT SSAMVMFELA WMLSKDLNDM LWWAIVGLTD  60
   61 QWVQDKITQM KYVTDVGVLQ RHVSRH

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.834 0.964 DNA replication initiation a.4.5 "Winged helix" DNA-binding domain

Predicted Domain #3
Region A:
Residues: [253-390]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NHRNEDEENT LSVDCTRISF EYDLRLVLYQ HWSLHDSLCN TSYTAARFKL WSVHGQKRLQ  60
   61 EFLADMGLPL KQVKQKFQAM DISLKENLRE MIEESANKFG MKDMRVQTFS IHFGFKHKFL 120
  121 ASDVVFATMS LMESPEKD

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.499 0.924 DNA replication initiation a.4.12 TrpR-like

Predicted Domain #4
Region A:
Residues: [391-566]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GSGTDHFIQA LDSLSRSNLD KLYHGLELAK KQLRATQQTI ASCLCTNLVI SQGPFLYCSL  60
   61 MEGTPDVMLF SRPASLSLLS KHLLKSFVCS TKNRRCKLLP LVMAAPLSME HGTVTVVGIP 120
  121 PETDSSDRKN FFGRAFEKAA ESTSSRMLHN HFDLSVIELK AEDRSKFLDA LISLLS

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle