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View Structure Prediction Details

Protein: gi|73947126
Organism: Canis lupus familiaris
Length: 207 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|73947126.

Description E-value Query
Range		 Subject
Range
LIN7B_RAT - Protein lin-7 homolog B OS=Rattus norvegicus GN=Lin7b PE=1 SV=1
 9.0E-45 [1..207] [1..207]
LIN7B_MOUSE - Protein lin-7 homolog B OS=Mus musculus GN=Lin7b PE=1 SV=2
 1.0E-44 [1..207] [1..207]
gi|109125456 - gi|109125456|ref|XP_001114636.1| PREDICTED: similar to lin-7 homolog B isoform 1 [Macaca mulatta]
 2.0E-43 [1..201] [1..201]
LIN7B_BOVIN - Protein lin-7 homolog B OS=Bos taurus GN=LIN7B PE=2 SV=1
 6.0E-43 [1..201] [1..201]
gi|73947124 - gi|73947124|ref|XP_533623.2| PREDICTED: similar to lin-7 homolog B isoform 1 [Canis familiaris]
 8.0E-42 [1..207] [1..225]
gi|114678227 - gi|114678227|ref|XP_001156271.1| PREDICTED: similar to Lin-7b [Pan troglodytes]
 5.0E-41 [6..207] [123..324]
gi|542167590|ref... - PREDICTED: protein lin-7 homolog C [Zonotrichia albicollis]
gi|224050405 - gi|224050405|ref|XP_002194172.1| PREDICTED: lin-7 homolog C [Taeniopygia guttata]
LIN7C_CHICK - Protein lin-7 homolog C OS=Gallus gallus GN=LIN7C PE=1 SV=1
 1.0E-39 [1..196] [1..196]
gi|62897873 - gi|62897873|dbj|BAD96876.1| lin-7 homolog C variant [Homo sapiens]
 2.0E-39 [1..196] [1..196]
gi|50882515, gi|... - gi|52219174|ref|NP_001004672.1| lin7c protein [Danio rerio], gi|51859336|gb|AAH81422.1| Lin-7 homolo...
 2.0E-39 [1..198] [1..198]

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Predicted Domain #1
Region A:
Residues: [1-88] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAALVEPLGL ERDVSRAVEL LERLQRSGEL PPQKLQALQR VLQSRFCSAI REVYEQLYDT  60
   61 LDITGSAEIR AHATAKATVA AFTASEGH

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 4.44
Match: 1y74A
Description: Solution Structure of mLin-2/mLin-7 L27 Domain Complex
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
epidermal growth factor receptor binding 2.83728577240611 bayes_pls_golite062009
binding 1.72922707266313 bayes_pls_golite062009
protein binding 1.08813585723961 bayes_pls_golite062009
PDZ domain binding 0.950044269901752 bayes_pls_golite062009
receptor binding 0.684990774885903 bayes_pls_golite062009
protein domain specific binding 0.450006870427269 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [89-207] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AHPRVVELPK TDEGLGFNIM GGKEQNSPIY ISRVIPGGVA DRHGGLKRGD QLLSVNGVSV  60
   61 EGEQHEKAVE LLKAAQGSVK LVVRYTPRVL EEMEARFEKM RSARRRQQHQ SYSSLESRG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 20.69897
Match: 2dkrA
Description: No description for 2dkrA was found.
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle