YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|67463796, gi\|...
Organism:	Plasmodium falciparum
Length:	173 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|67463796, gi|....

Description	E-value	Query Range	Subject Range
DUT_HAEI8 - Deoxyuridine 5'-triphosphate nucleotidohydrolase OS=Haemophilus influenzae (strain 86-028NP) GN=dut ... gi\|145274548, gi... - gi\|145640622\|ref\|ZP_01796205.1\| deoxyuridine 5'-triphosphate nucleotidohydrolase [Haemophilus influe... DUT_HAEIG - Deoxyuridine 5'-triphosphate nucleotidohydrolase OS=Haemophilus influenzae (strain PittGG) GN=dut PE... DUT_HAEIE - Deoxyuridine 5'-triphosphate nucleotidohydrolase OS=Haemophilus influenzae (strain PittEE) GN=dut PE... gi\|42631278 - gi\|42631278\|ref\|ZP_00156816.1\| COG0756: dUTPase [Haemophilus influenzae R2866] gi\|145640622 - gi\|145640622\|ref\|ZP_01796205.1\| deoxyuridine 5'-triphosphate nucleotidohydrolase [Haemophilus influe... DUT_HAEIN - Deoxyuridine 5'-triphosphate nucleotidohydrolase OS=Haemophilus influenzae (strain ATCC 51907 / DSM ... gi\|145272552, gi... - gi\|145638223\|ref\|ZP_01793833.1\| deoxyuridine 5'-triphosphate nucleotidohydrolase [Haemophilus influe... gi\|229811018, gi... - gi\|229846014\|ref\|ZP_04466126.1\| deoxyuridine 5'-triphosphate nucleotidohydrolase [Haemophilus influe... gi\|145269511, gi... - gi\|145637259\|ref\|ZP_01792920.1\| deoxyuridine 5'-triphosphate nucleotidohydrolase [Haemophilus influe... DUT_HAEIN - Deoxyuridine 5'-triphosphate nucleotidohydrolase OS=Haemophilus influenzae GN=dut PE=3 SV=1	163.0	[0..2]	[170..3]
gi\|50752967 - gi\|50752967\|ref\|XP_413814.1\| PREDICTED: similar to bumetanide-sensitive Na-K-Cl cotransport protein ...	162.0	[0..3]	[171..1469]
gi\|46129100 - gi\|46129100\|ref\|ZP_00155752.2\| COG0756: dUTPase [Haemophilus influenzae R2846]	160.0	[0..2]	[170..3]
gi\|114656884 - gi\|114656884\|ref\|XP_523069.2\| PREDICTED: dUTP pyrophosphatase isoform 6 [Pan troglodytes]	160.0	[0..1]	[171..112]
gi\|21956756, gi\|... - gi\|22124014\|ref\|NP_667437.1\| deoxyuridine 5'-triphosphate nucleotidohydrolase [Yersinia pestis KIM],... gi\|45439913, gi\|... - gi\|45439913\|ref\|NP_991452.1\| deoxyuridine 5'-triphosphate nucleotidohydrolase [Yersinia pestis biova...	160.0	[0..2]	[169..8]
gi\|77958458 - gi\|77958458\|ref\|ZP_00822491.1\| COG0756: dUTPase [Yersinia bercovieri ATCC 43970]	160.0	[0..2]	[169..4]
gi\|108813963, gi... - gi\|108813963\|ref\|YP_649730.1\| deoxyuridine 5'-triphosphate nucleotidohydrolase [Yersinia pestis Nepa... gi\|108809486, gi... - gi\|108809486\|ref\|YP_653402.1\| deoxyuridine 5'-triphosphate nucleotidohydrolase [Yersinia pestis Anti... gi\|145212794, gi... - gi\|145601098\|ref\|YP_001165174.1\| deoxyuridine 5'-triphosphate nucleotidohydrolase [Yersinia pestis P... gi\|89103897 - gi\|89103897\|ref\|ZP_01176457.1\| COG0756: dUTPase [Yersinia pestis biovar Orientalis str. IP275] gi\|77634074 - gi\|77634074\|ref\|ZP_00796183.1\| COG0756: dUTPase [Yersinia pestis Angola] gi\|170026364, gi... - gi\|170026364\|ref\|YP_001722869.1\| deoxyuridine 5'-triphosphate nucleotidohydrolase [Yersinia pseudotu... gi\|117671896, gi... - gi\|77630875\|ref\|ZP_00793461.1\| COG0756: dUTPase [Yersinia pseudotuberculosis IP 31758], gi\|117671896... gi\|186893390, gi... - gi\|186893390\|ref\|YP_001870502.1\| deoxyuridine 5'-triphosphate nucleotidohydrolase [Yersinia pseudotu...	160.0	[0..2]	[169..4]
gi\|165926111, gi... - gi\|165926111\|ref\|ZP_02221943.1\| deoxyuridine 5'-triphosphate nucleotidohydrolase [Yersinia pestis bi... gi\|229839896, gi... - gi\|229839896\|ref\|ZP_04460055.1\| deoxyuridinetriphosphatase [Yersinia pestis biovar Orientalis str. P... DUT_YERPG - Deoxyuridine 5'-triphosphate nucleotidohydrolase OS=Yersinia pestis bv. Antiqua (strain Angola) GN=d... gi\|229706607, gi... - gi\|229836159\|ref\|ZP_04456327.1\| deoxyuridinetriphosphatase [Yersinia pestis Pestoides A], gi\|2297066... gi\|115345879, gi... - gi\|218927268\|ref\|YP_002345143.1\| deoxyuridine 5'-triphosphate nucleotidohydrolase [Yersinia pestis C... gi\|229678611, gi... - gi\|229904493\|ref\|ZP_04519604.1\| deoxyuridinetriphosphatase [Yersinia pestis Nepal516], gi\|229678611\|... DUT_YERPE - Deoxyuridine 5'-triphosphate nucleotidohydrolase OS=Yersinia pestis GN=dut PE=3 SV=1 DUT_YERPS - Deoxyuridine 5'-triphosphate nucleotidohydrolase OS=Yersinia pseudotuberculosis serotype I (strain I... gi\|229690288, gi... - gi\|229841978\|ref\|ZP_04462133.1\| deoxyuridinetriphosphatase [Yersinia pestis biovar Orientalis str. I... gi\|167402097, gi... - gi\|167402097\|ref\|ZP_02307574.1\| deoxyuridine 5'-triphosphate nucleotidohydrolase [Yersinia pestis bi... gi\|166213714, gi... - gi\|166213714\|ref\|ZP_02239749.1\| deoxyuridine 5'-triphosphate nucleotidohydrolase [Yersinia pestis bi... gi\|166011436, gi... - gi\|166011436\|ref\|ZP_02232334.1\| deoxyuridine 5'-triphosphate nucleotidohydrolase [Yersinia pestis bi... gi\|165936135, gi... - gi\|165936135\|ref\|ZP_02224704.1\| deoxyuridine 5'-triphosphate nucleotidohydrolase [Yersinia pestis bi... gi\|150260889, gi... - gi\|150260889\|ref\|ZP_01917617.1\| deoxyuridine 5'-triphosphate nucleotidohydrolase [Yersinia pestis CA... DUT_YERP3 - Deoxyuridine 5'-triphosphate nucleotidohydrolase OS=Yersinia pseudotuberculosis serotype O:1b (strai... DUT_YERPS - Deoxyuridine 5'-triphosphate nucleotidohydrolase OS=Yersinia pseudotuberculosis GN=dut PE=3 SV=1 gi\|167054366, gi... - gi\|167426677\|ref\|ZP_02318430.1\| deoxyuridine 5'-triphosphate nucleotidohydrolase [Yersinia pestis bi... gi\|167419027, gi... - gi\|167419027\|ref\|ZP_02310780.1\| deoxyuridine 5'-triphosphate nucleotidohydrolase [Yersinia pestis bi...	160.0	[0..2]	[169..3]
gi\|109081025 - gi\|109081025\|ref\|XP_001113050.1\| PREDICTED: dUTP pyrophosphatase isoform 5 [Macaca mulatta]	159.0	[0..1]	[171..112]

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Predicted Domain #1

Region A:
Residues: [1-173]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MHLKIVCLSD EVREMYKNHK THHEGDSGLD LFIVKDEVLK PKSTTFVKLG IKAIALQYKS  60
   61 NYYYKCEKSE NKKKDDDKSN IVNTSFLLFP RSSISKTPLR LANSIGLIDA GYRGEIIAAL 120
  121 DNTSDQEYHI KKNDKLVQLV SFTGEPLSFE LVEELDETSR GEGGFGSTSN NKY

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	38.39794
Match:	1vyqA
Description:	Novel inhibitors of Plasmodium Falciparum dUTPase provide a platform for anti-malarial drug design
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits