YRC Public Data Repository - Protein Structure Prediction

Protein:	HIS52_CAMJR
Organism:	Campylobacter jejuni RM1221
Length:	195 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for HIS52_CAMJR.

Description	E-value	Query Range	Subject Range
gi\|87249768, gi\|... - gi\|87305308\|ref\|ZP_01087463.1\| imidazole glycerol phosphate synthase, glutamine amidotransferase sub...	167.0	[0..1]	[195..1]
gi\|86152240, gi\|... - gi\|86152240\|ref\|ZP_01070451.1\| imidazole glycerol phosphate synthase, glutamine amidotransferase sub... gi\|86152980, gi\|... - gi\|86152980\|ref\|ZP_01071185.1\| imidazole glycerol phosphate synthase, glutamine amidotransferase sub...	167.0	[0..1]	[195..1]
gi\|153951018, gi... - gi\|153951018\|ref\|YP_001398882.1\| imidazole glycerol phosphate synthase subunit HisH [Campylobacter j...	167.0	[0..1]	[195..1]
gi\|57242502, gi\|... - gi\|57242502\|ref\|ZP_00370440.1\| imidazole glycerol phosphate synthase, glutamine amidotransferase sub...	165.0	[0..1]	[191..1]
gi\|57504888, gi\|... - gi\|57504888\|ref\|ZP_00370863.1\| imidazole glycerol phosphate synthase, glutamine amidotransferase sub...	165.0	[0..1]	[194..1]
gi\|222823145, gi... - gi\|57241585\|ref\|ZP_00369530.1\| imidazole glycerol phosphate synthase, glutamine amidotransferase sub...	164.0	[0..1]	[193..1]
gi\|34398175 - gi\|34398175\|gb\|AAQ67177.1\| CAD [Empis sp. NCSU-99060925]	162.0	[0..2]	[194..131]
gi\|88931103, gi\|... - gi\|88931103\|ref\|ZP_01136797.1\| Glutamine amidotransferase of anthranilate synthase [Acidothermus cel...	162.0	[0..1]	[195..12]
gi\|34398189 - gi\|34398189\|gb\|AAQ67184.1\| CAD [Meghyperus sudeticus]	162.0	[0..2]	[194..133]
gi\|91184209, gi\|... - gi\|91217705\|ref\|ZP_01254662.1\| imidazole glycerol phosphate synthase subunit hisH [Psychroflexus tor...	162.0	[0..1]	[193..1]

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Predicted Domain #1

Region A:
Residues: [1-195]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKIIIIDTAC ANLASLKFCL DRLGFNATIS RDLKELESAD KLFLPGVGTA KEAMKNLEQF  60
   61 NLIDFIQNTK KPLLGICLGM QILGNFSEEL NQETLKLIDF TTQKFKAKEG FTFPHMGWNE 120
  121 VYSSHALFKG LEGAYFYFVH SYCVGLGKYT IADCEYSQKF SASVMKDNFY GVQFHPERSS 180
  181 EAGEILISNF IKDIG

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	29.09691
Match:	1jvnA
Description:	Cyclase subunit (or domain) of imidazoleglycerolphosphate synthase HisF; GAT subunit, HisH, (or domain) of imidazoleglycerolphosphate synthase HisF
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
imidazoleglycerol-phosphate synthase activity	8.34101262147614	bayes_pls_golite062009
ligase activity	1.70348758031146	bayes_pls_golite062009
catalytic activity	1.30391542469987	bayes_pls_golite062009
transferase activity, transferring pentosyl groups	0.643287540591989	bayes_pls_golite062009
ligase activity, forming carbon-nitrogen bonds	0.628648036096965	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: