YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|254243292, gi...
Organism:	Pseudomonas aeruginosa 2192
Length:	536 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|254243292, gi....

Description	E-value	Query Range	Subject Range
gi\|116053904, gi... - gi\|53726997\|ref\|ZP_00140606.2\| COG3119: Arylsulfatase A and related enzymes [Pseudomonas aeruginosa ...	0.0	[1..536]	[1..536]
gi\|17942716, gi\|... - gi\|17942717\|pdb\|1HDH\|B Chain B, Arylsulfatase From Pseudomonas Aeruginosa, gi\|17942716\|pdb\|1HDH\|A Ch...	0.0	[1..536]	[1..536]
gi\|94413548 - gi\|94413548\|ref\|ZP_01293429.1\| hypothetical protein PaerP_01004723 [Pseudomonas aeruginosa PA7]	0.0	[1..528]	[1..528]
gi\|84318424, gi\|... - gi\|84318424\|ref\|ZP_00966848.1\| COG3119: Arylsulfatase A and related enzymes [Pseudomonas aeruginosa ...	0.0	[1..536]	[1..533]
gi\|77380439, gi\|... - gi\|77456436\|ref\|YP_345941.1\| sulfatase [Pseudomonas fluorescens Pf0-1], gi\|77380439\|gb\|ABA71952.1\| a...	0.0	[1..533]	[1..533]
gi\|70733711, gi\|... - gi\|70733711\|ref\|YP_257351.1\| arylsulfatase [Pseudomonas fluorescens Pf-5], gi\|68348010\|gb\|AAY95616.1...	0.0	[1..533]	[1..533]
gi\|50084760, gi\|... - gi\|50084760\|ref\|YP_046270.1\| arylsulfatase (Aryl-sulfate sulphohydrolase) [Acinetobacter sp. ADP1], ...	0.0	[1..535]	[6..544]
gi\|66850995, gi\|... - gi\|70997211\|ref\|XP_753359.1\| arylsulfatase [Aspergillus fumigatus Af293], gi\|66850995\|gb\|EAL91321.1\|...	0.0	[1..528]	[42..593]
gi\|169779331 - gi\|169779331\|ref\|XP_001824130.1\| hypothetical protein [Aspergillus oryzae RIB40] gi\|83772869 - gi\|83772869\|dbj\|BAE62997.1\| unnamed protein product [Aspergillus oryzae]	0.0	[3..528]	[4..556]

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Predicted Domain #1

Region A:
Residues: [1-536]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSKRPNFLVI VADDLGFSDI GAFGGEIATP NLDALAIAGL RLTDFHTAST CSPTRSMLLT  60
   61 GTDHHIAGIG TMAEALTPEL EGKPGYEGHL NERVVALPEL LREAGYQTLM AGKWHLGLKP 120
  121 EQTPHARGFE RSFSLLPGAA NHYGFEPPYD ESTPRILKGT PALYVEDERY LDTLPEGFYS 180
  181 SDAFGDKLLQ YLKERDQSRP FFAYLPFSAP HWPLQAPREI VEKYRGRYDA GPEALRQERL 240
  241 ARLKELGLVE ADVEAHPVLA LTREWEALED EERAKSARAM EVYAAMVERM DWNIGRVVDY 300
  301 LRRQGELDNT FVLFMSDNGA EGALLEAFPK FGPDLLGFLD RHYDNSLENI GRANSYVWYG 360
  361 PRWAQAATAP SRLYKAFTTQ GGIRVPALVR YPRLSRQGAI SHAFATVMDV TPTLLDLAGV 420
  421 RHPGKRWRGR EIAEPRGRSW LGWLSGETEA AHDENTVTGW ELFGMRAIRQ GDWKAVYLPA 480
  481 PVGPATWQLY DLARDPGEIH DLADSQPGKL AELIEHWKRY VSETGVVEGA SPFLVR

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	136.0
Match:	1hdhA
Description:	Arylsulfatase B (4-sulfatase)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
sulfuric ester hydrolase activity	5.36665355899045	bayes_pls_golite062009
hydrolase activity	4.01787687283658	bayes_pls_golite062009
arylsulfatase activity	3.11969928063277	bayes_pls_golite062009
catalytic activity	2.31328968099128	bayes_pls_golite062009
hydrolase activity, acting on ester bonds	2.25924473866143	bayes_pls_golite062009
steryl-sulfatase activity	1.80539840111082	bayes_pls_golite062009
binding	1.41800746903495	bayes_pls_golite062009
phosphatase activity	0.659886528405157	bayes_pls_golite062009
phosphoric ester hydrolase activity	0.464622480235618	bayes_pls_golite062009
protein binding	0.208332656410563	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: