YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|73965638, gi\|...
Organism:	Canis lupus familiaris
Length:	254 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|73965638, gi|....

Description	E-value	Query Range	Subject Range
gi\|76688867 - gi\|76688867\|ref\|XP_869674.1\| PREDICTED: similar to amine oxidase, copper containing 2 isoform b isof...	439.0	[0..1]	[253..1]
PSME3_PONPY - Proteasome activator complex subunit 3 - Pongo pygmaeus (Orangutan) PSME3_PONAB - Proteasome activator complex subunit 3 OS=Pongo abelii GN=PSME3 PE=2 SV=1	394.0	[0..1]	[254..1]
gi\|54695640 - gi\|54695640\|gb\|AAV38192.1\| proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki) [syn...	393.0	[0..1]	[254..1]
gi\|49456449 - gi\|49456449\|emb\|CAG46545.1\| PSME3 [Homo sapiens]	392.0	[0..1]	[254..1]
gi\|73965644 - gi\|73965644\|ref\|XP_537633.2\| PREDICTED: similar to proteasome activator subunit 3 isoform 2 isoform ...	391.0	[0..1]	[254..1]
gi\|33086600 - gi\|33086600\|gb\|AAP92612.1\| Ab2-371 [Rattus norvegicus]	386.0	[0..1]	[253..1]
PSME3_CHICK - Proteasome activator complex subunit 3 OS=Gallus gallus GN=PSME3 PE=1 SV=1	385.0	[0..1]	[254..1]

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Predicted Domain #1

Region A:
Residues: [1-98]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MASLLKVDQE VKLKVDSFRE RITSEAEDLV ANFFPKKLLE LDSFLKEPIL NIHDLTQIHS  60
   61 DMNLPVPDPI LLTNSHDGLD GPTYKKRRLD ECEEAFQG

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	17.30103
Match:	1avoA
Description:	Proteasome activator reg(alpha)
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [99-254]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TKVFVMPNGM LKSNQQLVDI IEKVKPEIRL LIEKCNTVKM WVQLLIPRIE DGNNFGVSIQ  60
   61 EETVAELRTV ESEAASYLDQ ISRYYITRAK LVSKIAKYPH VEDYRRTVTE IDEKEYISLR 120
  121 LIISELRNQY VTLHDMILKN IEKIKRPRSS NAETLY

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	61.522879
Match:	1avoB
Description:	PROTEASOME ACTIVATOR REG(ALPHA)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
proteasome activator activity	5.59640159138257	bayes_pls_golite062009
proteasome regulator activity	4.54794772700869	bayes_pls_golite062009
binding	2.01347128874017	bayes_pls_golite062009
protein binding	0.834565661881528	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: