YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|75258074, gi\|...
Organism:	Escherichia coli E22
Length:	296 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|75258074, gi|....

Description	E-value	Query Range	Subject Range
METF_ERWCA - (P71319) 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) METF_PECCC - 5,10-methylenetetrahydrofolate reductase OS=Pectobacterium carotovorum subsp. carotovorum GN=metF PE...	404.0	[0..1]	[296..1]
gi\|50123164, gi\|... - gi\|50123164\|ref\|YP_052331.1\| 5,10-methylenetetrahydrofolate reductase [Pectobacterium atrosepticum S...	403.0	[0..1]	[296..1]
gi\|82546293, gi\|... - gi\|82546293\|ref\|YP_410240.1\| 5,10-methylenetetrahydrofolate reductase [Shigella boydii Sb227], gi\|81...	400.0	[0..1]	[296..1]
gi\|75765880, gi\|... - gi\|75765880\|pdb\|1ZRQ\|C Chain C, Escherichia Coli Methylenetetrahydrofolate Reductase (Reduced) Compl...	400.0	[0..1]	[296..1]
gi\|209401006, gi... - gi\|209401006\|ref\|YP_002273464.1\| 5,10-methylenetetrahydrofolate reductase [Escherichia coli O157:H7 ... gi\|217322146, gi... - gi\|217325925\|ref\|ZP_03442009.1\| 5,10-methylenetetrahydrofolate reductase [Escherichia coli O157:H7 s... gi\|195937592 - gi\|195937592\|ref\|ZP_03082974.1\| 5,10-methylenetetrahydrofolate reductase [Escherichia coli O157:H7 s... gi\|208809405, gi... - gi\|208809405\|ref\|ZP_03251742.1\| 5,10-methylenetetrahydrofolate reductase [Escherichia coli O157:H7 s... gi\|208812383, gi... - gi\|208812383\|ref\|ZP_03253712.1\| 5,10-methylenetetrahydrofolate reductase [Escherichia coli O157:H7 s... gi\|208740595, gi... - gi\|208820472\|ref\|ZP_03260792.1\| 5,10-methylenetetrahydrofolate reductase [Escherichia coli O157:H7 s... gi\|168775214, gi... - gi\|187769131\|gb\|EDU32975.1\| 5,10-methylenetetrahydrofolate reductase [Escherichia coli O157:H7 str. ... gi\|254795947, gi... - gi\|254795947\|ref\|YP_003080784.1\| 5,10-methylenetetrahydrofolate reductase [Escherichia coli O157:H7 ... gi\|168780869, gi... - gi\|189001450\|gb\|EDU70436.1\| 5,10-methylenetetrahydrofolate reductase [Escherichia coli O157:H7 str. ... gi\|13364346, gi\|... - gi\|15834124\|ref\|NP_312897.1\| 5,10-methylenetetrahydrofolate reductase [Escherichia coli O157:H7], gi... gi\|189373373, gi... - gi\|189373373\|gb\|EDU91789.1\| 5,10-methylenetetrahydrofolate reductase [Escherichia coli O157:H7 str. ... gi\|209752156, gi... - pir\|\|B86085 5,10-methylenetetrahydrofolate reductase [imported] - Escherichia coli (strain O157:H7, ... gi\|189378095, gi... - gi\|189378095\|gb\|EDU96511.1\| 5,10-methylenetetrahydrofolate reductase [Escherichia coli O157:H7 str. ... gi\|13364346, gi\|... - gi\|15834124\|ref\|NP_312897.1\| 5,10-methylenetetrahydrofolate reductase [Escherichia coli O157:H7 str.... gi\|188016841, gi... - gi\|188016841\|gb\|EDU54963.1\| 5,10-methylenetetrahydrofolate reductase [Escherichia coli O157:H7 str. ... gi\|15804538, gi\|... - gi\|15804538\|ref\|NP_290578.1\| 5,10-methylenetetrahydrofolate reductase [Escherichia coli O157:H7 EDL9... gi\|168755636, gi... - gi\|189357126\|gb\|EDU75545.1\| 5,10-methylenetetrahydrofolate reductase [Escherichia coli O157:H7 str. ... gi\|168761666, gi... - gi\|189367866\|gb\|EDU86282.1\| 5,10-methylenetetrahydrofolate reductase [Escherichia coli O157:H7 str. ... gi\|189362673, gi... - gi\|189362673\|gb\|EDU81092.1\| 5,10-methylenetetrahydrofolate reductase [Escherichia coli O157:H7 str. ...	399.0	[0..1]	[296..1]
gi\|81243012, gi\|... - gi\|82778864\|ref\|YP_405213.1\| 5,10-methylenetetrahydrofolate reductase [Shigella dysenteriae Sd197], ...	399.0	[0..1]	[296..1]
gi\|29139453, gi\|... - gi\|29143817\|ref\|NP_807159.1\| 5,10-methylenetetrahydrofolate reductase [Salmonella enterica subsp. en... gi\|224585920, gi... - gi\|224585920\|ref\|YP_002639719.1\| 5,10-methylenetetrahydrofolate reductase [Salmonella enterica subsp... gi\|213852568 - gi\|213852568\|ref\|ZP_03382100.1\| 5,10-methylenetetrahydrofolate reductase [Salmonella enterica subsp.... gi\|214003408 - gi\|214003408\|ref\|ZP_03414143.1\| 5,10-methylenetetrahydrofolate reductase [Salmonella enterica subsp.... gi\|213616085 - gi\|213616085\|ref\|ZP_03371911.1\| 5,10-methylenetetrahydrofolate reductase [Salmonella enterica subsp.... gi\|213648185 - gi\|213648185\|ref\|ZP_03378238.1\| 5,10-methylenetetrahydrofolate reductase [Salmonella enterica subsp.... gi\|213052149 - gi\|213052149\|ref\|ZP_03345027.1\| 5,10-methylenetetrahydrofolate reductase [Salmonella enterica subsp.... gi\|213427048 - gi\|213427048\|ref\|ZP_03359798.1\| 5,10-methylenetetrahydrofolate reductase [Salmonella enterica subsp.... gi\|197364878, gi... - gi\|197364878\|ref\|YP_002144515.1\| 5,10-methylenetetrahydrofolate reductase [Salmonella enterica subsp... gi\|204320753, gi... - gi\|204930349\|ref\|ZP_03221326.1\| 5,10-methylenetetrahydrofolate reductase [Salmonella enterica subsp.... gi\|205341831, gi... - gi\|205341831\|gb\|EDZ28595.1\| 5,10-methylenetetrahydrofolate reductase [Salmonella enterica subsp. ent... gi\|194710344, gi... - gi\|194734842\|ref\|YP_002117027.1\| 5,10-methylenetetrahydrofolate reductase [Salmonella enterica subsp... gi\|168262985, gi... - gi\|205348075\|gb\|EDZ34706.1\| 5,10-methylenetetrahydrofolate reductase [Salmonella enterica subsp. ent... gi\|168467455, gi... - gi\|195630149\|gb\|EDX48789.1\| 5,10-methylenetetrahydrofolate reductase [Salmonella enterica subsp. ent... gi\|161366610, gi... - gi\|161617246\|ref\|YP_001591211.1\| 5,10-methylenetetrahydrofolate reductase [Salmonella enterica subsp... gi\|168237734, gi... - gi\|197289383\|gb\|EDY28748.1\| 5,10-methylenetetrahydrofolate reductase [Salmonella enterica subsp. ent... gi\|62130200, gi\|... - gi\|62182567\|ref\|YP_218984.1\| 5,10-methylenetetrahydrofolate reductase [Salmonella enterica subsp. en... gi\|56415951, gi\|... - gi\|56415951\|ref\|YP_153026.1\| 5,10-methylenetetrahydrofolate reductase [Salmonella enterica subsp. en...	398.0	[0..1]	[296..1]
gi\|238912253 - gi\|238912253\|ref\|ZP_04656090.1\| 5,10-methylenetetrahydrofolate reductase [Salmonella enterica subsp.... lcl\|NC_016856.1_... - [gene=metF] [protein=5,10-methylenetetrahydrofolate reductase] [protein_id=YP_005240388.1] [location... gi\|205323684, gi... - gi\|205323684\|gb\|EDZ11523.1\| 5,10-methylenetetrahydrofolate reductase [Salmonella enterica subsp. ent... gi\|160866743, gi... - gi\|161505396\|ref\|YP_001572508.1\| 5,10-methylenetetrahydrofolate reductase [Salmonella enterica subsp... METF_SALTY - 5,10-methylenetetrahydrofolate reductase OS=Salmonella typhimurium GN=metF PE=3 SV=2 METF_SALTY - 5,10-methylenetetrahydrofolate reductase OS=Salmonella typhimurium GN=metF PE=3 SV=2 gi\|197241124, gi... - gi\|197262869\|ref\|ZP_03162943.1\| 5,10-methylenetetrahydrofolate reductase [Salmonella enterica subsp.... METF_SALTY - 5,10-methylenetetrahydrofolate reductase OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700... gi\|197251038, gi... - gi\|197251038\|ref\|YP_002149035.1\| 5,10-methylenetetrahydrofolate reductase [Salmonella enterica subsp... gi\|167991684, gi... - gi\|205330073\|gb\|EDZ16837.1\| 5,10-methylenetetrahydrofolate reductase [Salmonella enterica subsp. ent...	398.0	[0..1]	[296..1]
gi\|238712832, gi... - gi\|77956365\|ref\|ZP_00820470.1\| COG0685: 5,10-methylenetetrahydrofolate reductase [Yersinia bercovier...	397.0	[0..1]	[294..1]

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Predicted Domain #1

Region A:
Residues: [1-296]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSFFHASQRD ALNQSLAEVQ GQINVSFEFF PPRTSEMEQT LWNSIDRLSS LKPKFVSVTY  60
   61 GANSGERDRT HSIIKGIKDR TGLEAAPHLT CIDATPDELR TIARDYWNNG IRHIVALRGD 120
  121 LPPGSGKPEM YASDLVTLLK EVADFDISVA AYPEVHPEAK SAQADLLNLK RKVDAGANRA 180
  181 ITQFFFDVES YLRFRDRCVS AGIDVEIIPG ILPVSNFKQA KKFADMTNVR IPAWMAQMFD 240
  241 GLDDDAETRK LVGANIAMDM VKILSREGVK DFHFYTLNRA EMSYAICHTL GVRPGL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	112.0
Match:	1zp3A
Description:	E. coli Methylenetetrahydrofolate Reductase (oxidized)
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits