YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|85675448, gi\|...
Organism:	Escherichia coli str. K-12 substr. W3110
Length:	1295 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|85675448, gi|....

Description	E-value	Query Range	Subject Range
gi\|110616035, gi... - gi\|110806487\|ref\|YP_690007.1\| phosphoribosylformylglycinamidine synthase [Shigella flexneri 5 str. 8... gi\|24052983, gi\|... - ref\|NP_708394.1\| phosphoribosylformyl-glycineamide synthetase [Shigella flexneri 2a str. 301], gb\|A...	1442.0	[0..1]	[1295..53]
PUR4_SHISS - Phosphoribosylformylglycinamidine synthase OS=Shigella sonnei (strain Ss046) GN=purL PE=3 SV=3	1442.0	[0..1]	[1295..1]
gi\|187731888, gi... - gi\|75178152\|ref\|ZP_00698211.1\| COG0046: Phosphoribosylformylglycinamidine (FGAM) synthase, synthetas...	1441.0	[0..1]	[1295..1]
gi\|75211523, gi\|... - gi\|75211523\|ref\|ZP_00711613.1\| COG0046: Phosphoribosylformylglycinamidine (FGAM) synthase, synthetas...	1441.0	[0..1]	[1295..1]
gi\|194419617, gi... - gi\|83570782\|ref\|ZP_00922225.1\| COG0046: Phosphoribosylformylglycinamidine (FGAM) synthase, synthetas...	1441.0	[0..1]	[1295..1]
gi\|253772547, gi... - gi\|254289292\|ref\|YP_003055040.1\| phosphoribosylformylglycinamidine synthase [Escherichia coli BL21(D... gi\|194437694, gi... - gi\|194437694\|ref\|ZP_03069790.1\| phosphoribosylformylglycinamidine synthase [Escherichia coli 101-1],... gi\|253974432, gi... - gi\|254162531\|ref\|YP_003045639.1\| phosphoribosylformylglycinamidine synthase [Escherichia coli B str.... gi\|188488868, gi... - gi\|75515898\|ref\|ZP_00738033.1\| COG0046: Phosphoribosylformylglycinamidine (FGAM) synthase, synthetas...	1440.0	[0..1]	[1295..1]
PUR4_SHIBS - Phosphoribosylformylglycinamidine synthase OS=Shigella boydii serotype 4 (strain Sb227) GN=purL PE=3...	1440.0	[0..1]	[1295..1]
gi\|157077978, gi... - gi\|75187310\|ref\|ZP_00700577.1\| COG0046: Phosphoribosylformylglycinamidine (FGAM) synthase, synthetas...	1440.0	[0..1]	[1295..1]
gi\|217319728, gi... - gi\|217327361\|ref\|ZP_03443444.1\| phosphoribosylformylglycinamidine synthase [Escherichia coli O157:H7... gi\|208805865, gi... - gi\|208805865\|ref\|ZP_03248202.1\| phosphoribosylformylglycinamidine synthase [Escherichia coli O157:H7... gi\|208814009, gi... - gi\|208814009\|ref\|ZP_03255338.1\| phosphoribosylformylglycinamidine synthase [Escherichia coli O157:H7... gi\|208819723, gi... - gi\|208819723\|ref\|ZP_03260043.1\| phosphoribosylformylglycinamidine synthase [Escherichia coli O157:H7... gi\|209398316, gi... - gi\|209398316\|ref\|YP_002272031.1\| phosphoribosylformylglycinamidine synthase [Escherichia coli O157:H... gi\|189402491, gi... - gi\|189402491\|ref\|ZP_02782792.2\| phosphoribosylformylglycinamidine synthase [Escherichia coli O157:H7... gi\|189403144, gi... - gi\|189403144\|ref\|ZP_02793665.2\| phosphoribosylformylglycinamidine synthase [Escherichia coli O157:H7... gi\|189368436, gi... - gi\|189403949\|ref\|ZP_02786182.2\| phosphoribosylformylglycinamidine synthase [Escherichia coli O157:H7... gi\|195936704 - gi\|195936704\|ref\|ZP_03082086.1\| phosphoribosylformylglycinamidine synthase [Escherichia coli O157:H7... gi\|189378675, gi... - gi\|189378675\|gb\|EDU97091.1\| phosphoribosylformylglycinamidine synthase [Escherichia coli O157:H7 str... gi\|254593906, gi... - gi\|254794506\|ref\|YP_003079343.1\| phosphoribosylformyl-glycineamide synthetase [Escherichia coli O157... gi\|187775825, gi... - gi\|187775825\|ref\|ZP_02798527.2\| phosphoribosylformylglycinamidine synthase [Escherichia coli O157:H7... gi\|188024726, gi... - gi\|188024726\|ref\|ZP_02773398.2\| phosphoribosylformylglycinamidine synthase [Escherichia coli O157:H7... gi\|189009973, gi... - gi\|189009973\|ref\|ZP_02803538.2\| phosphoribosylformylglycinamidine synthase [Escherichia coli O157:H7... gi\|168787914, gi... - gi\|189372281\|gb\|EDU90697.1\| phosphoribosylformylglycinamidine synthase [Escherichia coli O157:H7 str... PUR4_ECO57 - Phosphoribosylformylglycinamidine synthase OS=Escherichia coli O157:H7 GN=purL PE=3 SV=3 gi\|25293856, gi\|... - pir\|\|G91056 phosphoribosylformyl-glycineamide synthetase [imported] - Escherichia coli (strain O157:... gi\|13362894, gi\|... - gi\|15832677\|ref\|NP_311450.1\| phosphoribosylformylglycinamidine synthase [Escherichia coli O157:H7 st...	1440.0	[0..1]	[1295..1]
gi\|56480135, gi\|... - gi\|56480135\|ref\|NP_708394.2\| phosphoribosylformylglycinamidine synthase [Shigella flexneri 2a str. 3... gi\|30042200, gi\|... - gi\|30063944\|ref\|NP_838115.1\| phosphoribosylformylglycinamidine synthase [Shigella flexneri 2a str. 2...	1440.0	[0..1]	[1295..1]

Back

Predicted Domain #1

Region A:
Residues: [1-1295]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MMEILRGSPA LSAFRINKLL ARFQAARLPV HNIYAEYVHF ADLNAPLNDD EHAQLERLLK  60
   61 YGPALASHAP QGKLLLVTPR PGTISPWSSK ATDIAHNCGL QQVNRLERGV AYYIEAGTLT 120
  121 NEQWQQVTAE LHDRMMETVF FALDDAEQLF AHHQPTPVTS VDLLGQGRQA LIDANLRLGL 180
  181 ALAEDEIDYL QDAFTKLGRN PNDIELYMFA QANSEHCRHK IFNADWVIDG EQQPKSLFKM 240
  241 IKNTFETTPD HVLSAYKDNA AVMEGSEVGR YFADHETGRY DFHQEPAHIL MKVETHNHPT 300
  301 AISPWPGAAT GSGGEIRDEG ATGRGAKPKA GLVGFSVSNL RIPGFEQPWE EDFGKPERIV 360
  361 TALDIMTEGP LGGAAFNNEF GRPALNGYFR TYEEKVNSHN GEELRGYHKP IMLAGGIGNI 420
  421 RADHVQKGEI NVGAKLVVLG GPAMNIGLGG GAASSMASGQ SDADLDFASV QRDNPEMERR 480
  481 CQEVIDRCWQ LGDANPILFI HDVGAGGLSN AMPELVSDGG RGGKFELREI LSDEPGMSPL 540
  541 EIWCNESQER YVLAVAADQL PLFDELCKRE RAPYAVIGEA TEELHLSLHD RHFDNQPIDL 600
  601 PLDVLLGKTP KMTRDVQTLK AKGDALAREG ITIADAVKRV LHLPTVAEKT FLVTIGDRSV 660
  661 TGMVARDQMV GPWQVPVANC AVTTASLDSY YGEAMAIGER APVALLDFAA SARLAVGEAL 720
  721 TNIAATQIGD IKRIKLSANW MAAAGHPGED AGLYEAVKAV GEELCPALGL TIPVGKDSMS 780
  781 MKTRWQEGNE EREMTSPLSL VISAFARVED VRHTITPQLS TEDNALLLID LGKGNNALGA 840
  841 TALAQVYRQL GDKPADVRDV AQLKGFYDAI QALVAQRKLL AYHDRSDGGL LVTLAEMAFA 900
  901 GHCGIDADIA TLGDDRLAAL FNEELGAVIQ VRAADREAVE SVLAQHGLAD CVHYVGQAVS 960
  961 GDRFVITANG QTVFSESRTT LRVWWAETTW QMQRLRDNPE CADQEHQAKS NDADPGLNVK1020
 1021 LSFDINEDVA APYIATGARP KVAVLREQGV NSHVEMAAAF HRAGFDAIDV HMSDLLTGRT1080
 1081 GLEDFHALVA CGGFSYGDVL GAGEGWAKSI LFNDRVRDEF ATFFHRPQTL ALGVCNGCQM1140
 1141 MSNLRELIPG SELWPRFVRN TSDRFEARFS LVEVTQSPSL LLQGMVGSQM PIAVSHGEGR1200
 1201 VEVRDAAHLA ALESKGLVAL RYVDNFGKVT ETYPANPNGS PNGITAVTTE SGRVTIMMPH1260
 1261 PERVFRTVSN SWHPENWGED GPWMRIFRNA RKQLG

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	1000.0
Match:	1t3tA
Description:	Structure of Formylglycinamide synthetase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
phosphoribosylformylglycinamidine cyclo-ligase activity	3.04322905277855	bayes_pls_golite062009
ligase activity, forming carbon-nitrogen bonds	2.97429034492683	bayes_pls_golite062009
catalytic activity	2.42746873085914	bayes_pls_golite062009
cyclo-ligase activity	2.40623349460413	bayes_pls_golite062009
phosphoribosylformylglycinamidine synthase activity	2.05243869055537	bayes_pls_golite062009
carbamoyl-phosphate synthase activity	1.74828881793189	bayes_pls_golite062009
carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity	1.74029540439985	bayes_pls_golite062009
ligase activity	1.57503501977169	bayes_pls_golite062009
carbon-nitrogen ligase activity, with glutamine as amido-N-donor	1.2570804600775	bayes_pls_golite062009
binding	1.25028632595227	bayes_pls_golite062009
transferase activity, transferring glycosyl groups	0.78656048097577	bayes_pls_golite062009
protein binding	0.277844441308003	bayes_pls_golite062009
nucleic acid binding	0.12569720972861	bayes_pls_golite062009
kinase activity	0.118160290398407	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: