YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|61360673, gi\|...
Organism:	synthetic construct
Length:	216 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|61360673, gi|....

Description	E-value	Query Range	Subject Range
gi\|30584767, gi\|... - gi\|61370407\|gb\|AAX43490.1\| fibroblast growth factor 19 [synthetic construct], gi\|30584767\|gb\|AAP3663...	3.0E-63	[1..216]	[1..216]
gi\|109105126 - gi\|109105126\|ref\|XP_001100825.1\| PREDICTED: fibroblast growth factor 19 [Macaca mulatta]	7.0E-63	[1..216]	[1..216]
gi\|76658281 - gi\|76658281\|ref\|XP_599739.2\| PREDICTED: similar to Fibroblast growth factor 19 precursor (FGF-19) [B...	8.0E-52	[1..214]	[225..440]
gi\|18389437, gi\|... - gi\|18543367\|ref\|NP_570109.1\| fibroblast growth factor 15 [Rattus norvegicus], gi\|18389437\|dbj\|BAB842...	1.0E-50	[3..216]	[6..218]
gi\|11643230, gi\|... - gi\|45382759\|ref\|NP_990005.1\| fibroblast growth factor 19 [Gallus gallus], gi\|11643230\|gb\|AAG39478.1\|...	1.0E-49	[23..216]	[26..227]
FGF15_MOUSE - Fibroblast growth factor 15 OS=Mus musculus GN=Fgf15 PE=2 SV=1	2.0E-49	[3..216]	[6..218]
gi\|1773016 - gi\|1773016\|emb\|CAA71365.1\| fibroblast growth factor 8 [Xenopus laevis]	8.0E-47	[1..200]	[1..195]
gi\|114306820 - gi\|114306820\|dbj\|BAF31291.1\| fibroblast growth factor 8a [Danio rerio]	3.0E-46	[1..204]	[1..198]

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Predicted Domain #1

Region A:
Residues: [1-216]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRSGCVVVHV WILAGLWLAV AGRPLAFSDA GPHVHYGWGD PIRLRHLYTS GPHGLSSCFL  60
   61 RIRADGVVDC ARGQSAHSLL EIKAVALRTV AIKGVHSVRY LCMGADGKMQ GLLQYSEEDC 120
  121 AFEEEIRPDG YNVYRSEKHR LPVSLSSAKQ RQLYKNRGFL PLSHFLPMLP MVPEEPEDLR 180
  181 GHLESDMFSS PLETDSMDPF GLVTGLEAVR SPSFEK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	56.522879
Match:	2p23A
Description:	No description for 2p23A was found.

Predicted functions:

Term	Confidence	Notes
growth factor activity	5.6790632853895	bayes_pls_golite062009
receptor binding	4.8109037277027	bayes_pls_golite062009
cytokine activity	3.06355212621053	bayes_pls_golite062009
protein binding	2.73885234721265	bayes_pls_golite062009
fibroblast growth factor receptor binding	2.46891559826707	bayes_pls_golite062009
binding	1.9997408351526	bayes_pls_golite062009
heparin binding	1.71092312487163	bayes_pls_golite062009
pattern binding	0.839280621598109	bayes_pls_golite062009
glycosaminoglycan binding	0.62267092567268	bayes_pls_golite062009
polysaccharide binding	0.55309369051712	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: