YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|75259172, gi\|...
Organism:	Escherichia coli E22
Length:	196 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|75259172, gi|....

Description	E-value	Query Range	Subject Range
gi\|119863969, gi... - gi\|119945365\|ref\|YP_943045.1\| imidazole glycerol phosphate synthase, glutamine amidotransferase subu...	192.0	[0..1]	[196..1]
gi\|77962463 - gi\|77962463\|ref\|ZP_00826283.1\| COG0118: Glutamine amidotransferase [Yersinia mollaretii ATCC 43969]	192.0	[0..1]	[196..1]
gi\|77975878 - gi\|77975878\|ref\|ZP_00831412.1\| COG0118: Glutamine amidotransferase [Yersinia frederiksenii ATCC 3364...	192.0	[0..1]	[196..1]
gi\|192955120, gi... - gi\|75214869\|ref\|ZP_00713350.1\| COG0118: Glutamine amidotransferase [Escherichia coli E110019], gi\|19... gi\|194428759, gi... - gi\|75210033\|ref\|ZP_00710216.1\| COG0118: Glutamine amidotransferase [Escherichia coli B171], gi\|19442...	192.0	[0..1]	[196..1]
gi\|77959283 - gi\|77959283\|ref\|ZP_00823304.1\| COG0118: Glutamine amidotransferase [Yersinia bercovieri ATCC 43970]	191.0	[0..1]	[196..1]
gi\|77978865 - gi\|77978865\|ref\|ZP_00834289.1\| COG0118: Glutamine amidotransferase [Yersinia intermedia ATCC 29909]	190.0	[0..1]	[196..1]
HIS5_SHIFL - Imidazole glycerol phosphate synthase subunit HisH OS=Shigella flexneri GN=hisH PE=3 SV=1 gi\|24052430, gi\|... - gi\|24113408\|ref\|NP_707918.1\| imidazole glycerol phosphate synthase subunit HisH [Shigella flexneri 2... gi\|110615544, gi... - gi\|110805996\|ref\|YP_689516.1\| imidazole glycerol phosphate synthase subunit HisH [Shigella flexneri ... gi\|30063473, gi\|... - gi\|30063473\|ref\|NP_837644.1\| imidazole glycerol phosphate synthase subunit HisH [Shigella flexneri 2...	190.0	[0..1]	[196..1]
HIS5_SALPA - Imidazole glycerol phosphate synthase subunit HisH OS=Salmonella paratyphi A (strain ATCC 9150 / SAR... HIS5_SALPA - Imidazole glycerol phosphate synthase subunit HisH OS=Salmonella paratyphi A GN=hisH PE=3 SV=1 HIS5_SALCH - Imidazole glycerol phosphate synthase subunit hisH OS=Salmonella choleraesuis GN=hisH PE=3 SV=2 HIS5_SALTY - Imidazole glycerol phosphate synthase subunit HisH OS=Salmonella typhimurium GN=hisH PE=3 SV=1 HIS5_SALCH - Imidazole glycerol phosphate synthase subunit HisH OS=Salmonella choleraesuis GN=hisH PE=3 SV=2 gi\|197263884, gi... - gi\|197263884\|ref\|ZP_03163958.1\| imidazole glycerol phosphate synthase, glutamine amidotransferase su... gi\|194738319, gi... - gi\|194738319\|ref\|YP_002115162.1\| imidazole glycerol phosphate synthase, glutamine amidotransferase s... gi\|194472955, gi... - gi\|194472955\|ref\|ZP_03078939.1\| imidazole glycerol phosphate synthase, glutamine amidotransferase su... gi\|194447980, gi... - gi\|194447980\|ref\|YP_002046125.1\| imidazole glycerol phosphate synthase subunit HisH [Salmonella ente... gi\|204321513, gi... - gi\|204928969\|ref\|ZP_03220112.1\| imidazole glycerol phosphate synthase, glutamine amidotransferase su... gi\|199605427, gi... - gi\|200388329\|ref\|ZP_03214941.1\| imidazole glycerol phosphate synthase, glutamine amidotransferase su... gi\|197937908, gi... - gi\|198243392\|ref\|YP_002216161.1\| imidazole glycerol phosphate synthase, glutamine amidotransferase s... gi\|197093427, gi... - gi\|197361950\|ref\|YP_002141587.1\| imidazole glycerol phosphate synthase subunit HisH [Salmonella ente... HIS5_SALTY - Imidazole glycerol phosphate synthase subunit hisH OS=Salmonella typhimurium GN=hisH PE=3 SV=1 gi\|168236227, gi... - gi\|197290515\|gb\|EDY29870.1\| imidazole glycerol phosphate synthase, glutamine amidotransferase subuni... gi\|168229394, gi... - gi\|205335634\|gb\|EDZ22398.1\| imidazole glycerol phosphate synthase, glutamine amidotransferase subuni... gi\|167990989, gi... - gi\|205330592\|gb\|EDZ17356.1\| imidazole glycerol phosphate synthase, glutamine amidotransferase subuni... HIS5_SALTY - Imidazole glycerol phosphate synthase subunit HisH OS=Salmonella typhimurium (strain LT2 / SGSC1412 ... gi\|161362612, gi... - gi\|161613248\|ref\|YP_001587213.1\| imidazole glycerol phosphate synthase subunit HisH [Salmonella ente... HIS5_SALCH - Imidazole glycerol phosphate synthase subunit HisH OS=Salmonella choleraesuis (strain SC-B67) GN=his... gi\|194443517, gi... - gi\|194443517\|ref\|YP_002041343.1\| imidazole glycerol phosphate synthase, glutamine amidotransferase s... gi\|168818233, gi... - gi\|205345002\|gb\|EDZ31766.1\| imidazole glycerol phosphate synthase, glutamine amidotransferase subuni... gi\|205351156, gi... - gi\|205351156\|gb\|EDZ37787.1\| imidazole glycerol phosphate synthase, glutamine amidotransferase subuni... gi\|168242147, gi... - gi\|205338562\|gb\|EDZ25326.1\| imidazole glycerol phosphate synthase, glutamine amidotransferase subuni... gi\|16761006 - gi\|16761006\|ref\|NP_456623.1\| imidazole glycerol phosphate synthase subunit HisH [Salmonella enterica... gi\|213648076 - gi\|213648076\|ref\|ZP_03378129.1\| imidazole glycerol phosphate synthase subunit HisH [Salmonella enter... gi\|213622708 - gi\|213622708\|ref\|ZP_03375491.1\| imidazole glycerol phosphate synthase subunit HisH [Salmonella enter... gi\|213425566 - gi\|213425566\|ref\|ZP_03358316.1\| imidazole glycerol phosphate synthase subunit HisH [Salmonella enter... gi\|213161019 - gi\|213161019\|ref\|ZP_03346729.1\| imidazole glycerol phosphate synthase subunit HisH [Salmonella enter... gi\|224583428, gi... - gi\|224583428\|ref\|YP_002637226.1\| imidazole glycerol phosphate synthase subunit HisH [Salmonella ente... gi\|214001358 - gi\|214001358\|ref\|ZP_03412093.1\| imidazole glycerol phosphate synthase subunit HisH [Salmonella enter... gi\|213859453 - gi\|213859453\|ref\|ZP_03385157.1\| imidazole glycerol phosphate synthase subunit HisH [Salmonella enter... gi\|238913443 - gi\|238913443\|ref\|ZP_04657280.1\| imidazole glycerol phosphate synthase subunit HisH [Salmonella enter... lcl\|NC_016856.1_... - [gene=hisH] [protein=imidazole glycerol phosphate synthase subunit HisH] [protein_id=YP_005238110.2]... HIS5_SALTI - Imidazole glycerol phosphate synthase subunit HisH OS=Salmonella typhi GN=hisH PE=3 SV=1 gi\|29136924, gi\|... - gi\|29141298\|ref\|NP_804640.1\| imidazole glycerol phosphate synthase subunit HisH [Salmonella enterica... HIS5_SALTI - Imidazole glycerol phosphate synthase subunit hisH OS=Salmonella typhi GN=hisH PE=3 SV=1	189.0	[0..1]	[196..1]
gi\|85059104, gi\|... - gi\|85059104\|ref\|YP_454806.1\| imidazole glycerol phosphate synthase subunit HisH [Sodalis glossinidiu...	189.0	[0..1]	[196..1]
HIS5_VIBF1 - Imidazole glycerol phosphate synthase subunit HisH OS=Vibrio fischeri (strain ATCC 700601 / ES114) G...	189.0	[0..2]	[196..5]

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Predicted Domain #1

Region A:
Residues: [1-196]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNVVILDTGC ANLNSVKSAI ARHGYEPKVS RDPDVVLLAD KLFLPGVGTA QAAMDQVRER  60
   61 ELFDLIKACT QPVLGICLGM QLLGRRSEES NGVDLLGIID EDVPKMTDFG LPLPHMGWNR 120
  121 VYPQAGNRLF QGIEDGAYFY FVHSYAMPVN PWTIAQCNYG EPFTAAVQKD NFYGVQFHPE 180
  181 RSGAAGAKLL KNFLEM

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	34.522879
Match:	1jvnA
Description:	Cyclase subunit (or domain) of imidazoleglycerolphosphate synthase HisF; GAT subunit, HisH, (or domain) of imidazoleglycerolphosphate synthase HisF
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
imidazoleglycerol-phosphate synthase activity	8.34101262147614	bayes_pls_golite062009
ligase activity	1.70348758031146	bayes_pls_golite062009
catalytic activity	1.30391542469987	bayes_pls_golite062009
transferase activity, transferring pentosyl groups	0.643287540591989	bayes_pls_golite062009
ligase activity, forming carbon-nitrogen bonds	0.628648036096965	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: