YRC Public Data Repository - Protein Structure Prediction

Protein:	TIM10_NEUCR
Organism:	Neurospora crassa OR74A
Length:	90 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TIM10_NEUCR.

Description	E-value	Query Range	Subject Range
gi\|73955150 - gi\|73955150\|ref\|XP_854099.1\| PREDICTED: similar to Mitochondrial import inner membrane translocase s...	103.0	[0..1]	[85..166]
gi\|50766075 - gi\|50766075\|ref\|XP_422986.1\| PREDICTED: similar to translocase of inner mitochondrial membrane 10 ho...	98.0	[0..14]	[89..124]
gi\|87248623, gi\|... - gi\|87248623\|gb\|ABD36364.1\| mitochondrial intermembrane space translocase subunit Tim10 [Bombyx mori]...	96.0	[0..4]	[83..1]
TIM10_YARLI - Mitochondrial import inner membrane translocase subunit TIM10 OS=Yarrowia lipolytica (strain CLIB 12... TIM10_YARLI - Mitochondrial import inner membrane translocase subunit TIM10 OS=Yarrowia lipolytica GN=TIM10 PE=3 S...	96.0	[0..3]	[90..8]
TIM10_ASHGO - Mitochondrial import inner membrane translocase subunit TIM10 OS=Ashbya gossypii GN=TIM10 PE=3 SV=1 TIM10_ASHGO - Mitochondrial import inner membrane translocase subunit TIM10 OS=Ashbya gossypii (strain ATCC 10895 ...	94.0	[0..1]	[88..1]
gi\|114195880, gi... - gi\|115388581\|ref\|XP_001211796.1\| mitochondrial import inner membrane translocase subunit tim10 [Aspe...	94.0	[0..5]	[90..7]
TIM10_ASPFU - Mitochondrial import inner membrane translocase subunit tim10 OS=Aspergillus fumigatus GN=tim10 PE=3... TIM10_ASPFU - Mitochondrial import inner membrane translocase subunit tim10 OS=Neosartorya fumigata (strain ATCC M... gi\|159130673 - gi\|159130673\|gb\|EDP55786.1\| mitochondrial intermembrane space translocase subunit Tim10, putative [A... gi\|119496885, gi... - gi\|119496885\|ref\|XP_001265216.1\| mitochondrial intermembrane space translocase subunit Tim10, putati...	94.0	[0..5]	[90..7]
TIM10_KLULA - Mitochondrial import inner membrane translocase subunit TIM10 OS=Kluyveromyces lactis (strain ATCC 8... TIM10_KLULA - Mitochondrial import inner membrane translocase subunit TIM10 OS=Kluyveromyces lactis GN=TIM10 PE=3 ...	92.0	[0..1]	[88..1]
gi\|114690216 - gi\|114690216\|ref\|XP_001134944.1\| PREDICTED: similar to small zinc finger-like protein [Pan troglodyt...	92.0	[0..2]	[85..35]
TIM8B_MOUSE - Mitochondrial import inner membrane translocase subunit Tim8 B OS=Mus musculus GN=Timm8b PE=1 SV=1 TIM8B_RAT - Mitochondrial import inner membrane translocase subunit Tim8 B OS=Rattus norvegicus GN=Timm8b PE=3 S...	91.0	[0..1]	[85..1]

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Predicted Domain #1

Region A:
Residues: [1-90]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFGLGRPQPT SAEKIAAVEN ELKVVAEMHS RMVKICTLKC IDKSYREGDL SKGESVCLDR  60
   61 CAAKFFETHQ KISDQLQKET QARGGGGFGM

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	16.522879
Match:	2bskB
Description:	Crystal structure of the TIM9 Tim10 hexameric complex
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
protein transporter activity	3.96569591038426	bayes_pls_golite062009
transporter activity	3.42555440535265	bayes_pls_golite062009
protein transmembrane transporter activity	3.05578860381335	bayes_pls_golite062009
P-P-bond-hydrolysis-driven protein transmembrane transporter activity	2.52072322460318	bayes_pls_golite062009
macromolecule transmembrane transporter activity	2.52072322460318	bayes_pls_golite062009
binding	2.38169553639759	bayes_pls_golite062009
substrate-specific transporter activity	2.26454691978513	bayes_pls_golite062009
transmembrane transporter activity	2.01475009173074	bayes_pls_golite062009
protein binding	1.54231655177329	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	1.5410808613005	bayes_pls_golite062009
unfolded protein binding	0.0997632819038001	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: