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View Structure Prediction Details

Protein: Hsf-PC
Organism: Drosophila melanogaster
Length: 709 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Hsf-PC.

Description E-value Query
Range
Subject
Range
Hsf-PD - The gene Heat shock factor is referred to in FlyBase by the symbol Dmel\Hsf (CG5748, FBgn0001222). I...
478.0 [0..1] [709..1]

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Predicted Domain #1
Region A:
Residues: [1-148]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSRSRSSAKA VQFKHESEEE EEDEEEQLPS RRMHSYGDAA AIGSGVPAFL AKLWRLVDDA  60
   61 DTNRLICWTK DGQSFVIQNQ AQFAKELLPL NYKHNNMASF IRQLNMYGFH KITSIDNGGL 120
  121 RFDRDEIEFS HPFFKRNSPF LLDQIKRK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 40.69897
Match: 1hksA
Description: SOLUTION STRUCTURE OF THE DNA-BINDING DOMAIN OF DROSOPHILA HEAT SHOCK TRANSCRIPTION FACTOR
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
nucleic acid binding 4.99681957904233 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [149-244]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ISNNKNGDDK GVLKPEAMSK ILTDVKVMRG RQDNLDSRFS AMKQENEVLW REIASLRQKH  60
   61 AKQQQIVNKL IQFLITIVQP SRNMSGVKRH VQLMIN

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 10.102373
Match: PF00447.8
Description: No description for PF00447.8 was found.

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [245-460]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NTPEIDRART TSETESESGG GPVIHELREE LLDEVMNPSP AGYTAASHYD QESVSPPAVE  60
   61 RPRSNMSISS HNVDYSNQSV EDLLLQGNGT AGGNILVGGA ASPMAQSVSQ SPAQHDVYTV 120
  121 TEAPDSHVQE VPNSPPYYEE QNVLTTPMVR EQEQQKRQQL KENNKLRRQA GDVILDAGDI 180
  181 LVDSSSPKAQ RTSIQHSTQP DVMVQPMIIK SEPENS

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [461-572]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SGLMDLMTPA NDLYSVNFIS EDMPTDIFED ALLPDGVEEA AKLDQQQKFG QSTVSSGKFA  60
   61 SNFDVPTNST LLDANQASTS KAAAKAQASE EEGMAVAKYS GAENGNNRDT NN

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [573-709]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SQLLRMASVD ELHGHLESMQ DELETLKDLL RGDGVAIDQN MLMGALSRTP NFQLPEDELL  60
   61 LKLFNDSDLM DNYGLSFPND SISSEKKAPS GSELISYQPM YDLSDILDTD DGNNDQEASR 120
  121 RQMQTQSSVL NTPRHEL

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


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