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View Structure Prediction Details

Protein: gsto-2
Organism: Caenorhabditis elegans
Length: 537 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gsto-2.

Description E-value Query
Range
Subject
Range
gi|8052534 - gi|8052534|gb|AAF71798.1|AC013430_7 F3F9.11 [Arabidopsis thaliana]
279.0 [0..16] [475..2]

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Predicted Domain #1
Region A:
Residues: [1-238]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTVLAGVNSK IVKNGCWNHS YLQHAILPVA QRALIYASVK NIPSDVINVH LQEKPDWYFS  60
   61 KHYKGQVPTL EHDEGKKHVI ESAVIPEYLD DIYPETRILP TDPYEKVQQK LLLDRISGQV 120
  121 SPAFYGVVQA VKNPDLREEK FADIKKAYDN AEQLLTGDFY SGTSKPGFVD YLLYPNIQRA 180
  181 YWAAHIVPDF PLEAESFPGP NYPRLSKWYK ALESIPEVAA ASQPTENGVG FFKDYLGG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 45.522879
Match: 2cz2A
Description: Crystal structure of glutathione transferase zeta 1-1 (maleylacetoacetate isomerase) from Mus musculus (form-1 crystal)
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [239-537]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SPNYDYGFIP HVITRLTFIS FYVHLSSSKI NFKNLHCRTI AERRSMSVLS GLNTKVVKNG  60
   61 DPAPAPPASG TIRIYNMRYC PWAQRALIFA SLKKIPTEVI NIHLDQKPDW FFTKHYKGQV 120
  121 PALEHDEGKK IVIESAVIPE YLDDIYPEPR IIPTDHYEKV QQKLLLDRIS GQLSSAFYGV 180
  181 VQAAKISDLL KEKLVELAKA YDTAEELLTG DFYSGTSKPG FVDYLIYPNI QRAFWTSHII 240
  241 KDFPLKVESF PGPNYPKLSK WYKRLDSIPE VIATSQPTET AVEFFKSWII GAPNFDYGL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 50.69897
Match: 1eemA
Description: Class omega GST
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
antioxidant activity 3.26520127994042 bayes_pls_golite062009
peroxidase activity 2.96616905270619 bayes_pls_golite062009
oxidoreductase activity, acting on peroxide as acceptor 2.96616905270619 bayes_pls_golite062009
peroxiredoxin activity 2.12777217096121 bayes_pls_golite062009
thioredoxin peroxidase activity 1.96134566495756 bayes_pls_golite062009
glutathione peroxidase activity 1.84498211544043 bayes_pls_golite062009
oxidoreductase activity, acting on sulfur group of donors 1.66635539173786 bayes_pls_golite062009
disulfide oxidoreductase activity 1.14955061683324 bayes_pls_golite062009
catalytic activity 0.672192331361968 bayes_pls_golite062009
maleylacetoacetate isomerase activity 0.426921894831614 bayes_pls_golite062009
binding 0.419658151482326 bayes_pls_golite062009
oxidoreductase activity 0.314980210547407 bayes_pls_golite062009
protein binding 0.034515546627104 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle