YRC Public Data Repository - Protein Structure Prediction

Protein:	TMEM20
Organism:	Homo sapiens
Length:	365 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TMEM20.

Description	E-value	Query Range	Subject Range
gi\|114631860 - gi\|114631860\|ref\|XP_521566.2\| PREDICTED: transmembrane protein 20 [Pan troglodytes]	1.0E-40	[1..365]	[1..365]
gi\|60468186 - gi\|60468186\|gb\|EAL66196.1\| hypothetical protein DDB0204910 [Dictyostelium discoideum] gi\|66812030, gi\|... - gi\|66812030\|ref\|XP_640194.1\| hypothetical protein [Dictyostelium discoideum AX4], gi\|60468186\|gb\|EAL...	4.0E-39	[66..359]	[212..510]
gi\|62642238 - gi\|62642238\|ref\|XP_220029.2\| PREDICTED: similar to transmembrane protein 20 [Rattus norvegicus]	6.0E-39	[6..364]	[11..367]
gi\|23397492, gi\|... - gi\|55661494\|emb\|CAH73399.1\| transmembrane protein 20 [Homo sapiens], gi\|23397492\|ref\|NP_694958.1\| tr...	9.0E-39	[1..365]	[1..364]
gi\|109089992 - gi\|109089992\|ref\|XP_001093499.1\| PREDICTED: similar to transmembrane protein 20 [Macaca mulatta]	3.0E-36	[1..365]	[1..363]
S35G1_MOUSE - Solute carrier family 35 member G1 OS=Mus musculus GN=Slc35g1 PE=2 SV=1	3.0E-36	[13..365]	[18..368]
gi\|73998339 - gi\|73998339\|ref\|XP_543936.2\| PREDICTED: similar to transmembrane protein 20 [Canis familiaris]	8.0E-33	[30..360]	[113..445]
gi\|28203124, gi\|... - gi\|28210686\|ref\|NP_781630.1\| membrane spanning protein [Clostridium tetani E88], gi\|28203124\|gb\|AAO3...	4.0E-31	[70..360]	[6..290]
gi\|69150293, gi\|... - gi\|69938720\|ref\|ZP_00633133.1\| Protein of unknown function DUF6 [Paracoccus denitrificans PD1222], g...	1.0E-30	[25..364]	[231..561]

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Predicted Domain #1

Region A:
Residues: [1-77]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRPQDSTGVA ELQEPGLPLT DDAPPGATEE PAAAEAAGAP DRGRCWLCLS SPCCSRTEPE  60
   61 AKKKAPCPGL GLFYTLL

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [78-209]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SAFLFSVGSL FVKKVQDVHA VEISAFRCVF QMLVVIPCLI YRKTGFIGPK GQRIFLILRG  60
   61 VLGSTAMMLI YYAYQTMSLA DATVITFSSP VFTSIFAWIC LKEKYSPWDA LFTVFTITGV 120
  121 ILIVRPPFLF GS

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	2.21
Match:	2i68A
Description:	No description for 2i68A was found.

Predicted Domain #3

Region A:
Residues: [210-365]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DTSGMEESYS GHLKGTFAAI GSAVFAASTL VILRKMGKSV DYFLSIWYYV VLGLVESVII  60
   61 LSVLGEWSLP YCGLDRLFLI FIGLFGLGGQ IFITKALQIE KAGPVAIMKT MDVVFAFIFQ 120
  121 IIFFNNVPTW WTVGGALCVV ASNVGAAIRK WYQSSK

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits