YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|71041838
Organism:	Homo sapiens
Length:	191 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|71041838.

Description	E-value	Query Range	Subject Range
gi\|50746789 - gi\|50746789\|ref\|XP_420655.1\| PREDICTED: similar to eIF-4E [Gallus gallus]	288.0	[0..1]	[191..76]
gi\|67969074 - gi\|67969074\|dbj\|BAE00892.1\| unnamed protein product [Macaca fascicularis]	281.0	[0..1]	[191..50]
gi\|94370433 - gi\|94370433\|ref\|XP_930840.2\| PREDICTED: similar to eIF-4E [Mus musculus]	280.0	[0..1]	[191..27]
IF4E_BOVIN - (Q9N0T5) Eukaryotic translation initiation factor 4E (eIF4E) (eIF-4E) (mRNA cap-binding protein)	280.0	[0..1]	[191..27]
gi\|60830630 - gi\|60830630\|gb\|AAX36938.1\| eukaryotic translation initiation factor 4E [synthetic construct]	279.0	[0..1]	[191..27]
gi\|74001995 - gi\|74001995\|ref\|XP_544992.2\| PREDICTED: similar to Eukaryotic translation initiation factor 4E (eIF4...	279.0	[0..1]	[191..27]
EIF4E - eukaryotic translation initiation factor 4E gi\|60819169, gi\|... - gi\|61363092\|gb\|AAX42333.1\| eukaryotic translation initiation factor 4E [synthetic construct], gi\|608... gi\|90078144 - gi\|90078144\|dbj\|BAE88752.1\| unnamed protein product [Macaca fascicularis] ENSPTRT00000030331 - null HGNC:3287\|MIM:13... - translation initiation factor 4E gi\|109075052 - gi\|109075052\|ref\|XP_001104976.1\| PREDICTED: similar to Eukaryotic translation initiation factor 4E (...	279.0	[0..1]	[191..27]
IF4E_RABIT - Eukaryotic translation initiation factor 4E OS=Oryctolagus cuniculus GN=EIF4E PE=1 SV=1	279.0	[0..1]	[191..27]
IF4E_MOUSE - Eukaryotic translation initiation factor 4E OS=Mus musculus GN=Eif4e PE=1 SV=1 IF4E_RAT - Eukaryotic translation initiation factor 4E OS=Rattus norvegicus GN=Eif4e PE=1 SV=1	279.0	[0..1]	[191..27]

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Predicted Domain #1

Region A:
Residues: [1-191]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EVANPEHYIK HPLQNRWALW FFKNDKSKTW QANLRLISKF DTVEDFWALY NHIQLSSNLM  60
   61 PGCDYSLFKD GIEPMWEDEK NKRGGRWLIT LNKQQRRSDL DRFWLETLLC LIGESFDDYS 120
  121 DDVCGAVVNV RAKGDKIAIW TTECENREAV THIGRVYKER LGLPPKIVIG YQSHADTATK 180
  181 SGSTTKNRFV V

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	75.522879
Match:	1ipbA
Description:	Translation initiation factor eIF4e
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits