YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: daf-12
Organism: Caenorhabditis elegans
Length: 719 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for daf-12.

Description E-value Query
Range
Subject
Range
daf-12 - status:Confirmed UniProt:Q9XZD4 protein_id:CAC42284.1
339.0 [0..16] [719..50]

Back

Predicted Domain #1
Region A:
Residues: [1-177]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MADNLLSSQN YINWTMLNKF YGKPQMSTPD DPVIHSPPSI GAAPGMNGYH GSGVKLEESS  60
   61 GACGSPDDGL LDSSEESRRR QKTCRVCGDH ATGYNFNVIT CESCKAFFRR NALRPKEFKC 120
  121 PYSEDCEINS VSRRFCQKCR LRKCFTVGMK KEWILNEEQL RRRKNSRLNN TGTCNKR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 26.522879
Match: 2a66A
Description: Human Liver Receptor Homologue DNA-Binding Domain (hLRH-1 DBD) in Complex with dsDNA from the hCYP7A1 Promoter
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [178-379]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SQPGNQQSPQ GPNQQPHLSP HHPGVAIYPP QPQRPLTINP MDNQMMHHMQ ANRPNAMPQL  60
   61 ISPPGAQPYP LTSPVGSSAS DSPPNRSLTM MHNGEKSPDG YDPNIMAHRA PPPSFNNRPK 120
  121 MDSGQVVLST EEYKQLLSRI PGAQVPGLMN EEEPINKRAA YNCNGHPMPA ETTPPYSAPM 180
  181 SDMSLSRHNS TSSGTEKNHM TH

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [380-719]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 STVSAIPGNS AQNHFDIASF GMGIVTATGG GDAAEEMYKR MNMFYENCIQ SALDSPENQE  60
   61 PKPQEAMIPK EEYMTPTHGF QYQSDPYQVP PAERNINYQL NAAELKALDA VREAFYGMDD 120
  121 PMEQGRQMQS FLKANKTPAD IMNIMDVTMR RFVKVAKGVP AFREVSQEGK FSLLKGGMIE 180
  181 MLTVRGVTRY DASTNSFKTP TIKGQNVSVN VDDMFAKLNA NAQAQKAKCL EFFGFFDEEI 240
  241 KKNELAVYLV MLAVLFSVRS DPPMNENDVR IVTERHNHFM SLLNRYLESL FGEQARRIFE 300
  301 RIPKALGLLN EIARNAGMLF MGTVRSGEAE ELPGEFFKIK 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 45.69897
Match: 1z5xE
Description: hemipteran ecdysone receptor ligand-binding domain complexed with ponasterone A
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle