YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|61680194
Organism:	Homo sapiens
Length:	283 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|61680194.

Description	E-value	Query Range	Subject Range
gi\|114599953 - gi\|114599953\|ref\|XP_517728.2\| PREDICTED: cyclin B1 [Pan troglodytes]	275.0	[0..1]	[281..259]
gi\|60655945 - gi\|60655945\|gb\|AAX32536.1\| cyclin B1 [synthetic construct]	269.0	[0..1]	[281..156]
CCNB1, CGB1 - chorionic gonadotropin, beta polypeptide 1, cyclin B1 gi\|123990181 - gi\|123990181\|gb\|ABM83901.1\| cyclin B1 [synthetic construct]	268.0	[0..1]	[281..156]
gi\|109077471 - gi\|109077471\|ref\|XP_001091170.1\| PREDICTED: cyclin B1 isoform 2 [Macaca mulatta]	266.0	[0..1]	[281..155]
gi\|73949659, gi\|... - gi\|73988334\|ref\|XP_851164.1\| PREDICTED: similar to G2/mitotic-specific cyclin B1 isoform 1 [Canis fa...	264.0	[0..1]	[281..148]
gi\|33416373, gi\|... - gi\|45501371\|gb\|AAH67192.1\| Cyclin B1 [Danio rerio], gi\|33416373\|gb\|AAH55553.1\| Cyclin B1 [Danio reri...	262.0	[0..1]	[282..122]
gi\|74139290 - gi\|74139290\|dbj\|BAE40792.1\| unnamed protein product [Mus musculus]	261.0	[0..1]	[281..153]

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Predicted Domain #1

Region A:
Residues: [1-283]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IIAPSRGSPL PVLSWANREE VWKIMLNKEK TYLRDQHFLE QHPLLQPKMR AILLDWLMEV  60
   61 CEVYKLHRET FYLAQDFFDR YMATQENVVK TLLQLIGISS LFIAAKLEEI YPPKLHQFAY 120
  121 VTDGACSGDE ILTMELMIMK ALKWRLSPLT IVSWLNVYMQ VAYLNDLHEV LLPQYPQQIF 180
  181 IQIAELLDLC VLDVDCLEFP YGILAASALY HFSSSELMQK VSGYQWCDIE NCVKWMVPFA 240
  241 MVIRETGSSK LKHFRGVADE DAHNIQTHRD SLDLLDKARA KKA

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	59.045757
Match:	1w98B
Description:	The structural basis of CDK2 activation by cyclin E
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits