YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|61680158, gi\|...
Organism:	Homo sapiens
Length:	195 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|61680158, gi|....

Description	E-value	Query Range	Subject Range
gi\|60653309, gi\|... - gi\|60653309\|gb\|AAX29349.1\| thymidine kinase 1 soluble [synthetic construct], gi\|33303757\|gb\|AAQ02392...	224.0	[0..11]	[195..9]
TK1 - thymidine kinase 1, soluble gi\|60656371, gi\|... - gi\|60656371\|gb\|AAX32749.1\| thymidine kinase 1 [synthetic construct], gi\|60656369\|gb\|AAX32748.1\| thym... HGNC:11830\|MIM:1... - kinase 1, soluble ENSPTRT00000017814 - null	224.0	[0..11]	[195..9]
gi\|94385496, gi\|... - gi\|94385496\|ref\|XP_001004635.1\| PREDICTED: similar to Thymidine kinase, cytosolic isoform 2 [Mus mus...	223.0	[0..16]	[195..15]
gi\|109118477 - gi\|109118477\|ref\|XP_001107944.1\| PREDICTED: thymidine kinase 1, soluble isoform 3 [Macaca mulatta]	223.0	[0..11]	[195..9]
gi\|73964971 - gi\|73964971\|ref\|XP_540462.2\| PREDICTED: similar to Thymidine kinase, cytosolic [Canis familiaris]	221.0	[0..11]	[195..9]
KITH_CRIGR - Thymidine kinase, cytosolic OS=Cricetulus griseus GN=TK1 PE=3 SV=1	221.0	[0..11]	[195..9]
gi\|252871, gi\|298946 - gi\|298946\|gb\|AAB26001.1\| thymidine kinase [Mus sp.], gi\|252871\|gb\|AAB22782.1\| thymidine kinase, TK {... KITH_MOUSE - Thymidine kinase, cytosolic OS=Mus musculus GN=Tk1 PE=1 SV=3	220.0	[0..16]	[195..15]
gi\|152941146, gi... - gi\|76645638\|ref\|XP_580808.2\| PREDICTED: similar to Thymidine kinase, cytosolic isoform 1 [Bos taurus...	220.0	[0..11]	[195..37]

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Predicted Domain #1

Region A:
Residues: [1-195]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRGSHHHHHH LVPRGSKTRG QIQVILGPMF SGKSTELMRR VRRFQIAQYK CLVIKYAKDT  60
   61 RYSSSFCTHD RNTMEALPAC LLRDVAQEAL GVAVIGIDEG QFFPDIVEFC EAMANAGKTV 120
  121 IVAALDGTFQ RKPFGAILNL VPLAESVVKL TAVCMECFRE AAYTKRLGTE KEVEVIGGAD 180
  181 KYHSVCRLCY FKKAS

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	61.522879
Match:	1w4rA
Description:	Structure of a type II thymidine kinase with bound dTTP
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits