YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|56966261, gi\|...
Organism:	Homo sapiens
Length:	208 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|56966261, gi|....

Description	E-value	Query Range	Subject Range
gi\|26335579 - gi\|26335579\|dbj\|BAC31490.1\| unnamed protein product [Mus musculus]	376.0	[0..13]	[208..112]
CD5R1_BOVIN - Cyclin-dependent kinase 5 activator 1 OS=Bos taurus GN=CDK5R1 PE=1 SV=1	376.0	[0..13]	[208..112]
gi\|57091829 - gi\|57091829\|ref\|XP_548274.1\| PREDICTED: similar to cyclin-dependent kinase 5, regulatory subunit 1 i...	375.0	[0..13]	[208..112]
CD5R1_SPECI - Cyclin-dependent kinase 5 activator 1 OS=Spermophilus citellus GN=CDK5R1 PE=2 SV=1	374.0	[0..13]	[208..112]

Back

Predicted Domain #1

Region A:
Residues: [1-208]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QPPPAQPPAP PASQLSGSQT GGSSSVKKAP HPAVTSAGTP KRVIVQASTS ELLRCLGEFL  60
   61 CRRCYRLKHL SPTDPVLWLR SVDRSLLLQG WQDQGFITPA NVVFLYMLCR DVISSEVGSD 120
  121 HELQAVLLTC LYLSYSYMGN EISYPLKPFL VESCKEAFWD RCLSVINLMS SKMLQINADP 180
  181 HYFTQVFSDL KNESGQEDKK RLLLGLDR

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	100.0
Match:	1ungD
Description:	Structural mechanism for the inhibition of CDK5-p25 by roscovitine, aloisine and indirubin.
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits