YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|61680454, gi\|...
Organism:	Mycobacterium tuberculosis
Length:	160 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|61680454, gi|....

Description	E-value	Query Range	Subject Range
gi\|21912927 - gi\|21912927\|emb\|CAC84143.2\| thioredoxin peroxidase [Nicotiana tabacum]	164.0	[0..2]	[159..71]
gi\|11558242, gi\|... - gi\|11558244\|emb\|CAC17804.1\| peroxiredoxin [Phaseolus vulgaris], gi\|11558242\|emb\|CAC17803.1\| peroxire...	161.0	[0..5]	[159..63]
gi\|1076722 - gi\|1076722\|pir\|\|S49173 hypothetical protein - barley (fragment)	161.0	[0..8]	[159..17]
gi\|51892064, gi\|... - gi\|51892064\|ref\|YP_074755.1\| 2-cys peroxiredoxin [Symbiobacterium thermophilum IAM 14863], gi\|518557...	161.0	[0..8]	[160..1]
gi\|111224431, gi... - gi\|111224431\|ref\|YP_715225.1\| peroxiredoxin [Frankia alni ACN14a], gi\|111151963\|emb\|CAJ63685.1\| Pero...	160.0	[0..8]	[158..2]
BAS1_SPIOL - 2-Cys peroxiredoxin BAS1, chloroplastic OS=Spinacia oleracea GN=BAS1 PE=2 SV=1	159.0	[0..8]	[159..72]
BAS1A_ARATH - 2-Cys peroxiredoxin BAS1, chloroplastic OS=Arabidopsis thaliana GN=BAS1 PE=1 SV=2	159.0	[0..8]	[159..72]
gi\|8246810, gi\|2... - gi\|8246810\|emb\|CAB92845.1\| putative thiol-specific antioxidant protein [Streptomyces coelicolor A3(2...	158.0	[0..8]	[158..2]
gi\|3328221 - gi\|3328221\|gb\|AAC78473.1\| thioredoxin peroxidase [Secale cereale]	158.0	[0..8]	[159..64]

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Predicted Domain #1

Region A:
Residues: [1-160]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KVPRGSHMLN VGATAPDFTL RDQNQQLVTL RGYRGAKNVL LVFFPLAFTG IXQGELDQLR  60
   61 DHLPEFENDD SAALAISVGP PPTHKIWATQ SGFTFPLLSD FWPHGAVSQA YGVFNEQAGI 120
  121 ANRGTFVVDR SGIIRFAEMK QPGEVRDQRL WTDALAALTA

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	35.0
Match:	1xvwA
Description:	Crystal Structure of AhpE from Mycobacterium tuberculosis, a 1-Cys peroxiredoxin
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
antioxidant activity	2.80597906644782	bayes_pls_golite062009
peroxidase activity	2.4336549944821	bayes_pls_golite062009
oxidoreductase activity, acting on peroxide as acceptor	2.4336549944821	bayes_pls_golite062009
peroxiredoxin activity	1.37051683183535	bayes_pls_golite062009
thioredoxin peroxidase activity	1.2869732534857	bayes_pls_golite062009
oxidoreductase activity, acting on sulfur group of donors	1.2200856455806	bayes_pls_golite062009
glutathione peroxidase activity	1.08190161740247	bayes_pls_golite062009
catalytic activity	1.04263226837398	bayes_pls_golite062009
disulfide oxidoreductase activity	0.47980406181091	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: