YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|56554706, gi\|...
Organism:	Escherichia coli
Length:	778 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|56554706, gi|....

Description	E-value	Query Range	Subject Range
gi\|170083163, gi... - gi\|170083163\|ref\|YP_001732483.1\| alpha-glucosidase [Escherichia coli str. K-12 substr. DH10B], gi\|16... YICI_ECOLI - Putative family 31 glucosidase yicI - Escherichia coli gi\|238862144, gi... - gi\|238902747\|ref\|YP_002928543.1\| putative alpha-glucosidase [Escherichia coli BW2952], gi\|238862144\|... gi\|89110356, gi\|... - gi\|89110356\|ref\|AP_004136.1\| predicted alpha-glucosidase [Escherichia coli str. K-12 substr. W3110],... gi\|124500136, gi... - gi\|124528997\|ref\|ZP_01700143.1\| glycoside hydrolase, family 31 [Escherichia coli B], gi\|124500136\|gb... EG11685 - putative alpha-glucosidase / Alpha-xylosidase; hexameric EG11685 - putative alpha-glucosidase / Alpha-xylosidase; hexameric gi\|169753042, gi... - gi\|170018114\|ref\|YP_001723068.1\| alpha-xylosidase YicI [Escherichia coli ATCC 8739], gi\|169753042\|gb...	696.0	[0..1]	[772..1]
gi\|75258198, gi\|... - gi\|75258198\|ref\|ZP_00729646.1\| COG1501: Alpha-glucosidases, family 31 of glycosyl hydrolases [Escher...	696.0	[0..1]	[772..1]
gi\|194425169, gi... - gi\|83588496\|ref\|ZP_00927120.1\| COG1501: Alpha-glucosidases, family 31 of glycosyl hydrolases [Escher... gi\|254290335, gi... - gi\|254290335\|ref\|YP_003056083.1\| predicted alpha-glucosidase [Escherichia coli BL21(DE3)], gi\|253979... gi\|242379180, gi... - gi\|251786907\|ref\|YP_003001211.1\| hypothetical protein B21_03466 [Escherichia coli BL21], gi\|24237918... gi\|254163585, gi... - gi\|254163585\|ref\|YP_003046693.1\| predicted alpha-glucosidase [Escherichia coli B str. REL606], gi\|25...	696.0	[0..1]	[772..1]
gi\|90109253, gi\|... - gi\|90109257\|pdb\|2F2H\|F Chain F, Structure Of The Yici Thiosugar Michaelis Complex, gi\|90109256\|pdb\|2...	696.0	[0..1]	[772..1]
gi\|157163137, gi... - gi\|75197559\|ref\|ZP_00707629.1\| COG1501: Alpha-glucosidases, family 31 of glycosyl hydrolases [Escher...	696.0	[0..1]	[772..1]
gi\|117625936, gi... - gi\|117625936\|ref\|YP_859259.1\| alpha-xylosidase YicI [Escherichia coli APEC O1], gi\|115515060\|gb\|ABJ0... gi\|218367505, gi... - gi\|218560736\|ref\|YP_002393649.1\| alpha-xylosidase YicI [Escherichia coli S88], gi\|218367505\|emb\|CAR0... gi\|91213182, gi\|... - gi\|91213182\|ref\|YP_543168.1\| alpha-xylosidase YicI [Escherichia coli UTI89], gi\|91074756\|gb\|ABE09637...	695.0	[0..1]	[772..1]
gi\|157157323, gi... - gi\|75188415\|ref\|ZP_00701682.1\| COG1501: Alpha-glucosidases, family 31 of glycosyl hydrolases [Escher...	695.0	[0..1]	[772..1]
gi\|191170506, gi... - gi\|75242557\|ref\|ZP_00726301.1\| COG1501: Alpha-glucosidases, family 31 of glycosyl hydrolases [Escher... gi\|110345497, gi... - gi\|110643905\|ref\|YP_671635.1\| alpha-xylosidase YicI [Escherichia coli 536], gi\|110345497\|gb\|ABG71734...	694.0	[0..1]	[772..1]
gi\|24054170, gi\|... - gi\|24114926\|ref\|NP_709436.1\| alpha-xylosidase YicI [Shigella flexneri 2a str. 301], gi\|24054170\|gb\|A... gi\|30065068, gi\|... - gi\|30065068\|ref\|NP_839239.1\| alpha-xylosidase YicI [Shigella flexneri 2a str. 2457T], gi\|30043329\|gb...	694.0	[0..1]	[772..1]
gi\|192956309, gi... - gi\|75234815\|ref\|ZP_00719118.1\| COG1501: Alpha-glucosidases, family 31 of glycosyl hydrolases [Escher...	693.0	[0..1]	[772..1]

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Predicted Domain #1

Region A:
Residues: [1-778]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKISDGNWLI QPGLNLIHPL QVFEVEQQDN EMVVYAAPRD VRERTWQLDT PLFTLRFFSP  60
   61 QEGIVGVRIE HFQGALNNGP HYPLNILQDV KVTIENTERY AEFKSGNLSA RVSKGEFWSL 120
  121 DFLRNGERIT GSQVKNNGYV QDTNNQRNYM FERLDLGVGE TVYGLGERFT ALVRNGQTVE 180
  181 TWNRDGGTST EQAYKNIPFY MTNRGYGVLV NHPQCVSFEV GSEKVSKVQF SVESEYLEYF 240
  241 VIDGPTPKAV LDRYTRFTGR PALPPAWSFG LWLTTSFTTN YDEATVNSFI DGMAERNLPL 300
  301 HVFHFDCFWM KAFQWCDFEW DPLTFPDPEG MIRRLKAKGL KICVWINPYI GQKSPVFKEL 360
  361 QEKGYLLKRP DGSLWQWDKW QPGLAIYDFT NPDACKWYAD KLKGLVAMGV DCFKTDFGER 420
  421 IPTDVQWFDG SDPQKMHNHY AYIYNELVWN VLKDTVGEEE AVLFARSASV GAQKFPVHWG 480
  481 GDCYANYESM AESLRGGLSI GLSGFGFWSH DIGGFENTAP AHVYKRWCAF GLLSSHSRLH 540
  541 GSKSYRVPWA YDDESCDVVR FFTQLKCRMM PYLYREAARA NARGTPMMRA MMMEFPDDPA 600
  601 CDYLDRQYML GDNVMVAPVF TEAGDVQFYL PEGRWTHLWH NDELDGSRWH KQQHGFLSLP 660
  661 VYVRDNTLLA LGNNDQRPDY VWHEGTAFHL FNLQDGHEAV CEVPAADGSV IFTLKAARTG 720
  721 NTITVTGAGE AKNWTLCLRN VVKVNGLQDG SQAESEQGLV VKPQGNALTI TLHHHHHH

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	1000.0
Match:	1we5A
Description:	Crystal Structure of Alpha-Xylosidase from Escherichia coli
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	1.32563207632796	bayes_pls_golite062009
hydrolase activity	0.85514037342026	bayes_pls_golite062009
hydrolase activity, acting on glycosyl bonds	0.80912338090552	bayes_pls_golite062009
hydrolase activity, hydrolyzing O-glycosyl compounds	0.41375210927547	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: