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View Structure Prediction Details

Protein: gi|58177362
Organism: Homo sapiens
Length: 294 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|58177362.

Description E-value Query
Range
Subject
Range
gi|56693609 - gi|56693609|gb|AAW22615.1| protection of telomeres protein 1 variant 3 [Homo sapiens]
433.0 [0..1] [294..6]
gi|114615760 - gi|114615760|ref|XP_519345.2| PREDICTED: hypothetical protein isoform 3 [Pan troglodytes]
433.0 [0..1] [294..6]
gi|109068051, gi... - gi|109068051|ref|XP_001087820.1| PREDICTED: protection of telomeres 1 isoform 2 [Macaca mulatta], gi...
433.0 [0..1] [294..6]
POTE1_MACFA - Protection of telomeres protein 1 OS=Macaca fascicularis GN=POT1 PE=2 SV=1
433.0 [0..1] [294..6]

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Predicted Domain #1
Region A:
Residues: [1-294]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ATNYIYTPLN QLKGGTIVNV YGVVKFFKPP YLSKGTDYCS VVTIVDQTNV KLTCLLFSGN  60
   61 YEALPIIYKN GDIVRFHRLK IQVYKKETQG ITSSGFASLT FEGTLGAPII PRTSSKYFNF 120
  121 TTEDHKMVEA LRVWASTHMS PSWTLLKLCD VQPMQYFDLT CQLLGKAEVD GASFLLKVWD 180
  181 GTRTPFPSWR VLIQDLVLEG DLSHIHRLQN LTIDILVYDN HVHVARSLKV GSFLRIYSLH 240
  241 TKLQSMNSEN QTMLSLEFHL HGGTSYGRGI RVLPESNSDV DQLKKDLESA NLTA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 122.0
Match: 1xjvA
Description: Crystal structure of human POT1 bound to telomeric single-stranded DNA (TTAGGGTTAG)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 0.141433535514844 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle