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View Structure Prediction Details

Protein: PTPLA
Organism: Homo sapiens
Length: 288 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PTPLA.

Description E-value Query
Range
Subject
Range
gi|109088316 - gi|109088316|ref|XP_001091308.1| PREDICTED: similar to protein tyrosine phosphatase-like, member A [...
0.0 [1..288] [1..288]
gi|6650693 - gi|6650693|gb|AAF21976.1|AF114494_1 putative tyrosine phosphatase [Homo sapiens]
0.0 [1..288] [1..288]
gi|60031581 - gi|60031581|ref|NP_038963.2| protein tyrosine phosphatase-like (proline instead of catalytic arginin...
2.0E-98 [1..288] [1..285]
HACD1_SHEEP - Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 1 OS=Ovis aries GN=HACD1 PE=2 SV=1
1.0E-96 [1..288] [1..288]
HACD1_CANLF - Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 1 OS=Canis lupus familiaris GN=HACD1 PE=2 SV=1
4.0E-92 [40..288] [1..249]

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Predicted Domain #1
Region A:
Residues: [1-133]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGRLTEAAAA GSGSRAAGWA GSPPTLLPLS PTSPRCAATM ASSDEDGTNG GASEAGEDRE  60
   61 APGERRRLGV LATAWLTFYD IAMTAGWLVL AIAMVRFYME KGTHRGLYKS IQKTLKFFQT 120
  121 FALLEIVHCL IGI

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [134-288]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VPTSVIVTGV QVSSRIFMVW LITHSIKPIQ NEESVVLFLV AWTVTEITRY SFYTFSLLDH  60
   61 LPYFIKWARY NFFIILYPVG VAGELLTIYA ALPHVKKTGM FSIRLPNKYN VSFDYYYFLL 120
  121 ITMASYIPLF PQLYFHMLRQ RRKVLHGEVI VEKDD

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 97.468521
Match: PF04387.5
Description: No description for PF04387.5 was found.

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle