YRC Public Data Repository - Protein Structure Prediction

Protein:	SKIV2L2
Organism:	Homo sapiens
Length:	1042 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SKIV2L2.

Description	E-value	Query Range	Subject Range
gi\|6633995, gi\|2... - gi\|6633995\|dbj\|BAA06124.2\| KIAA0052 protein [Homo sapiens], sp\|P42285\|K052_HUMAN Protein KIAA0052	0.0	[1..1042]	[5..1046]
gi\|114600242 - gi\|114600242\|ref\|XP_001145794.1\| PREDICTED: superkiller viralicidic activity 2-like 2 isoform 2 [Pan...	0.0	[1..1042]	[1..1042]
gi\|149059353, gi... - gi\|77539760\|ref\|NP_001029265.1\| superkiller viralicidic activity 2-like 2 [Rattus norvegicus], gi\|14...	0.0	[1..1042]	[1..1042]
gi\|114325466 - gi\|114325466\|gb\|AAH28604.3\| Superkiller viralicidic activity 2-like 2 (S. cerevisiae) [Homo sapiens] gi\|61363854 - gi\|61363854\|gb\|AAX42455.1\| KIAA0052 protein [synthetic construct]	0.0	[1..1042]	[1..1042]
SK2L2_MOUSE - Superkiller viralicidic activity 2-like 2 OS=Mus musculus GN=Skiv2l2 PE=1 SV=1 gi\|71681012 - gi\|71681012\|gb\|AAH99802.1\| RGD1305984 protein [Rattus norvegicus]	0.0	[1..1042]	[1..1040]
gi\|73949523 - gi\|73949523\|ref\|XP_849676.1\| PREDICTED: similar to Superkiller viralicidic activity 2-like 2 isoform...	0.0	[1..1042]	[1..1042]

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Predicted Domain #1

Region A:
Residues: [1-116]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MADAFGDELF SVFEGDSTTA AGTKKDKEKD KGKWKGPPGS ADKAGKRFDG KLQSESTNNG  60
   61 KNKRDVDFEG TDEPIFGKKP RIEESITEDL SLADLMPRVK VQSVETVEGC THEVAL

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [117-207]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PAEEDYLPLK PRVGKAAKEY PFILDAFQRE AIQCVDNNQS VLVSAHTSAG KTVCAEYAIA  60
   61 LALREKQRVI FTSPIKALSN QKYREMYEEF Q

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	32.522879
Match:	2p6rA
Description:	No description for 2p6rA was found.

Predicted Domain #3

Region A:
Residues: [208-688]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DVGLMTGDVT INPTASCLVM TTEILRSMLY RGSEVMREVA WVIFDEIHYM RDSERGVVWE  60
   61 ETIILLPDNV HYVFLSATIP NARQFAEWIC HLHKQPCHVI YTDYRPTPLQ HYIFPAGGDG 120
  121 LHLVVDENGD FREDNFNTAM QVLRDAGDLA KGDQKGRKGG TKGPSNVFKI VKMIMERNFQ 180
  181 PVIIFSFSKK DCEAYALQMT KLDFNTDEEK KMVEEVFSNA IDCLSDEDKK LPQVEHVLPL 240
  241 LKRGIGIHHG GLLPILKETI EILFSEGLIK ALFATETFAM GINMPARTVL FTNARKFDGK 300
  301 DFRWISSGEY IQMSGRAGRR GMDDRGIVIL MVDEKMSPTI GKQLLKGSAD PLNSAFHLTY 360
  361 NMVLNLLRVE EINPEYMLEK SFYQFQHYRA IPGVVEKVKN SEEQYNKIVI PNEESVVIYY 420
  421 KIRQQLAKLG KEIEEYIHKP KYCLPFLQPG RLVKVKNEGD DFGWGVVVNF SKKSNVKPNS 480
  481 G

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	18.154902
Match:	2v1xA
Description:	No description for 2v1xA was found.

Predicted Domain #4

Region A:
Residues: [689-862]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ELDPLYVVEV LLRCSKESLK NSATEAAKPA KPDEKGEMQV VPVLVHLLSA ISSVRLYIPK  60
   61 DLRPVDNRQS VLKSIQEVQK RFPDGIPLLD PIDDMGIQDQ GLKKVIQKVE AFEHRMYSHP 120
  121 LHNDPNLETV YTLCEKKAQI AIDIKSAKRE LKKARTVLQM DELKCRKRVL RRLG

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	17.0
Match:	1ofcX
Description:	nucleosome recognition module of ISWI ATPase
Matching Structure (courtesy of the PDB):

Predicted Domain #5

Region A:
Residues: [863-1042]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FATSSDVIEM KGRVACEISS ADELLLTEMM FNGLFNDLSA EQATALLSCF VFQENSSEMP  60
   61 KLTEQLAGPL RQMQECAKRI AKVSAEAKLE IDEETYLSSF KPHLMDVVYT WATGATFAHI 120
  121 CKMTDVFEGS IIRCMRRLEE LLRQMCQAAK AIGNTELENK FAEGITKIKR DIVFAASLYL 180
  181

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits