YRC Public Data Repository - Protein Structure Prediction

Protein:	NADD_CAMJR
Organism:	Campylobacter jejuni RM1221
Length:	181 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for NADD_CAMJR.

Description	E-value	Query Range	Subject Range
gi\|58255112, gi\|... - gi\|58337795\|ref\|YP_194380.1\| putative nicotinate-nucleotide adenyltransferase [Lactobacillus acidoph... gi\|227867820, gi... - gi\|227904445\|ref\|ZP_04022250.1\| nicotinate-nucleotide adenylyltransferase [Lactobacillus acidophilus...	165.0	[0..3]	[178..30]
gi\|48825491 - ref\|ZP_00286739.1\| COG1057: Nicotinic acid mononucleotide adenylyltransferase [Enterococcus faecium] gi\|69245738, gi\|... - gi\|69245738\|ref\|ZP_00603604.1\| Cytidyltransferase-related:Probable nicotinate-nucleotide adenylyltra... gi\|293571010\|ref... - nicotinate (nicotinamide) nucleotide adenylyltransferase [Enterococcus faecium E980]	165.0	[0..3]	[177..29]
gi\|21325123, gi\|... - gi\|62391195\|ref\|YP_226597.1\| nicotinic acid mononucleotide adenylyltransferase [Corynebacterium glut...	165.0	[0..2]	[179..18]
gi\|28493436, gi\|... - gi\|28493436\|ref\|NP_787597.1\| nicotinic acid mononucleotide adenylyltransferase [Tropheryma whipplei ...	165.0	[0..2]	[178..12]
gi\|54014851, gi\|... - gi\|54023343\|ref\|YP_117585.1\| nicotinic acid mononucleotide adenylyltransferase [Nocardia farcinica I...	164.0	[0..2]	[179..19]
gi\|6714685, gi\|2... - gi\|6714685\|emb\|CAB66257.1\| putative nicotinate-nucleotide adenylyltransferase [Streptomyces coelicol...	164.0	[0..2]	[178..47]
NADD_THET8 - Probable nicotinate-nucleotide adenylyltransferase OS=Thermus thermophilus (strain HB8 / ATCC 27634 ...	164.0	[0..1]	[178..1]
NADD_GEOKA - Probable nicotinate-nucleotide adenylyltransferase OS=Geobacillus kaustophilus GN=nadD PE=3 SV=1 NADD_GEOKA - Probable nicotinate-nucleotide adenylyltransferase OS=Geobacillus kaustophilus (strain HTA426) GN=na...	164.0	[0..2]	[178..3]
gi\|89084457, gi\|... - gi\|89100811\|ref\|ZP_01173663.1\| nicotinic acid mononucleotide adenyltransferase [Bacillus sp. NRRL B-...	164.0	[0..2]	[179..3]

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Predicted Domain #1

Region A:
Residues: [1-181]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKIALFGGSF DPPHNGHNSV VLEALEKLDI DKLIIMPTYI NPFKQSFSAD EKQRFLWVKK  60
   61 LWGHLPKVEI CDFEIRQKRP VPSIESVKYL YKLYNPSKFY LLIGADHLEK LHLWHDFEKL 120
  121 NSLVEFVIAN RNDIGIPKNF KDLKTNKKIA SSFIRDTLNT NEVCEEIKDE VKKYYEKLQK 180
  181 N

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	39.0
Match:	1kamA
Description:	Nicotinamide mononucleotide (NMN) adenylyltransferase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
nicotinate-nucleotide adenylyltransferase activity	2.83520682135534	bayes_pls_golite062009
nicotinamide-nucleotide adenylyltransferase activity	2.57110502211876	bayes_pls_golite062009
ligase activity, forming carbon-oxygen bonds	2.54008423253828	bayes_pls_golite062009
ligase activity, forming aminoacyl-tRNA and related compounds	2.54008423253828	bayes_pls_golite062009
aminoacyl-tRNA ligase activity	2.52910114154477	bayes_pls_golite062009
catalytic activity	2.37674226834122	bayes_pls_golite062009
ligase activity	1.92894388839884	bayes_pls_golite062009
adenylyltransferase activity	1.08055019963499	bayes_pls_golite062009
pantetheine-phosphate adenylyltransferase activity	0.454904507512502	bayes_pls_golite062009
pantoate-beta-alanine ligase activity	0.282286652169846	bayes_pls_golite062009
nucleotidyltransferase activity	0.2293846471193	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: