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View Structure Prediction Details

Protein: MURB_STRP1
Organism: Streptococcus pyogenes serotype M1
Length: 295 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MURB_STRP1.

Description E-value Query
Range
Subject
Range
MURB_STRPC - UDP-N-acetylenolpyruvoylglucosamine reductase OS=Streptococcus pyogenes serotype M12 (strain MGAS942...
MURB_STRPB - UDP-N-acetylenolpyruvoylglucosamine reductase OS=Streptococcus pyogenes serotype M12 (strain MGAS209...
312.0 [0..1] [295..1]

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Predicted Domain #1
Region A:
Residues: [1-295]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MITELHGIDI RENEPLKHYT YTKVGGPADF LAFPRNHYEL SRIVAYANKE NMPWLVLGNA  60
   61 SNLIVRDGGI RGFVIMFDKL NAVHLNGYTL EAEAGANLIE TTKIAKFHSL TGFEFACGIP 120
  121 GSIGGAVFMN AGAYGGEISH IFLSAKVLTP SGEIKTISAR DMAFGYRHSA IQETGDIVIS 180
  181 AKFALKPGNY DTISQEMNRL NHLRQLKQPL EFPSCGSVFK RPPGHFAGQL IMEANLKGHR 240
  241 IGGVEVSEKH TGFMINVADG TAKDYEDLIA YVIETVENHS GVRLEPEVRI IGENL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 80.221849
Match: 1hskA
Description: Uridine diphospho-N-Acetylenolpyruvylglucosamine reductase (MurB), N-terminal domain; Uridine diphospho-N-Acetylenolpyruvylglucosamine reductase, MurB, C-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
catalytic activity 0.907182340515553 bayes_pls_golite062009
binding 0.088001219122031 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle