YRC Public Data Repository - Protein Structure Prediction

Protein:	NSMCE4A
Organism:	Homo sapiens
Length:	385 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for NSMCE4A.

Description	E-value	Query Range	Subject Range
gi\|114633101 - gi\|114633101\|ref\|XP_001157827.1\| PREDICTED: hypothetical protein [Pan troglodytes]	0.0	[1..385]	[1..385]
gi\|109090779 - gi\|109090779\|ref\|XP_001101717.1\| PREDICTED: hypothetical protein LOC54780 [Macaca mulatta]	0.0	[1..385]	[1..385]
gi\|8923009, gi\|7... - gi\|8923009\|ref\|NP_060085.1\| non-SMC element 4 homolog A [Homo sapiens], gi\|7019815\|dbj\|BAA90881.1\| u...	0.0	[1..385]	[1..385]
gi\|149067593, gi... - gi\|62641388\|ref\|XP_215089.3\| PREDICTED: similar to Protein C10orf86 [Rattus norvegicus], gi\|14906759...	0.0	[1..385]	[1..381]
NSE4A_BOVIN - Non-structural maintenance of chromosomes element 4 homolog A OS=Bos taurus GN=NSMCE4A PE=2 SV=1	0.0	[1..385]	[1..382]
gi\|242246981, gi... - gi\|94382856\|ref\|XP_992770.1\| PREDICTED: similar to Protein C10orf86 [Mus musculus], gi\|82915091\|ref\|...	0.0	[1..385]	[1..381]
gi\|42549259, gi\|... - gi\|46128295\|ref\|XP_388701.1\| hypothetical protein FG08525.1 [Gibberella zeae PH-1], gi\|42549259\|gb\|E...	0.0	[4..385]	[633..1065]

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Predicted Domain #1

Region A:
Residues: [1-226]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSGDSSGRGP EGRGRGRDPH RDRTRSRSRS RSPLSPRSRR GSARERREAP ERPSLEDTEP  60
   61 SDSGDEMMDP ASLEAEADQG LCRQIRHQYR ALINSVQQNR EDILNAGDKL TEVLEEANTL 120
  121 FNEVSRAREA VLDAHFLVLA SDLGKEKAKQ LRSDLSSFDM LRYVETLLTH MGVNPLEAEE 180
  181 LIRDEDSPDF EFIVYDSWKI TGRTAENTFN KTHTFHFLLG SIYGEC

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [227-385]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PVPKPRVDRP RKVPVIQEER AMPAQLRRME ESHQEATEKE VERILGLLQT YFREDPDTPM  60
   61 SFFDFVVDPH SFPRTVENIF HVSFIIRDGF ARIRLDQDRL PVIEPVSINE ENEGFEHNTQ 120
  121 VRNQGIIALS YRDWEEIVKT FEISEPVITP SQRQQKPSA

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

		MCM Score	GO Score	GO Term	SCOP Match	SCOP Description
View	Download	0.826	N/A	N/A	c.25.1	Ferredoxin reductase-like, C-terminal NADP-linked domain
View	Download	0.670	N/A	N/A	c.25.1	Ferredoxin reductase-like, C-terminal NADP-linked domain
View	Download	0.662	N/A	N/A	c.30.1	PreATP-grasp domain
View	Download	0.642	N/A	N/A	c.25.1	Ferredoxin reductase-like, C-terminal NADP-linked domain
View	Download	0.553	N/A	N/A	c.26.3	UDP-glucose/GDP-mannose dehydrogenase C-terminal domain

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits