YRC Public Data Repository - Protein Structure Prediction

Protein:	NSMCE4A
Organism:	Homo sapiens
Length:	385 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for NSMCE4A.

Description	E-value	Query Range	Subject Range
gi\|114633101 - gi\|114633101\|ref\|XP_001157827.1\| PREDICTED: hypothetical protein [Pan troglodytes]	0.0	[1..385]	[1..385]
gi\|109090779 - gi\|109090779\|ref\|XP_001101717.1\| PREDICTED: hypothetical protein LOC54780 [Macaca mulatta]	0.0	[1..385]	[1..385]
gi\|8923009, gi\|7... - gi\|8923009\|ref\|NP_060085.1\| non-SMC element 4 homolog A [Homo sapiens], gi\|7019815\|dbj\|BAA90881.1\| u...	0.0	[1..385]	[1..385]
gi\|149067593, gi... - gi\|62641388\|ref\|XP_215089.3\| PREDICTED: similar to Protein C10orf86 [Rattus norvegicus], gi\|14906759...	0.0	[1..385]	[1..381]
NSE4A_BOVIN - Non-structural maintenance of chromosomes element 4 homolog A OS=Bos taurus GN=NSMCE4A PE=2 SV=1	0.0	[1..385]	[1..382]
gi\|242246981, gi... - gi\|94382856\|ref\|XP_992770.1\| PREDICTED: similar to Protein C10orf86 [Mus musculus], gi\|82915091\|ref\|...	0.0	[1..385]	[1..381]
gi\|42549259, gi\|... - gi\|46128295\|ref\|XP_388701.1\| hypothetical protein FG08525.1 [Gibberella zeae PH-1], gi\|42549259\|gb\|E...	0.0	[4..385]	[633..1065]

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Predicted Domain #1

Region A:
Residues: [1-226]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSGDSSGRGP EGRGRGRDPH RDRTRSRSRS RSPLSPRSRR GSARERREAP ERPSLEDTEP  60
   61 SDSGDEMMDP ASLEAEADQG LCRQIRHQYR ALINSVQQNR EDILNAGDKL TEVLEEANTL 120
  121 FNEVSRAREA VLDAHFLVLA SDLGKEKAKQ LRSDLSSFDM LRYVETLLTH MGVNPLEAEE 180
  181 LIRDEDSPDF EFIVYDSWKI TGRTAENTFN KTHTFHFLLG SIYGEC

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [227-385]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PVPKPRVDRP RKVPVIQEER AMPAQLRRME ESHQEATEKE VERILGLLQT YFREDPDTPM  60
   61 SFFDFVVDPH SFPRTVENIF HVSFIIRDGF ARIRLDQDRL PVIEPVSINE ENEGFEHNTQ 120
  121 VRNQGIIALS YRDWEEIVKT FEISEPVITP SQRQQKPSA

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

		MCM Score	GO Score	GO Term	SCOP Match	SCOP Description
View	Download	0.826	N/A	N/A	c.25.1	Ferredoxin reductase-like, C-terminal NADP-linked domain

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits