YRC Public Data Repository - Protein Structure Prediction

Protein:	CDD_PHOLL
Organism:	Photorhabdus luminescens subsp. laumondii
Length:	294 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CDD_PHOLL.

Description	E-value	Query Range	Subject Range
CDD_YERPY - Cytidine deaminase OS=Yersinia pseudotuberculosis serotype O:3 (strain YPIII) GN=cdd PE=3 SV=1 CDD_YERPG - Cytidine deaminase OS=Yersinia pestis bv. Antiqua (strain Angola) GN=cdd PE=3 SV=1 CDD_YERP3 - Cytidine deaminase OS=Yersinia pseudotuberculosis serotype O:1b (strain IP 31758) GN=cdd PE=3 SV=1 gi\|165924607, gi... - gi\|165924607\|ref\|ZP_02220439.1\| cytidine deaminase [Yersinia pestis biovar Orientalis str. F1991016]... CDD_YERPE - Cytidine deaminase OS=Yersinia pestis GN=cdd PE=3 SV=1 gi\|149366433, gi... - gi\|149366433\|ref\|ZP_01888467.1\| cytidine deaminase [Yersinia pestis CA88-4125], gi\|149290807\|gb\|EDM4... gi\|166211692, gi... - gi\|166211692\|ref\|ZP_02237727.1\| cytidine deaminase [Yersinia pestis biovar Antiqua str. B42003004], ... CDD_YERPP - Cytidine deaminase OS=Yersinia pestis (strain Pestoides F) GN=cdd PE=3 SV=1 gi\|166009352, gi... - gi\|166009352\|ref\|ZP_02230250.1\| cytidine deaminase [Yersinia pestis biovar Antiqua str. E1979001], g... gi\|45441227, gi\|... - gi\|45441227\|ref\|NP_992766.1\| cytidine deaminase [Yersinia pestis biovar Microtus str. 91001], gi\|454... gi\|167421843, gi... - gi\|167421843\|ref\|ZP_02313596.1\| cytidine deaminase [Yersinia pestis biovar Orientalis str. MG05-1020... gi\|229689212, gi... - gi\|229843604\|ref\|ZP_04463747.1\| cytidine/deoxycytidine deaminase [Yersinia pestis biovar Orientalis ... gi\|21959536, gi\|... - gi\|22126535\|ref\|NP_669958.1\| cytidine deaminase [Yersinia pestis KIM], gi\|21959536\|gb\|AAM86209.1\|AE0... gi\|167050312, gi... - gi\|167400363\|ref\|ZP_02305876.1\| cytidine deaminase [Yersinia pestis biovar Antiqua str. UG05-0454], ... gi\|229894292, gi... - gi\|229894292\|ref\|ZP_04509475.1\| cytidine/deoxycytidine deaminase [Yersinia pestis Pestoides A], gi\|2... gi\|167469199 - gi\|167469199\|ref\|ZP_02333903.1\| cytidine deaminase [Yersinia pestis FV-1] gi\|115347264, gi... - gi\|218928653\|ref\|YP_002346528.1\| cytidine deaminase [Yersinia pestis CO92], gi\|16121785\|ref\|NP_40509... gi\|167424271, gi... - gi\|167424271\|ref\|ZP_02316024.1\| cytidine deaminase [Yersinia pestis biovar Mediaevalis str. K1973002... CDD_YERPA - Cytidine deaminase OS=Yersinia pestis bv. Antiqua (strain Antiqua) GN=cdd PE=3 SV=1 CDD_YERPN - Cytidine deaminase OS=Yersinia pestis bv. Antiqua (strain Nepal516) GN=cdd PE=3 SV=1 gi\|165939620, gi... - gi\|89105603\|ref\|ZP_01178119.1\| COG0295: Cytidine deaminase [Yersinia pestis biovar Orientalis str. I...	375.0	[0..1]	[294..1]

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Predicted Domain #1

Region A:
Residues: [1-294]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQARFHPIWV QLPSKLQDAL LPYAGNDDFP AMLTAEQAKS IKKACGFDDN TLAVALLPLA  60
   61 AASSLTPISH FNVGAIARGE SGNLYFGANM EFAGVPLQQT IHAEQCAITH AWLLGEKRLA 120
  121 SVTVNYSPCG HCRQFMNELN SGTQLEIHLP KQASSTLDHY LPDSFGPNDL GITTLLMDPV 180
  181 NHGYKLETTD KLVLTALDAA NQSYAPYSNS YSGTALLGKD GIIYPGRYAE NAAFNPSLPP 240
  241 LQAALILMNI SGGDCLAIER AVLVEGKHSD LSQRSATQSI LAALGCSKFD YYTF

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	102.0
Match:	1af2A
Description:	Two-domain cytidine deaminase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
cytidine deaminase activity	4.42667374679603	bayes_pls_golite062009
deaminase activity	2.76997916054448	bayes_pls_golite062009
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines	2.27736397496642	bayes_pls_golite062009
catalytic activity	1.70756445127105	bayes_pls_golite062009
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	1.51294035758003	bayes_pls_golite062009
IMP cyclohydrolase activity	1.11605611485835	bayes_pls_golite062009
phosphoribosylaminoimidazolecarboxamide formyltransferase activity	0.827438033765078	bayes_pls_golite062009
hydrolase activity	0.339145951258927	bayes_pls_golite062009
cyclohydrolase activity	0.308525511259279	bayes_pls_golite062009
binding	0.255962198799579	bayes_pls_golite062009
hydroxymethyl-, formyl- and related transferase activity	0.1546696349714	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: