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View Structure Prediction Details

Protein: Alr-PA
Organism: Drosophila melanogaster
Length: 261 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Alr-PA.

Description E-value Query
Range
Subject
Range
gi|220947962 - gi|220947962|gb|ACL86524.1| CG12534-PA [synthetic construct]
gi|24643392, gi|... - gi|24643392|ref|NP_608353.1| CG12534-PA [Drosophila melanogaster], gi|22832612|gb|AAF49017.2| CG1253...
262.0 [0..69] [261..1]
gi|125981799, gi... - gi|54643215|gb|EAL31959.1| GA11683-PA [Drosophila pseudoobscura], gi|125981799|ref|XP_001354903.1| G...
261.0 [0..1] [261..1]
gi|39961850, gi|... - gi|39961850|ref|XP_364723.1| hypothetical protein MG09568.4 [Magnaporthe grisea 70-15], gb|EAA53818....
242.0 [0..69] [259..1]
gi|28921166, gi|... - gi|32421457|ref|XP_331172.1| hypothetical protein [Neurospora crassa], gi|28921166|gb|EAA30480.1| au...
gi|85093549 - gi|85093549|ref|XP_959716.1| augmenter of liver regeneration [Neurospora crassa OR74A]
223.0 [0..72] [261..7]
gi|151943312 - gi|151943312|gb|EDN61625.1| sulfhydryl oxidase [Saccharomyces cerevisiae YJM789]
ERV1 - Flavin-linked sulfhydryl oxidase of the mitochondrial intermembrane space (IMS), oxidizes Mia40p as ...
gi|190406945 - gi|190406945|gb|EDV10212.1| sulfhydryl oxidase [Saccharomyces cerevisiae RM11-1a]
ERV1_YEAST - Mitochondrial FAD-linked sulfhydryl oxidase ERV1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S...
220.0 [0..90] [255..12]
gi|7576256 - gi|7576256|emb|CAB87993.1| augmenter of liver regeneration [Homo sapiens]
219.0 [0..84] [261..51]
gi|109127227 - gi|109127227|ref|XP_001082639.1| PREDICTED: similar to erv1-like growth factor isoform 2 [Macaca mul...
212.0 [0..82] [261..52]

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Predicted Domain #1
Region A:
Residues: [1-91]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIFTIAERSF KILELPTTPT LLLRRQSHNY GYDYISPTHI ELSREATRLV IRRLQRTVLR  60
   61 LIRDPDFIMS AEANPEMDKE HHESPFAANR K

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [92-139]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AGASGAGKQD SNCRTCNDFK SWSKQQRLIS NVQSAKVKHM AAAEKLTV

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [140-261]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NAAEDPLPRD DCPLDKVRLG ISTWGLLHTM AAFYSDNPTD TEKRDMKTFF EVLSRLYPCE  60
   61 FCAKDFRTDL DVNPINVNSQ KELALWLCKF HNRVNDKLGK PLFDCTKVNE RWRDGWLDGS 120
  121 CD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 46.39794
Match: 1oqcA
Description: Augmenter of liver regeneration
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
oxidoreductase activity, acting on sulfur group of donors, oxygen as acceptor 8.87150227689427 bayes_pls_golite062009
thiol oxidase activity 8.35075284009652 bayes_pls_golite062009
flavin-linked sulfhydryl oxidase activity 3.45360739809667 bayes_pls_golite062009
oxidoreductase activity, acting on sulfur group of donors 2.80346464149611 bayes_pls_golite062009
binding 1.31466847278576 bayes_pls_golite062009
protein binding 0.425029114798138 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle