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View Structure Prediction Details

Protein: tpk-1
Organism: Caenorhabditis elegans
Length: 243 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for tpk-1.

Description E-value Query
Range
Subject
Range
gi|83755026, gi|... - gi|83755027|pdb|2F17|B Chain B, Mouse Thiamin Pyrophosphokinase In A Ternary Complex With Pyrithiami...
268.0 [0..1] [234..21]

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Predicted Domain #1
Region A:
Residues: [1-243]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSKKLKPFEI LEDSCASVCI WLNGEPTAIS NRAENLWNKA KYRVATDGAV NEILKRKSFV  60
   61 EWPHIICGDF DSINKQIDTK NAKVVHLPDQ DYTDLSKSVQ WCLEQKTLTS WEFENIVVLG 120
  121 GLNGRFDHTM STLSSLIRFV DSQTPVIVLD SRNLVLAVPT GDSNLDVNLE MTTKMCGIIP 180
  181 IVQKETIVSS IGLKYEMENL ALEFGKLIST SNEVTTSQVF LKSSSSLIFS IELENWVYKL 240
  241 DSL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 72.0
Match: 1ig3A
Description: Thiamin pyrophosphokinase, substrate-binding domain; Thiamin pyrophosphokinase, catalytic domain
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle