YRC Public Data Repository - Protein Structure Prediction

Protein:	METTL11A
Organism:	Homo sapiens
Length:	223 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for METTL11A.

Description	E-value	Query Range	Subject Range
NTM1A_MOUSE - N-terminal Xaa-Pro-Lys N-methyltransferase 1 OS=Mus musculus GN=Ntmt1 PE=1 SV=3	4.0E-43	[1..223]	[1..223]
NTM1A_RAT - N-terminal Xaa-Pro-Lys N-methyltransferase 1 OS=Rattus norvegicus GN=Ntmt1 PE=2 SV=3	8.0E-43	[1..223]	[1..223]
gi\|114627144, gi... - gi\|55632451\|ref\|XP_520309.1\| PREDICTED: similar to Chromosome 9 open reading frame 32 isoform 5 [Pan...	2.0E-41	[1..223]	[1..223]
NTM1A_BOVIN - N-terminal Xaa-Pro-Lys N-methyltransferase 1 OS=Bos taurus GN=NTMT1 PE=2 SV=3	5.0E-41	[1..223]	[1..223]
gi\|83755009, gi\|... - gi\|83755010\|pdb\|2EX4\|B Chain B, Crystal Structure Of Human Methyltransferase Ad-003 In Complex With ...	6.0E-41	[2..223]	[20..241]
gi\|73967997 - gi\|73967997\|ref\|XP_548421.2\| PREDICTED: similar to CG1675-PA [Canis familiaris]	3.0E-40	[1..223]	[23..245]
NT1AB_XENLA - N-terminal Xaa-Pro-Lys N-methyltransferase 1-B OS=Xenopus laevis GN=ntmt1-b PE=2 SV=1	9.0E-39	[1..223]	[1..223]

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Predicted Domain #1

Region A:
Residues: [1-223]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTSEVIEDEK QFYSKAKTYW KQIPPTVDGM LGGYGHISSI DINSSRKFLQ RFLREGPNKT  60
   61 GTSCALDCGA GIGRITKRLL LPLFREVDMV DITEDFLVQA KTYLGEEGKR VRNYFCCGLQ 120
  121 DFTPEPDSYD VIWIQWVIGH LTDQHLAEFL RRCKGSLRPN GIIVIKDNMA QEGVILDDVD 180
  181 SSVCRDLDVV RRIICSAGLS LLAEERQENL PDEIYHVYSF ALR

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	42.39794
Match:	2ex4A
Description:	Crystal Structure of Human methyltransferase AD-003 in complex with S-adenosyl-L-homocysteine
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits