| Protein: | FLT1 |
| Organism: | Homo sapiens |
| Length: | 1338 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FLT1.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [1..1338] | [1..1338] |
|
|
0.0 | [1..1338] | [144..1481] |
|
|
0.0 | [1..1338] | [1..1338] |
|
|
0.0 | [1..1337] | [1..1335] |
|
|
0.0 | [1..1338] | [1..1337] |
|
|
0.0 | [1..1337] | [1..1332] |
|
|
0.0 | [11..1338] | [9..1327] |
|
Region A: Residues: [1-132] |
1 11 21 31 41 51
| | | | | |
1 MVSYWDTGVL LCALLSCLLL TGSSSGSKLK DPELSLKGTQ HIMQAGQTLH LQCRGEAAHK 60
61 WSLPEMVSKE SERLSITKSA CGRNGKQFCS TLTLNTAQAN HTGFYSCKYL AVPTSKKKET 120
121 ESAIYIFISD TG
|
| Detection Method: |  |
| Confidence: | 7.045757 |
| Match: | 1dl7H |
| Description: | Immunoglobulin heavy chain variable domain, VH |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| nucleic acid binding | 2.13338563453164 | bayes_pls_golite062009 |
|
Region A: Residues: [133-227] |
1 11 21 31 41 51
| | | | | |
1 RPFVEMYSEI PEIIHMTEGR ELVIPCRVTS PNITVTLKKF PLDTLIPDGK RIIWDSRKGF 60
61 IISNATYKEI GLLTCEATVN GHLYKTNYLT HRQTN
|
| Detection Method: | |
| Confidence: | 7.69897 |
| Match: | 1qsvA |
| Description: | Second domain of the Flt-1 receptor |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [228-645] |
1 11 21 31 41 51
| | | | | |
1 TIIDVQISTP RPVKLLRGHT LVLNCTATTP LNTRVQMTWS YPDEKNKRAS VRRRIDQSNS 60
61 HANIFYSVLT IDKMQNKDKG LYTCRVRSGP SFKSVNTSVH IYDKAFITVK HRKQQVLETV 120
121 AGKRSYRLSM KVKAFPSPEV VWLKDGLPAT EKSARYLTRG YSLIIKDVTE EDAGNYTILL 180
181 SIKQSNVFKN LTATLIVNVK PQIYEKAVSS FPDPALYPLG SRQILTCTAY GIPQPTIKWF 240
241 WHPCNHNHSE ARCDFCSNNE ESFILDADSN MGNRIESITQ RMAIIEGKNK MASTLVVADS 300
301 RISGIYICIA SNKVGTVGRN ISFYITDVPN GFHVNLEKMP TEGEDLKLSC TVNKFLYRDV 360
361 TWILLRTVNN RTMHYSISKQ KMAITKEHSI TLNLTIMNVS LQDSGTYACR ARNVYTGE
|
| Detection Method: | |
| Confidence: | 3.30103 |
| Match: | 2gy5A |
| Description: | No description for 2gy5A was found. |
|
Region A: Residues: [646-800] |
1 11 21 31 41 51
| | | | | |
1 EILQKKEITI RDQEAPYLLR NLSDHTVAIS SSTTLDCHAN GVPEPQITWF KNNHKIQQEP 60
61 GIILGPGSST LFIERVTEED EGVYHCKATN QKGSVESSAY LTVQGTSDKS NLELITLTCT 120
121 CVAATLFWLL LTLFIRKMKR SSSEIKTDYL SIIMD
|
| Detection Method: | |
| Confidence: | 5.25 |
| Match: | 2iepA |
| Description: | No description for 2iepA was found. |
|
Region A: Residues: [801-834] |
1 11 21 31 41 51
| | | | | |
1 PDEVPLDEQC ERLPYDASKW EFARERLKLG KSLG
|
| Detection Method: | |
| Confidence: | 56.09691 |
| Match: | 1y6aA |
| Description: | Crystal structure of VEGFR2 in complex with a 2-anilino-5-aryl-oxazole inhibitor |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [835-1226] |
1 11 21 31 41 51
| | | | | |
1 RGAFGKVVQA SAFGIKKSPT CRTVAVKMLK EGATASEYKA LMTELKILTH IGHHLNVVNL 60
61 LGACTKQGGP LMVIVEYCKY GNLSNYLKSK RDLFFLNKDA ALHMEPKKEK MEPGLEQGKK 120
121 PRLDSVTSSE SFASSGFQED KSLSDVEEEE DSDGFYKEPI TMEDLISYSF QVARGMEFLS 180
181 SRKCIHRDLA ARNILLSENN VVKICDFGLA RDIYKNPDYV RKGDTRLPLK WMAPESIFDK 240
241 IYSTKSDVWS YGVLLWEIFS LGGSPYPGVQ MDEDFCSRLR EGMRMRAPEY STPEIYQIML 300
301 DCWHRDPKER PRFAELVEKL GDLLQANVQQ DGKDYIPINA ILTGNSGFTY STPAFSEDFF 360
361 KESISAPKFN SGSSDDVRYV NAFKFMSLER IK
|
| Detection Method: | |
| Confidence: | 49.09691 |
| Match: | 1pmeA |
| Description: | STRUCTURE OF PENTA MUTANT HUMAN ERK2 MAP KINASE COMPLEXED WITH A SPECIFIC INHIBITOR OF HUMAN P38 MAP KINASE |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [1227-1338] |
1 11 21 31 41 51
| | | | | |
1 TFEELLPNAT SMFDDYQGDS STLLASPMLK RFTWTDSKPK ASLKIDLRVT SKSKESGLSD 60
61 VSRPSFCHSS CGHVSEGKRR FTYDHAELER KIACCSPPPD YNSVVLYSTP PI
|
| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
| MCM Score |
SCOP Match |
SCOP Description | ||
| View | Download | 0.375 | c.23.1 | CheY-like |
| View | Download | 0.303 | a.100.1 | 6-phosphogluconate dehydrogenase C-terminal domain-like |
| View | Download | 0.263 | a.73.1 | Retrovirus capsid protein, N-terminal core domain |
| View | Download | 0.340 | d.45.1 | ClpS-like |
| View | Download | 0.259 | a.23.1 | HSC20 (HSCB), C-terminal oligomerisation domain |
