YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|12698670, gi\|...
Organism:	Homo sapiens
Length:	447 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|12698670, gi|....

Description	E-value	Query Range	Subject Range
gi\|76628636 - gi\|76628636\|ref\|XP_594575.2\| PREDICTED: similar to alpha 2b adrenergic receptor [Bos taurus]	6.0E-75	[1..447]	[202..648]
gi\|66268793 - gi\|66268793\|gb\|AAY43127.1\| adrenergic, alpha-2B-, receptor isoform [Homo sapiens]	4.0E-70	[1..447]	[1..450]
gi\|109104751 - gi\|109104751\|ref\|XP_001082230.1\| PREDICTED: alpha-2B-adrenergic receptor [Macaca mulatta]	8.0E-68	[1..447]	[1..445]
gi\|73980799 - gi\|73980799\|ref\|XP_854447.1\| PREDICTED: similar to Alpha-2B adrenergic receptor (Alpha-2B adrenocept...	7.0E-67	[1..447]	[1..444]
ADA2B_RAT - Alpha-2B adrenergic receptor OS=Rattus norvegicus GN=Adra2b PE=2 SV=2	2.0E-66	[1..447]	[6..453]
gi\|80971508, gi\|... - gi\|80971508\|ref\|NP_001032225.1\| alpha-2B-adrenergic receptor [Sus scrofa], gi\|76886507\|gb\|ABA60362.1...	2.0E-66	[1..447]	[1..446]
gi\|14193666, gi\|... - gi\|191548\|gb\|AAA37131.1\| alpha-2 adrenergic receptor [Mus musculus], gi\|148696240\|gb\|EDL28187.1\| adr...	3.0E-66	[3..447]	[3..448]

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Predicted Domain #1

Region A:
Residues: [1-311]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDHQDPYSVQ ATAAIAAAIT FLILFTIFGN ALVILAVLTS RSLRAPQNLF LVSLAAADIL  60
   61 VATLIIPFSL ANELLGYWYF RRTWCEVYLA LDVLFCTSSI VHLCAISLDR YWAVSRALEY 120
  121 NSKRTPRRIK CIILTVWLIA AVISLPPLIY KGDQGPQPRG RPQCKLNQEA WYILASSIGS 180
  181 FFAPCLIMIL VYLRIYLIAK RSNRRGPRAK GGPGQGESKQ PRPDHGGALA SAKLPALASV 240
  241 ASAREVNGHS KSTGEKEEGE TPEDTGTRAL PPSWAALPNS GQGQKEGVCG ASPEDEAEEE 300
  301 EEEEEECEPQ A

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	31.522879
Match:	1f88A
Description:	Rhodopsin
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [312-447]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VPVSPASACS PPLQQPQGSR VLATLRGQVL LGRGVGAIGG QWWRRRAQLT REKRFTFVLA  60
   61 VVIGVFVLCW FPFFFSYSLG AICPKHCKVP HGLFQFFFWI GYCNSSLNPV IYTIFNQDFR 120
  121 RAFRRILCRP WTQTAW

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	5.38
Match:	1f88A
Description:	Rhodopsin
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits