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View Structure Prediction Details

Protein: gi|539728
Organism: Sus scrofa domesticus
Length: 131 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|539728.

Description E-value Query
Range
Subject
Range
gi|7689351 - gi|7689351|gb|AAF67742.1| relaxin-like protein [Cervus dama]
150.0 [0..1] [131..1]
INSL3_PANTR - Insulin-like 3 OS=Pan troglodytes GN=INSL3 PE=3 SV=1
148.0 [0..1] [131..1]
INSL3 - insulin-like 3 (Leydig cell)
148.0 [0..1] [131..1]
gi|67078442, gi|... - gi|94429011|gb|ABF18930.1| insulin-like protein 3 [Ovis aries], gi|67078442|ref|NP_001019909.1| insu...
145.0 [0..1] [131..1]
gi|38607270 - gi|38607270|gb|AAR25542.1| relaxin-like peptide hormone INSL3 [Capreolus capreolus]
145.0 [0..1] [131..1]
gi|7331160 - gi|7331160|gb|AAF60301.1|AF233686_1 RLF [Capra hircus]
143.0 [0..1] [131..1]

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Predicted Domain #1
Region A:
Residues: [1-131]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDPHPLTWAL VLLGPALALS RAPAPAQEAP EKLCGHHFVR ALVRLCGGPR WSPEDGRAVA  60
   61 GGDRELLQWL EGQHLFHGLM ASGDPMLVLA PQPPPQASGH HHHRRAAATN PARHCCLSGC 120
  121 TRQDLLTLCP H

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 15.39794
Match: 1efeA
Description: Insulin
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
receptor binding 4.17791426687122 bayes_pls_golite062009
growth factor activity 2.72622283405236 bayes_pls_golite062009
insulin receptor binding 2.63140197547721 bayes_pls_golite062009
binding 2.10822082471133 bayes_pls_golite062009
insulin-like growth factor receptor binding 2.00701807224409 bayes_pls_golite062009
protein binding 1.91565532265649 bayes_pls_golite062009
hormone activity 1.5588633384762 bayes_pls_golite062009
protein complex binding 0.713029123952647 bayes_pls_golite062009
growth factor binding 0.2746507992289 bayes_pls_golite062009
insulin-like growth factor binding 0.00273016120581948 bayes_pls_golite062009
protease binding 0.00116373646030077 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle