YRC Public Data Repository - Protein Structure Prediction

Protein:	FTSH3_ARATH
Organism:	Arabidopsis thaliana
Length:	809 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FTSH3_ARATH.

Description	E-value	Query Range	Subject Range
gi\|17380916 - gi\|17380916\|gb\|AAL36270.1\| putative AAA-type ATPase [Arabidopsis thaliana]	683.0	[0..1]	[809..1]
gi\|15021761 - gi\|15021761\|gb\|AAK77908.1\|AF397903_1 AAA-metalloprotease FtsH [Pisum sativum]	559.0	[0..4]	[809..1]
gi\|92873588 - gi\|92873588\|gb\|ABE82014.1\| AAA ATPase; Bacterial luciferase-like; Peptidase M41, FtsH extracellular ...	552.0	[0..4]	[809..1]
FTSH8_ORYSJ - ATP-dependent zinc metalloprotease FTSH 8, mitochondrial OS=Oryza sativa subsp. japonica GN=FTSH8 PE...	533.0	[0..69]	[809..79]
AFG31_MOUSE - AFG3-like protein 1 OS=Mus musculus GN=Afg3l1 PE=1 SV=2	522.0	[0..4]	[807..1]
gi\|205357195, gi... - gi\|205357195\|ref\|ZP_02345811.2\| ATP-dependent metallopeptidase HflB [Salmonella enterica subsp. ente... gi\|197248059, gi... - gi\|197248059\|ref\|YP_002148220.1\| ATP-dependent metallopeptidase HflB [Salmonella enterica subsp. ent... gi\|195873641, gi... - gi\|195873641\|ref\|ZP_02697399.2\| ATP-dependent metallopeptidase HflB [Salmonella enterica subsp. ente... gi\|194471603, gi... - gi\|194471603\|ref\|ZP_03077587.1\| ATP-dependent metallopeptidase HflB [Salmonella enterica subsp. ente... gi\|194447870, gi... - gi\|194447870\|ref\|YP_002047324.1\| ATP-dependent metalloprotease [Salmonella enterica subsp. enterica ... gi\|194442507, gi... - gi\|194442507\|ref\|YP_002042552.1\| ATP-dependent metallopeptidase HflB [Salmonella enterica subsp. ent... gi\|205348591, gi... - gi\|205360607\|ref\|ZP_02684667.2\| ATP-dependent metallopeptidase HflB [Salmonella enterica subsp. ente... gi\|205343557, gi... - gi\|205359745\|ref\|ZP_02831638.2\| ATP-dependent metallopeptidase HflB [Salmonella enterica subsp. ente... gi\|205359196, gi... - gi\|205359196\|ref\|ZP_02668061.2\| ATP-dependent metallopeptidase HflB [Salmonella enterica subsp. ente... gi\|62181804, gi\|... - gi\|62181804\|ref\|YP_218221.1\| ATP-dependent metalloprotease [Salmonella enterica subsp. enterica sero... gi\|205333758, gi... - gi\|205358490\|ref\|ZP_02656962.2\| ATP-dependent metallopeptidase HflB [Salmonella enterica subsp. ente...	517.0	[0..133]	[798..6]

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Predicted Domain #1

Region A:
Residues: [1-124]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTMIFFSKLN RSISRSKGFL YGGGVRSAAR LLTSPGLEAA SVNEVEGGLG FIRRHFASLA  60
   61 SRKGLVNNDL IGVFANPRLR RFFSDEAPKK KNYENYFPKD KQEPKSDQKS EHKEGSEKNE 120
  121 NENV

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

		MCM Score	SCOP Match	SCOP Description
View	Download	0.411	a.121.1	Tetracyclin repressor-like, C-terminal domain
View	Download	0.304	a.47.2	t-snare proteins
View	Download	0.276	a.26.1	4-helical cytokines
View	Download	0.276	a.26.1	4-helical cytokines
View	Download	0.259	a.121.1	Tetracyclin repressor-like, C-terminal domain
View	Download	0.238	a.25.1	Ferritin-like
View	Download	0.238	a.25.1	Ferritin-like
View	Download	0.233	a.4.9	Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3
View	Download	0.218	a.2.7	tRNA-binding arm

Predicted Domain #2

Region A:
Residues: [125-305]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GDMFMNRFQN LLIPLLALAV FFSTFSFGSG EQQQISFQEF KNKLLEPGLV DHIDVSNKSV  60
   61 AKVYVRSTPK DQQTTDVVHG NGNGIPAKRT GGQYKYYFNI GSVDSFEEKL EEAQEALGVD 120
  121 RHEYVPVTYV SEMVWYQEFM RFAPTLLLLG TLIYGARRMQ GGLGVGGTGG KNGRGIFNIG 180
  181 K

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	64.0
Match:	1e32A
Description:	Membrane fusion atpase p97 N-terminal domain , P97-Nn; Membrane fusion atpase p97, D1 domain; Membrane fusion atpase p97 domain 2, P97-Nc
Matching Structure (courtesy of the PDB):

Predicted Domain #3

Region A:
Residues: [306-809]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ATITRADKHS KNKIYFKDVA GCDEAKQEIM EFVHFLKNPK KYEDLGAKIP KGALLVGPPG  60
   61 TGKTLLAKAT AGESGVPFLS ISGSDFMEMF VGVGPSRVRH LFQEARQAAP SIIFIDEIDA 120
  121 IGRARGRGGL GGNDERESTL NQLLVEMDGF GTTAGVVVLA GTNRPDILDK ALLRPGRFDR 180
  181 QITIDKPDIK GRDQIFKIYL KKIKLDHEPS YYSQRLAALT PGFAGADIAN VCNEAALIAA 240
  241 RHEGATVTMA HFESAIDRVI GGLEKKNRVI SKLERRTVAY HESGHAVVGW FLEHAEPLLK 300
  301 VTIVPRGTAA LGFAQYVPNE NLLMTKEQLF DMTCMTLGGR AAEQVLIGKI STGAQNDLEK 360
  361 VTKMTYAQVA VYGFSDKVGL LSFPPRDDGY DFSKPYSNKT GAIIDEEVRD WVAKAYERTV 420
  421 ELVEEHKVKV AEIAELLLEK EVLHQDDLLK ILGERPFKSA EVTNYDRFKS GFEETEKDSA 480
  481 ATPTVEPVVD DGAPPPFEPQ VVPT

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	115.0
Match:	2ce7A
Description:	EDTA treated
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits