YRC Public Data Repository - Protein Structure Prediction

Protein:	MASZ_ECOLI
Organism:	Escherichia coli
Length:	723 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MASZ_ECOLI.

Description	E-value	Query Range	Subject Range
MASZ_PSEA7 - Malate synthase G OS=Pseudomonas aeruginosa (strain PA7) GN=glcB PE=3 SV=1	1001.0	[0..1]	[723..1]
MASZ_PSEA8 - Malate synthase G OS=Pseudomonas aeruginosa (strain LESB58) GN=glcB PE=3 SV=1 gi\|107099468 - gi\|107099468\|ref\|ZP_01363386.1\| hypothetical protein PaerPA_01000480 [Pseudomonas aeruginosa PACS2] MASZ_PSEAB - Malate synthase G OS=Pseudomonas aeruginosa (strain UCBPP-PA14) GN=glcB PE=3 SV=1	999.0	[0..1]	[723..1]
MASZ_PSEAE - Malate synthase G OS=Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228) GN... MASZ_PSEAE - Malate synthase G OS=Pseudomonas aeruginosa GN=glcB PE=3 SV=1	998.0	[0..1]	[723..1]
MASZ_PSEPF - Malate synthase G OS=Pseudomonas fluorescens (strain Pf0-1) GN=glcB PE=3 SV=1	995.0	[0..1]	[723..1]
gi\|83644497, gi\|... - gi\|83644497\|ref\|YP_432932.1\| malate synthase G [Hahella chejuensis KCTC 2396], gi\|83632540\|gb\|ABC285...	995.0	[0..1]	[722..34]
gi\|77866917, gi\|... - gi\|77954162\|ref\|ZP_00818561.1\| Malate synthase G [Marinobacter aquaeolei VT8], gi\|77866917\|gb\|EAO982...	988.0	[0..1]	[723..29]
gi\|67157443, gi\|... - gi\|67157443\|ref\|ZP_00418692.1\| Malate synthase G [Azotobacter vinelandii AvOP], ref\|ZP_00089192.1\| C... gi\|226942747, gi... - gi\|67157443\|ref\|ZP_00418692.1\| Malate synthase G [Azotobacter vinelandii AvOP], gi\|67085351\|gb\|EAM04...	987.0	[0..1]	[723..1]
gi\|89093527, gi\|... - gi\|89093527\|ref\|ZP_01166475.1\| malate synthase [Oceanospirillum sp. MED92], gi\|89082217\|gb\|EAR61441....	986.0	[0..1]	[722..1]
MASZ_PSEFL - Malate synthase G OS=Pseudomonas fluorescens GN=glcB PE=3 SV=1	984.0	[0..1]	[723..1]
gi\|71556989, gi\|... - gi\|71736436\|ref\|YP_276835.1\| malate synthase G [Pseudomonas syringae pv. phaseolicola 1448A], gi\|715...	984.0	[0..1]	[722..1]

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Predicted Domain #1

Region A:
Residues: [1-723]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSQTITQSRL RIDANFKRFV DEEVLPGTGL DAAAFWRNFD EIVHDLAPEN RQLLAERDRI  60
   61 QAALDEWHRS NPGPVKDKAA YKSFLRELGY LVPQPERVTV ETTGIDSEIT SQAGPQLVVP 120
  121 AMNARYALNA ANARWGSLYD ALYGSDIIPQ EGAMVSGYDP QRGEQVIAWV RRFLDESLPL 180
  181 ENGSYQDVVA FKVVDKQLRI QLKNGKETTL RTPAQFVGYR GDAAAPTCIL LKNNGLHIEL 240
  241 QIDANGRIGK DDPAHINDVI VEAAISTILD CEDSVAAVDA EDKILLYRNL LGLMQGTLQE 300
  301 KMEKNGRQIV RKLNDDRHYT AADGSEISLH GRSLLFIRNV GHLMTIPVIW DSEGNEIPEG 360
  361 ILDGVMTGAI ALYDLKVQKN SRTGSVYIVK PKMHGPQEVA FANKLFTRIE TMLGMAPNTL 420
  421 KMGIMDEERR TSLNLRSCIA QARNRVAFIN TGFLDRTGDE MHSVMEAGPM LRKNQMKSTP 480
  481 WIKAYERNNV LSGLFCGLRG KAQIGKGMWA MPDLMADMYS QKGDQLRAGA NTAWVPSPTA 540
  541 ATLHALHYHQ TNVQSVQANI AQTEFNAEFE PLLDDLLTIP VAENANWSAQ EIQQELDNNV 600
  601 QGILGYVVRW VEQGIGCSKV PDIHNVALME DRATLRISSQ HIANWLRHGI LTKEQVQASL 660
  661 ENMAKVVDQQ NAGDPAYRPM AGNFANSCAF KAASDLIFLG VKQPNGYTEP LLHAWRLREK 720
  721 ESH

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	1000.0
Match:	1d8cA
Description:	Malate synthase G
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer	3.42741832724053	bayes_pls_golite062009
malate synthase activity	3.30693406844099	bayes_pls_golite062009
transferase activity, transferring acyl groups	1.77690715624512	bayes_pls_golite062009
catalytic activity	1.60678631669946	bayes_pls_golite062009
transferase activity	0.46418608399558	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: