| Protein: | PARP1 |
| Organism: | Homo sapiens |
| Length: | 1014 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PARP1.
| Description | E-value | Query Range |
Subject Range |
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0.0 | [1..1014] | [1..1014] |
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0.0 | [1..1014] | [1..1014] |
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0.0 | [1..1014] | [1..1013] |
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0.0 | [1..1014] | [1..1013] |
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Region A: Residues: [1-94] |
1 11 21 31 41 51
| | | | | |
1 MAESSDKLYR VEYAKSGRAS CKKCSESIPK DSLRMAIMVQ SPMFDGKVPH WYHFSCFWKV 60
61 GHSIRHPDVE VDGFSELRWD DQQKVKKTAE AGGV
|
| Detection Method: |  |
| Confidence: | 41.0 |
| Match: | 2dmjA |
| Description: | No description for 2dmjA was found. |
|
Region A: Residues: [95-224] |
1 11 21 31 41 51
| | | | | |
1 TGKGQDGIGS KAEKTLGDFA AEYAKSNRST CKGCMEKIEK GQVRLSKKMV DPEKPQLGMI 60
61 DRWYHPGCFV KNREELGFRP EYSASQLKGF SLLATEDKEA LKKQLPGVKS EGKRKGDEVD 120
121 GVDEVAKKKS
|
| Detection Method: | |
| Confidence: | 33.69897 |
| Match: | 2cs2A |
| Description: | Solution structure of the second Zn-finger domain of poly(ADP-ribose) polymerase-1 |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [225-376] |
1 11 21 31 41 51
| | | | | |
1 KKEKDKDSKL EKALKAQNDL IWNIKDELKK VCSTNDLKEL LIFNKQQVPS GESAILDRVA 60
61 DGMVFGALLP CEECSGQLVF KSDAYYCTGD VTAWTKCMVK TQTPNRKEWV TPKEFREISY 120
121 LKKLKVKKQD RIFPPETSAS VAATPPPSTA SA
|
| Detection Method: | |
| Confidence: | 34.823909 |
| Match: | PF08063.3 |
| Description: | No description for PF08063.3 was found. |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [377-507] |
1 11 21 31 41 51
| | | | | |
1 PAAVNSSASA DKPLSNMKIL TLGKLSRNKD EVKAMIEKLG GKLTGTANKA SLCISTKKEV 60
61 EKMNKKMEEV KEANIRVVSE DFLQDVSAST KSLQELFLAH ILSPWGAEVK AEPVEVVAPR 120
121 GKSGAALSKK S
|
| Detection Method: | |
| Confidence: | 13.09691 |
| Match: | 2cokA |
| Description: | Solution structure of BRCT domain of poly(ADP-ribose) polymerase-1 |
Matching Structure (courtesy of the PDB): |
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|
Region A: Residues: [508-645] |
1 11 21 31 41 51
| | | | | |
1 KGQVKEEGIN KSEKRMKLTL KGGAAVDPDS GLEHSAHVLE KGGKVFSATL GLVDIVKGTN 60
61 SYYKLQLLED DKENRYWIFR SWGRVGTVIG SNKLEQMPSK EDAIEHFMKL YEEKTGNAWH 120
121 SKNFTKYPKK FYPLEIDY
|
| Detection Method: | |
| Confidence: | 37.522879 |
| Match: | 2cr9A |
| Description: | Solution structure of WGR domain of poly(ADP-ribose) polymerase-1 |
Matching Structure (courtesy of the PDB): |
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|
Region A: Residues: [646-1014] |
1 11 21 31 41 51
| | | | | |
1 GQDEEAVKKL TVNPGTKSKL PKPVQDLIKM IFDVESMKKA MVEYEIDLQK MPLGKLSKRQ 60
61 IQAAYSILSE VQQAVSQGSS DSQILDLSNR FYTLIPHDFG MKKPPLLNNA DSVQAKVEML 120
121 DNLLDIEVAY SLLRGGSDDS SKDPIDVNYE KLKTDIKVVD RDSEEAEIIR KYVKNTHATT 180
181 HNAYDLEVID IFKIEREGEC QRYKPFKQLH NRRLLWHGSR TTNFAGILSQ GLRIAPPEAP 240
241 VTGYMFGKGI YFADMVSKSA NYCHTSQGDP IGLILLGEVA LGNMYELKHA SHISKLPKGK 300
301 HSVKGLGKTT PDPSANISLD GVDVPLGTGI SSGVNDTSLL YNEYIVYDIA QVNLKYLLKL 360
361 KFNFKTSLW
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| Detection Method: | |
| Confidence: | 150.0 |
| Match: | 1a26A |
| Description: | THE CATALYTIC FRAGMENT OF POLY(ADP-RIBOSE) POLYMERASE COMPLEXED WITH CARBA-NAD |
Matching Structure (courtesy of the PDB): |
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