YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|66522
Organism:	Shigella flexneri
Length:	213 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|66522.

Description	E-value	Query Range	Subject Range
gi\|67677540, gi\|... - gi\|92112984\|ref\|YP_572912.1\| dihydrolipoamide acetyltransferase [Chromohalobacter salexigens DSM 304...	243.0	[0..3]	[213..464]
gi\|119383306, gi... - gi\|69935180\|ref\|ZP_00630160.1\| Dihydrolipoamide succinyltransferase [Paracoccus denitrificans PD1222...	241.0	[0..4]	[213..282]
gi\|114707322, gi... - gi\|114707322\|ref\|ZP_01440219.1\| dihydrolipoamide acetyltransferase [Fulvimarina pelagi HTCC2506], gi...	240.0	[0..4]	[213..317]
gi\|23467322, gi\|... - gi\|23467322\|ref\|ZP_00122905.1\| COG0508: Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoam...	240.0	[0..4]	[213..179]
gi\|32030043, gi\|... - gi\|32030043\|ref\|ZP_00132963.1\| COG0508: Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoam...	240.0	[0..4]	[213..179]
gi\|46202384 - gi\|46202384\|ref\|ZP_00053285.2\| COG0508: Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoam...	240.0	[0..3]	[212..191]
ODO2_HAEIN - Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex OS... ODO2_HAEIN - Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex OS...	239.0	[0..4]	[213..181]
gi\|144982919 - gi\|144982919\|gb\|EDJ90432.1\| carboxy-terminal protease [Haemophilus influenzae R3021] gi\|145639183, gi... - gi\|145639183\|ref\|ZP_01794790.1\| carboxy-terminal protease [Haemophilus influenzae PittII], gi\|145271... gi\|145631489 - gi\|145631489\|ref\|ZP_01787258.1\| carboxy-terminal protease [Haemophilus influenzae 22.4-21] gi\|46133588 - gi\|46133588\|ref\|ZP_00157429.2\| COG0508: Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoam...	239.0	[0..4]	[213..181]
gi\|53732513 - gi\|53732513\|ref\|ZP_00154561.2\| COG0508: Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoam... gi\|48868188, gi\|... - gi\|68250263\|ref\|YP_249375.1\| dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydr...	239.0	[0..4]	[213..181]
gi\|115422744, gi... - gi\|187478158\|ref\|YP_786182.1\| dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase...	238.0	[0..2]	[213..306]

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Predicted Domain #1

Region A:
Residues: [1-213]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNYTKFDVKN WVRREHFEFY RHRLPCGFSL TSKIDITTLK KSLDDSAYKF YPVMIYLIAQ  60
   61 AVNQFDELRM AIKDDELIVW DSVDPQFTVF HQETETFSAL SCPYSSDIDQ FMVNYLSVME 120
  121 RYKSDTKLFP QGVTPENHLN ISALPWVNFD SFNLNVANFT DYFAPIITMA KYQQEGDRLL 180
  181 LPLSVQVHHA VCDGFHVARF INRLQELCNS KLK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	48.154902
Match:	1qcaA
Description:	QUADRUPLE MUTANT Q92C, N146F, Y168F, I172V TYPE III CAT COMPLEXED WITH FUSIDIC ACID. CRYSTALS GROWN AT PH 6.3. X-RAY DATA COLLECTED AT ROOM TEMPERATURE
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
O-acyltransferase activity	1.33427079482946	bayes_pls_golite062009
catalytic activity	1.11963814819322	bayes_pls_golite062009
acetyltransferase activity	1.11363533925208	bayes_pls_golite062009
O-acetyltransferase activity	0.98894401869839	bayes_pls_golite062009
transferase activity	0.779944977611303	bayes_pls_golite062009
transferase activity, transferring acyl groups	0.121738651204904	bayes_pls_golite062009
acyltransferase activity	0.082345605682432	bayes_pls_golite062009
transferase activity, transferring acyl groups other than amino-acyl groups	0.0713143246907167	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: