YRC Public Data Repository - Protein Structure Prediction

Protein:	SYK1_ECOL6
Organism:	Escherichia coli O6
Length:	505 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SYK1_ECOL6.

Description	E-value	Query Range	Subject Range
gi\|77974514, gi\|... - gi\|77974514\|ref\|ZP_00830054.1\| COG1190: Lysyl-tRNA synthetase (class II) [Yersinia frederiksenii ATC...	552.0	[0..1]	[505..1]
gi\|238783658, gi... - gi\|77958933\|ref\|ZP_00822959.1\| COG1190: Lysyl-tRNA synthetase (class II) [Yersinia bercovieri ATCC 4...	548.0	[0..1]	[505..1]
gi\|77963232, gi\|... - gi\|77963232\|ref\|ZP_00827044.1\| COG1190: Lysyl-tRNA synthetase (class II) [Yersinia mollaretii ATCC 4...	548.0	[0..1]	[505..1]
gi\|193063477, gi... - gi\|75258488\|ref\|ZP_00729910.1\| COG1190: Lysyl-tRNA synthetase (class II) [Escherichia coli E22], gi\|...	546.0	[0..1]	[505..1]
gi\|194423804, gi... - gi\|83587253\|ref\|ZP_00925882.1\| COG1190: Lysyl-tRNA synthetase (class II) [Escherichia coli 101-1], g... gi\|254290812, gi... - gi\|254290812\|ref\|YP_003056560.1\| lysine tRNA synthetase, inducible [Escherichia coli BL21(DE3)], gi\|... gi\|251787383, gi... - gi\|251787383\|ref\|YP_003001687.1\| hypothetical protein B21_03962 [Escherichia coli BL21], gi\|24237965... gi\|253975963, gi... - gi\|254164062\|ref\|YP_003047170.1\| lysine tRNA synthetase, inducible [Escherichia coli B str. REL606],...	546.0	[0..1]	[505..1]
gi\|30064202, gi\|... - gi\|30064202\|ref\|NP_838373.1\| lysyl-tRNA synthetase [Shigella flexneri 2a str. 2457T], gi\|30042459\|gb... gi\|73856926, gi\|... - gi\|74313449\|ref\|YP_311868.1\| lysyl-tRNA synthetase [Shigella sonnei Ss046], gi\|73856926\|gb\|AAZ89633.... gi\|192956152, gi... - gi\|75234617\|ref\|ZP_00718948.1\| COG1190: Lysyl-tRNA synthetase (class II) [Escherichia coli E110019],... gi\|218353217, gi... - gi\|218696485\|ref\|YP_002404152.1\| lysyl-tRNA synthetase [Escherichia coli 55989], gi\|218353217\|emb\|CA... gi\|190903919, gi... - gi\|75230862\|ref\|ZP_00717320.1\| COG1190: Lysyl-tRNA synthetase (class II) [Escherichia coli B7A], gi\|... gi\|218555438, gi... - gi\|218555438\|ref\|YP_002388351.1\| lysyl-tRNA synthetase [Escherichia coli IAI1], gi\|218362206\|emb\|CAQ... SYK1_SHIFL - Lysine--tRNA ligase OS=Shigella flexneri GN=lysS PE=3 SV=3 gi\|24114145, gi\|... - gi\|24114145\|ref\|NP_708655.1\| lysyl-tRNA synthetase [Shigella flexneri 2a str. 301], gi\|24053284\|gb\|A... gi\|194426362, gi... - gi\|75212497\|ref\|ZP_00712521.1\| COG1190: Lysyl-tRNA synthetase (class II) [Escherichia coli B171], gi... gi\|75187605, gi\|... - gi\|75187605\|ref\|ZP_00700872.1\| COG1190: Lysyl-tRNA synthetase (class II) [Escherichia coli E24377A],... SYK_SHIB3 - Lysine--tRNA ligase OS=Shigella boydii serotype 18 (strain CDC 3083-94 / BS512) GN=lysS PE=3 SV=1 SYK_SHIF8 - Lysine--tRNA ligase OS=Shigella flexneri serotype 5b (strain 8401) GN=lysS PE=3 SV=1	546.0	[0..1]	[505..1]
gi\|75188845, gi\|... - gi\|75188845\|ref\|ZP_00702112.1\| COG1190: Lysyl-tRNA synthetase (class II) [Escherichia coli E24377A],... gi\|170021873, gi... - gi\|170021873\|ref\|YP_001726827.1\| lysyl-tRNA synthetase [Escherichia coli ATCC 8739], gi\|169756801\|gb... gi\|124527768, gi... - gi\|124527768\|ref\|ZP_01699203.1\| lysyl-tRNA synthetase [Escherichia coli B], gi\|124501211\|gb\|EAY48677...	546.0	[0..1]	[505..1]
SYK2_ECOLI - Lysyl-tRNA synthetase, heat inducible (EC 6.1.1.6) (Lysine--tRNA ligase) (LysRS) - Escherichia coli SYK2_ECO57 - Lysine--tRNA ligase, heat inducible OS=Escherichia coli O157:H7 GN=lysU PE=3 SV=2 EG10553 - lysine tRNA synthetase, inducible / Lysine--tRNA ligase, heat inducible; Ap4A and Ap3A synthase gi\|15804722, gi\|... - gi\|15804722\|ref\|NP_290763.1\| lysyl-tRNA synthetase [Escherichia coli O157:H7 EDL933], gi\|12519106\|gb... gi\|15834365, gi\|... - gi\|15834365\|ref\|NP_313138.1\| lysyl-tRNA synthetase [Escherichia coli O157:H7 str. Sakai], gi\|1336458... gi\|238861695, gi... - gi\|238903238\|ref\|YP_002929034.1\| lysine tRNA synthetase, inducible [Escherichia coli BW2952], gi\|238... gi\|254796152, gi... - gi\|254796152\|ref\|YP_003080989.1\| lysine tRNA synthetase, inducible [Escherichia coli O157:H7 str. TW... gi\|170083579, gi... - gi\|170083579\|ref\|YP_001732899.1\| lysine tRNA synthetase, inducible [Escherichia coli str. K-12 subst... gi\|189379164, gi... - gi\|189379164\|gb\|EDU97580.1\| lysyl-tRNA synthetase LysU [Escherichia coli O157:H7 str. EC508], gi\|168... gi\|208726904, gi... - gi\|208807103\|ref\|ZP_03249440.1\| lysyl-tRNA synthetase LysU [Escherichia coli O157:H7 str. EC4206], g... EG10553 - lysine tRNA synthetase, inducible / Lysine--tRNA ligase, heat inducible; Ap4A and Ap3A synthase gi\|195935919 - gi\|195935919\|ref\|ZP_03081301.1\| lysyl-tRNA synthetase [Escherichia coli O157:H7 str. EC4024] gi\|208819932, gi... - gi\|208819932\|ref\|ZP_03260252.1\| lysyl-tRNA synthetase LysU [Escherichia coli O157:H7 str. EC4042], g... gi\|208735239, gi... - gi\|208813962\|ref\|ZP_03255291.1\| lysyl-tRNA synthetase LysU [Escherichia coli O157:H7 str. EC4045], g... gi\|209921620, gi... - gi\|209921620\|ref\|YP_002295704.1\| lysyl-tRNA synthetase [Escherichia coli SE11], gi\|209914879\|dbj\|BAG... gi\|209162047, gi... - gi\|209400647\|ref\|YP_002273676.1\| lysyl-tRNA synthetase LysU [Escherichia coli O157:H7 str. EC4115], ... gi\|188017408, gi... - gi\|188017408\|gb\|EDU55530.1\| lysyl-tRNA synthetase LysU [Escherichia coli O157:H7 str. EC4113], gi\|16... gi\|168760993, gi... - gi\|189368520\|gb\|EDU86936.1\| lysyl-tRNA synthetase LysU [Escherichia coli O157:H7 str. EC4501], gi\|16... gi\|168755314, gi... - gi\|189357458\|gb\|EDU75877.1\| lysyl-tRNA synthetase LysU [Escherichia coli O157:H7 str. EC4401], gi\|16... gi\|168774502, gi... - gi\|187769884\|gb\|EDU33728.1\| lysyl-tRNA synthetase LysU [Escherichia coli O157:H7 str. EC4196], gi\|16... gi\|168766403, gi... - gi\|189364021\|gb\|EDU82440.1\| lysyl-tRNA synthetase LysU [Escherichia coli O157:H7 str. EC4486], gi\|16... gi\|189375037, gi... - gi\|189375037\|gb\|EDU93453.1\| lysyl-tRNA synthetase LysU [Escherichia coli O157:H7 str. EC869], gi\|168... gi\|189001831, gi... - gi\|189001831\|gb\|EDU70817.1\| lysyl-tRNA synthetase LysU [Escherichia coli O157:H7 str. EC4076], gi\|16... gi\|89110851, gi\|... - gi\|89110851\|ref\|AP_004631.1\| lysine tRNA synthetase, inducible [Escherichia coli str. K-12 substr. W... gi\|218363451, gi... - gi\|218556682\|ref\|YP_002389596.1\| lysyl-tRNA synthetase [Escherichia coli IAI1], gi\|218363451\|emb\|CAR... gi\|188488978, gi... - gi\|75514889\|ref\|ZP_00737118.1\| COG1190: Lysyl-tRNA synthetase (class II) [Escherichia coli 53638], g... gi\|217326188, gi... - gi\|217326188\|ref\|ZP_03442272.1\| lysyl-tRNA synthetase LysU [Escherichia coli O157:H7 str. TW14588], ... gi\|192931307, gi... - gi\|75259047\|ref\|ZP_00730415.1\| COG1190: Lysyl-tRNA synthetase (class II) [Escherichia coli E22], gi\|... gi\|75212057, gi\|... - gi\|75212057\|ref\|ZP_00712112.1\| COG1190: Lysyl-tRNA synthetase (class II) [Escherichia coli B171], gi... gi\|218697832, gi... - gi\|218697832\|ref\|YP_002405499.1\| lysyl-tRNA synthetase [Escherichia coli 55989], gi\|218354564\|emb\|CA... gi\|157069275, gi... - gi\|75197980\|ref\|ZP_00708050.1\| COG1190: Lysyl-tRNA synthetase (class II) [Escherichia coli HS], gi\|1...	546.0	[0..1]	[505..1]
gi\|74314615, gi\|... - gi\|74314615\|ref\|YP_313034.1\| lysyl-tRNA synthetase [Shigella sonnei Ss046], gi\|73858092\|gb\|AAZ90799....	546.0	[0..1]	[505..1]
SYK_SHIDS - Lysine--tRNA ligase OS=Shigella dysenteriae serotype 1 (strain Sd197) GN=lysS PE=3 SV=1	545.0	[0..1]	[505..1]

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Predicted Domain #1

Region A:
Residues: [1-505]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSEQHAQGAD AVVDLNNELK TRREKLANLR EQGIAFPNDF RRDHTSDQLH AEFDGKENEE  60
   61 LEALNIEVAV AGRMMTRRIM GKASFVTLQD VGGRIQLYVA RDDLPEGVYN EQFKKWDLGD 120
  121 ILGAKGKLFK TKTGELSIHC TELRLLTKAL RPLPDKFHGL QDQEARYRQR YLDLISNDES 180
  181 RNTFKVRSQI LSGIRQFMVN RGFMEVETPM MQVIPGGAAA RPFITHHNAL DLDMYLRIAP 240
  241 ELYLKRLVVG GFERVFEINR NFRNEGISVR HNPEFTMMEL YMAYADYKDL IELTESLFRT 300
  301 LAQDILGKTE VTYGDVTLDF GKPFEKLTMR EAIKKYRPET DMADLDNFDS AKAIAESIGI 360
  361 HVEKSWGLGR IVTEIFEEVA EAHLIQPTFI TEYPAEVSPL ARRNDVNPEI TDRFEFFIGG 420
  421 REIGNGFSEL NDAEDQAQRF LDQVAAKDAG DDEAMFYDED YVTALEHGLP PTAGLGIGID 480
  481 RMVMLFTNSH TIRDVILFPA MRPVK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	155.0
Match:	1e1oA
Description:	Lysyl-tRNA synthetase (LysRS)
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits