YRC Public Data Repository - Protein Structure Prediction

Protein:	FRE_ECOLI
Organism:	Escherichia coli
Length:	233 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FRE_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|535285, gi\|628588 - pir\|\|S47292 phenol 2-monooxygenase (EC 1.14.13.7) chain mopP - Acinetobacter calcoaceticus, gi\|53528...	232.0	[0..1]	[230..102]
gi\|2605613 - gi\|2605613\|dbj\|BAA23335.1\| DMS oxygenase component [Acinetobacter sp.]	230.0	[0..1]	[230..102]
gi\|74058076, gi\|... - gi\|74318581\|ref\|YP_316321.1\| CDP-6-deoxy-delta-3,4-glucoseen reductase [Thiobacillus denitrificans A...	228.0	[0..1]	[232..100]
gi\|67084888, gi\|... - gi\|67158154\|ref\|ZP_00419204.1\| Ferredoxin:Oxidoreductase FAD/NAD(P)-binding:Oxidoreductase FAD-bindi... gi\|67158154, gi\|... - gi\|67158154\|ref\|ZP_00419204.1\| Ferredoxin:Oxidoreductase FAD/NAD(P)-binding:Oxidoreductase FAD-bindi...	227.0	[0..1]	[230..100]
gi\|254251643, gi... - gi\|84362620\|ref\|ZP_00987237.1\| COG0543: 2-polyprenylphenol hydroxylase and related flavodoxin oxidor...	225.0	[0..1]	[231..100]
gi\|53729374, gi\|... - gi\|71909404\|ref\|YP_286991.1\| ferredoxin:oxidoreductase FAD/NAD(P)-binding:oxidoreductase FAD-binding...	225.0	[0..1]	[230..102]
gi\|90331996, gi\|... - gi\|90416271\|ref\|ZP_01224203.1\| Ferredoxin:Oxidoreductase FAD/NAD(P)-binding:OxidoreductaseFAD-bindin... gi\|90416271\|ref\|... - Ferredoxin:Oxidoreductase FAD/NAD(P)-binding:OxidoreductaseFAD-binding region [marine gamma proteoba...	225.0	[0..1]	[230..102]
gi\|91784951, gi\|... - gi\|91784951\|ref\|YP_560157.1\| CDP-6-deoxy-delta-3,4-glucoseen reductase [Burkholderia xenovorans LB40...	223.0	[0..1]	[231..100]
gi\|6505661 - gi\|6505661\|dbj\|BAA87873.1\| phenol hydroxylase subunit [Comamonas testosteroni]	223.0	[0..1]	[230..102]

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Predicted Domain #1

Region A:
Residues: [1-233]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTTLSCKVTS VEAITDTVYR VRIVPDAAFS FRAGQYLMVV MDERDKRPFS MASTPDEKGF  60
   61 IELHIGASEI NLYAKAVMDR ILKDHQIVVD IPHGEAWLRD DEERPMILIA GGTGFSYARS 120
  121 ILLTALARNP NRDITIYWGG REEQHLYDLC ELEALSLKHP GLQVVPVVEQ PEAGWRGRTG 180
  181 TVLTAVLQDH GTLAEHDIYI AGRFEMAKIA RDLFCSERNA REDRLFGDAF AFI

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	53.39794
Match:	1qfjA
Description:	NAD(P)H:flavin oxidoreductase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	1.82418089257266	bayes_pls_golite062009
oxidoreductase activity	1.06930052685144	bayes_pls_golite062009
transferase activity	0.20565726169867	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: