YRC Public Data Repository - Protein Structure Prediction

Protein:	ACPS_ECOLI
Organism:	Escherichia coli
Length:	126 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ACPS_ECOLI.

Description	E-value	Query Range	Subject Range
ACPS_VIBPA - Holo-[acyl-carrier-protein] synthase OS=Vibrio parahaemolyticus GN=acpS PE=3 SV=1 gi\|153839831, gi... - gi\|153839831\|ref\|ZP_01992498.1\| holo-(acyl-carrier-protein) synthase [Vibrio parahaemolyticus AQ3810... ACPS_VIBPA - Holo-[acyl-carrier-protein] synthase OS=Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633)...	157.0	[0..1]	[126..1]
ACPS_VIBF1 - Holo-[acyl-carrier-protein] synthase OS=Vibrio fischeri (strain ATCC 700601 / ES114) GN=acpS PE=3 SV...	154.0	[0..1]	[126..1]
gi\|91227848, gi\|... - gi\|91227848\|ref\|ZP_01262021.1\| 4'-phosphopantetheinyl transferase [Vibrio alginolyticus 12G01], gi\|9...	154.0	[0..1]	[126..1]
gi\|84376762, gi\|... - gi\|84390108\|ref\|ZP_00991370.1\| 4'-phosphopantetheinyl transferase [Vibrio splendidus 12B01], gi\|8437...	154.0	[0..1]	[126..1]
ACPS_GEODF - Holo-[acyl-carrier-protein] synthase OS=Geobacter daltonii (strain DSM 22248 / JCM 15807 / FRC-32) G...	153.0	[0..2]	[125..1]
gi\|116183577, gi... - gi\|75854066\|ref\|ZP_00761786.1\| COG0736: Phosphopantetheinyl transferase (holo-ACP synthase) [Vibrio ...	153.0	[0..1]	[126..1]
ACPS_VIBVU - Holo-[acyl-carrier-protein] synthase OS=Vibrio vulnificus GN=acpS PE=3 SV=1 ACPS_VIBVU - Holo-[acyl-carrier-protein] synthase OS=Vibrio vulnificus (strain CMCP6) GN=acpS PE=3 SV=1	153.0	[0..1]	[126..1]
gi\|86146355, gi\|... - gi\|86146355\|ref\|ZP_01064679.1\| 4'-phosphopantetheinyl transferase [Vibrio sp. MED222], gi\|85835834\|g... ACPS_VIBTL - Holo-[acyl-carrier-protein] synthase OS=Vibrio tasmaniensis (strain LGP32) GN=acpS PE=3 SV=1	152.0	[0..1]	[126..1]
gi\|121628741, gi... - gi\|75815088\|ref\|ZP_00745615.1\| COG0736: Phosphopantetheinyl transferase (holo-ACP synthase) [Vibrio ... ACPS_VIBC3 - Holo-[acyl-carrier-protein] synthase OS=Vibrio cholerae serotype O1 (strain ATCC 39541 / Classical O...	152.0	[0..2]	[125..1]
ACPS_VIBVY - Holo-[acyl-carrier-protein] synthase OS=Vibrio vulnificus (strain YJ016) GN=acpS PE=3 SV=1	152.0	[0..1]	[126..1]

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Predicted Domain #1

Region A:
Residues: [1-126]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAILGLGTDI VEIARIEAVI ARSGDRLARR VLSDNEWAIW KTHHQPVRFL AKRFAVKEAA  60
   61 AKAFGTGIRN GLAFNQFEVF NDELGKPRLR LWGEALKLAE KLGVANMHVT LADERHYACA 120
  121 TVIIES

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	29.522879
Match:	1f7tA
Description:	Holo-(acyl carrier protein) synthase ACPS
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
holo-[acyl-carrier-protein] synthase activity	3.16041523883346	bayes_pls_golite062009
phosphotransferase activity, for other substituted phosphate groups	3.07692326713136	bayes_pls_golite062009
catalytic activity	1.85383781679828	bayes_pls_golite062009
transferase activity	0.733560176609492	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	0.571740867528267	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: