YRC Public Data Repository - Protein Structure Prediction

Protein:	STAR
Organism:	Homo sapiens
Length:	285 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for STAR.

Description	E-value	Query Range	Subject Range
gi\|114619695, gi... - gi\|114619695\|ref\|XP_001170375.1\| PREDICTED: steroidogenic acute regulator isoform 6 [Pan troglodytes...	2.0E-93	[1..285]	[1..285]
gi\|61370498, gi\|... - gi\|61370505\|gb\|AAX43506.1\| steroidogenic acute regulator [synthetic construct], gi\|61370498\|gb\|AAX43...	4.0E-93	[1..285]	[1..285]
STAR - steroidogenic acute regulatory protein	6.0E-93	[1..285]	[1..285]
gi\|109086164 - gi\|109086164\|ref\|XP_001090472.1\| PREDICTED: similar to steroidogenic acute regulator isoform 1 isofo...	1.0E-91	[1..285]	[1..285]
gi\|57097785 - gi\|57097785\|ref\|XP_532807.1\| PREDICTED: similar to steroidogenic acute regulator isoform 1 [Canis fa...	5.0E-91	[1..285]	[1..285]
gi\|56711334, gi\|... - gi\|56711334\|ref\|NP_998920.2\| steroidogenic acute regulatory protein [Sus scrofa], gi\|56112364\|gb\|AAV...	5.0E-91	[1..285]	[1..285]
STAR_HORSE - Steroidogenic acute regulatory protein, mitochondrial OS=Equus caballus GN=STAR PE=2 SV=1	9.0E-91	[1..285]	[1..285]
STAR_BOVIN - Steroidogenic acute regulatory protein, mitochondrial OS=Bos taurus GN=STAR PE=1 SV=2	3.0E-90	[1..285]	[1..285]

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Predicted Domain #1

Region A:
Residues: [1-285]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLLATFKLCA GSSYRHMRNM KGLRQQAVMA ISQELNRRAL GGPTPSTWIN QVRRRSSLLG  60
   61 SRLEETLYSD QELAYLQQGE EAMQKALGIL SNQEGWKKES QQDNGDKVMS KVVPDVGKVF 120
  121 RLEVVVDQPM ERLYEELVER MEAMGEWNPN VKEIKVLQKI GKDTFITHEL AAEAAGNLVG 180
  181 PRDFVSVRCA KRRGSTCVLA GMATDFGNMP EQKGVIRAEH GPTCMVLHPL AGSPSKTKLT 240
  241 WLLSIDLKGW LPKSIINQVL SQTQVDFANH LRKRLESHPA SEARC

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	50.0
Match:	1em2A
Description:	Lipid transport domain of Mln64
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
binding	1.60389066490451	bayes_pls_golite062009
protein binding	1.48975086203348	bayes_pls_golite062009
sterol binding	0.63856471069172	bayes_pls_golite062009
SH2 domain binding	0.434779463822261	bayes_pls_golite062009
cholesterol binding	0.432520187215906	bayes_pls_golite062009
phospholipid transporter activity	0.328500953276889	bayes_pls_golite062009
lipid binding	0.207466011012419	bayes_pls_golite062009
lipid transporter activity	0.166184613717813	bayes_pls_golite062009
steroid binding	0.109277325408336	bayes_pls_golite062009
catalytic activity	0.0116392906163881	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: