YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|4151070, gi\|1...
Organism:	Plasmodium falciparum
Length:	470 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|4151070, gi|1....

Description	E-value	Query Range	Subject Range
gi\|23485755 - gi\|23485755\|gb\|EAA20557.1\| glutamate dehydrogenase [Plasmodium yoelii yoelii] gi\|82915173 - gi\|82915173\|ref\|XP_728992.1\| glutamate dehydrogenase [Plasmodium yoelii yoelii str. 17XNL]	534.0	[0..5]	[468..739]
gi\|56499621 - gi\|56499621\|emb\|CAH96328.1\| glutamate dehydrogenase, putative [Plasmodium berghei] gi\|68074157 - gi\|68074157\|ref\|XP_678993.1\| glutamate dehydrogenase [Plasmodium berghei strain ANKA]	533.0	[0..2]	[468..13]
gi\|56523292 - gi\|56523292\|emb\|CAH79883.1\| glutamate dehydrogenase, putative [Plasmodium chabaudi chabaudi] gi\|70948291 - gi\|70948291\|ref\|XP_743678.1\| glutamate dehydrogenase [Plasmodium chabaudi chabaudi]	528.0	[0..8]	[468..2]
gi\|23497354, gi\|... - gi\|23509508\|ref\|NP_702175.1\| glutamate dehydrogenase, putative [Plasmodium falciparum 3D7], gi\|23497...	525.0	[0..3]	[468..44]
gi\|86131236, gi\|... - gi\|86131236\|ref\|ZP_01049835.1\| glutamate dehydrogenase [Cellulophaga sp. MED134], gi\|85818647\|gb\|EAQ...	520.0	[0..25]	[469..1]
gi\|107099749 - gi\|107099749\|ref\|ZP_01363667.1\| hypothetical protein PaerPA_01000767 [Pseudomonas aeruginosa PACS2] gi\|254238668, gi... - gi\|84317187\|ref\|ZP_00965641.1\| COG0334: Glutamate dehydrogenase/leucine dehydrogenase [Pseudomonas a...	518.0	[0..25]	[469..1]
gi\|11348602 - pir\|\|H83072 glutamate dehydrogenase PA4588 [imported] - Pseudomonas aeruginosa (strain PAO1) gi\|46165034, gi\|... - gi\|46165034\|ref\|ZP_00138144.2\| COG0334: Glutamate dehydrogenase/leucine dehydrogenase [Pseudomonas a... gi\|218773911, gi... - gi\|218893683\|ref\|YP_002442552.1\| glutamate dehydrogenase [Pseudomonas aeruginosa LESB58], gi\|2187739... gi\|15599784, gi\|... - gi\|9950836\|gb\|AAG07976.1\|AE004872_7 glutamate dehydrogenase [Pseudomonas aeruginosa PAO1], gi\|155997... gi\|84323381, gi\|... - gi\|84323381\|ref\|ZP_00971454.1\| COG0334: Glutamate dehydrogenase/leucine dehydrogenase [Pseudomonas a...	517.0	[0..25]	[469..1]
gi\|89889970, gi\|... - gi\|89889970\|ref\|ZP_01201481.1\| NAD(P)-specific glutamate dehydrogenase [Flavobacteria bacterium BBFL...	517.0	[0..25]	[469..1]

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Predicted Domain #1

Region A:
Residues: [1-470]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSALKDKTGR FVVLDKNASN YESLVDQEMN NVYERVMKLD PNQVEFLQAF HEILYSLKPL  60
   61 FMEEPKYLPI IETLSEPERA IQFRVCWLDD NGVQRKNRCF RVQYNSALGP YKGGLRFHPS 120
  121 VNLSIVKFLG FEQIFKNSLT GLSMGGGKGG SDFDPKGKSD NEILKFCQAF MNELYRHIGP 180
  181 CTDVPAGDIG VGGREIGYLY GQYKKIVNSF NGTLTGKNVK WGGSNLRVEA TGYGLVYFVL 240
  241 EVLKSLNIPV EKQTAVVSGS GNVALYCVQK LLHLNVKVLT LSDSNGYVYE PNGFTHENLE 300
  301 FLIDLKEEKK GRIKEYLNHS STAKYFPNEK PWGVPCTLAF PCATQNEINL EDAKLLQKNG 360
  361 CILVGEGANM PSTVDAINLF KSNNIIYCPS KAANAGGVAI SGLEMSQNFQ FSHWTRETVD 420
  421 EKLKEIMRNI FIACSENALK YTKNKYDLQA GANIAGFLKV AESYIEQGCF

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	145.0
Match:	2bmaA
Description:	The crystal structure of Plasmodium falciparum glutamate dehydrogenase, a putative target for novel antimalarial drugs
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits