YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|7494402
Organism:	Plasmodium falciparum
Length:	904 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|7494402.

Description	E-value	Query Range	Subject Range
gi\|11999114 - gi\|11999114\|gb\|AAG43050.1\|AF139827_1 replication factor C subunit 1 [Plasmodium falciparum]	415.0	[0..1]	[904..1]
gi\|27361197, gi\|... - gi\|27365051\|ref\|NP_760579.1\| ATP-dependent Zn protease [Vibrio vulnificus CMCP6], gi\|27361197\|gb\|AAO...	350.0	[0..286]	[853..76]
gi\|17428542 - gi\|17428542\|emb\|CAD15228.1\| probable atp-dependent zinc metallopeptidase (cell division ftsh) transm... gi\|17546245 - gi\|17546245\|ref\|NP_519647.1\| ATP-dependent zinc metallopeptidase [Ralstonia solanacearum GMI1000]	350.0	[0..330]	[788..121]
gi\|37680899, gi\|... - gi\|37680899\|ref\|NP_935508.1\| ATP-dependent Zn protease [Vibrio vulnificus YJ016], gi\|37199649\|dbj\|BA...	350.0	[0..286]	[853..79]
gi\|89348478, gi\|... - gi\|89362683\|ref\|ZP_01200487.1\| Peptidase M41, FtsH [Xanthobacter autotrophicus Py2], gi\|89348478\|gb\|...	349.0	[0..330]	[797..124]
gi\|121607214, gi... - gi\|121607214\|ref\|YP_995021.1\| ATP-dependent metalloprotease FtsH [Verminephrobacter eiseniae EF01-2]...	348.0	[0..290]	[789..104]
gi\|89345533, gi\|... - gi\|89900796\|ref\|YP_523267.1\| ATP-dependent metalloprotease FtsH [Rhodoferax ferrireducens T118], gi\|...	348.0	[0..290]	[789..88]
gi\|207742906, gi... - gi\|207742906\|ref\|YP_002259298.1\| atp-dependent zinc metallopeptidase (cell division protein ftsh) [R... gi\|83747762, gi\|... - gi\|83747762\|ref\|ZP_00944796.1\| Cell division protein ftsH [Ralstonia solanacearum UW551], gi\|8372553... gi\|207723996, gi... - gi\|207723996\|ref\|YP_002254394.1\| atp-dependent zinc metallopeptidase (cell division protein ftsh) [R...	347.0	[0..330]	[788..121]
FTSH_PHOPR - ATP-dependent zinc metalloprotease FtsH OS=Photobacterium profundum GN=ftsH PE=3 SV=1 FTSH_PHOPR - ATP-dependent zinc metalloprotease FtsH OS=Photobacterium profundum (strain SS9) GN=ftsH PE=3 SV=1	346.0	[0..249]	[865..64]
gi\|187477434, gi... - gi\|187477434\|ref\|YP_785458.1\| cell division protein [Bordetella avium 197N], gi\|115422020\|emb\|CAJ485...	345.0	[0..287]	[779..78]

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Predicted Domain #1

Region A:
Residues: [1-656]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSKDKNLFS DDESDDGRKK KRLKKVSSSL FHDDDDDNFI SNKKVEKSKS KKKSDAIYID  60
   61 DNESNNNNNY NNTNKSSNRK SLENKSSKTS PKFYDITSFF KPSSKKLEDN NTMKKSNSKE 120
  121 DEKLVVNNLN DYFNILQNDN KVTKEDTKSN NVSPKNEINK SNVKRERESE QYEISSENDT 180
  181 VSSKKNVLIS PAKKQKTQNN NNEDLQKFDY LPFHNQKFVI TGVFKNFTRD ELQSKIKEHG 240
  241 GSVMTAVSTK TNYLVHGEYL EDGRLFNEGR KYTKAFELQQ QNKSNIKILN EEELLKLLPQ 300
  301 TDQTQENDKT YASDTIKTEN KDKNYNYEKK DKNYNYEKKD THNTQNEILN QLWVEKYRPK 360
  361 NLNELVGNNQ NVIKLQNWLA SWEDVCIKGI KKPAQKTFRG IFENVNARCA LLSGPAGIGK 420
  421 TTTAKIVSEA SGYNVIEFNA SDERNKAAVE KISEMATGGY SIMSLNNRKL TKTCIIMDEV 480
  481 DGMSSGDKGG STAILKLIEK TKCPIICICN DRQNNKMRTL ANKCYDLKFS MPQKNSVVKR 540
  541 LLEICKKEGI MMEPNALELL WESTCGDIRQ MLNTLQLLSK TYTRIQFLDL KKELNNSNKN 600
  601 IQSLANPFEI TLKLLNFNES SKLNIREIMD LFFVDYELIP YFISENYTNV FNETDK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	79.0
Match:	1oz4A
Description:	VCP/p97
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [657-752]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SSASLNKWNV FSQIAHDLSL ADKIKYNMKS NMDFALLPHF AILSCVCPVM RIKILKSFMS  60
   61 GRVNFPTAFG KISTFNKNKR LLNELCFNLS YKLNVC

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	45.045757
Match:	1sxjA
Description:	Crystal Structure of the Eukaryotic Clamp Loader (Replication Factor C, RFC) Bound to the DNA Sliding Clamp (Proliferating Cell Nuclear Antigen, PCNA)
Matching Structure (courtesy of the PDB):

Predicted Domain #3

Region A:
Residues: [753-904]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PKYMVTSGFL NYIYFKIMTP LHKADVNQAI QIMEEYSITR EMVTENLPCL RLPNQENLYD  60
   61 KLDTKLKSSF TRLYNSSHVI KIDPNSMKKG LKSSEKKTTF KLNEFESDED IDELSESKED 120
  121 KDDDVLIKTK IDRKGTLKTK PSTKVKSMKK AK

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	3.14
Match:	1sxjA
Description:	Crystal Structure of the Eukaryotic Clamp Loader (Replication Factor C, RFC) Bound to the DNA Sliding Clamp (Proliferating Cell Nuclear Antigen, PCNA)
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits