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View Structure Prediction Details

Protein: gi|7494151
Organism: Plasmodium falciparum
Length: 888 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|7494151.

Description E-value Query
Range
Subject
Range
gi|75701558, gi|... - gi|75907833|ref|YP_322129.1| amino acid adenylation [Anabaena variabilis ATCC 29413], gi|75701558|gb...
511.0 [0..8] [884..399]
gi|27817223 - gi|27817223|gb|AAO23334.1| NcpB [Nostoc sp. ATCC 53789]
507.0 [0..9] [886..1439]
gi|28804618 - gi|28804618|dbj|BAC57997.1| microcystin synthetase [Microcystis viridis NIES-102]
gi|28804618 - gi|28804618|dbj|BAC57997.1| microcystin synthetase [Microcystis viridis]
500.0 [0..100] [888..2]
gi|9715733 - gi|9715733|emb|CAC01603.1| peptide synthetase [Anabaena circinalis 90]
494.0 [0..129] [857..544]
gi|186682529, gi... - gi|23129063|ref|ZP_00110897.1| COG1020: Non-ribosomal peptide synthetase modules and related protein...
492.0 [0..8] [874..1425]
gi|14486359 - gi|14486359|gb|AAK61391.1| microcystin synthetase [Microcystis aeruginosa]
491.0 [0..24] [888..357]
gi|6563397 - gi|6563397|gb|AAF15891.2|AF204805_1 NosA [Nostoc sp. GSV224]
487.0 [0..8] [877..1419]

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Predicted Domain #1
Region A:
Residues: [1-699]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MHIIFSVCLF IIYIIHVYPC KSGCLGKDKG YSEICEKAIY ENESNTFCMK DHLIRESLFI  60
   61 YKPIMKLLLK KYRLRNNKIA IVEHAYGEPQ NFITYGKFFR KVLSFSHSLN NFEGQGIQGK 120
  121 SYKEHQNHGW FRLLGIYGSN SINWLIVDMA AMMSGVTTLI LHSNFSIDVI VNILNETKLE 180
  181 WLCLDLDLVD GLLLHRHELP YLKKLIILDN LVKPIRIDIL RYVFNNENNV SEYDDASDDD 240
  241 ENSESSDESF EINMGLAEYD VEKLEKIKDL KERSKNVGIR FLEFDDVSSV PTKIYNIQND 300
  301 EPDFITSIVY TSGTSGKPKG VMLSNLNMYN AIVPLCKHSM LNYHPKAHLS YLPVSHIYER 360
  361 VNVYVAFLSG IKIDIWSKNI NFFSRDIFNS KGELLVGVPK VFNRIYSNIM AEINNLSATK 420
  421 RRNIKNVFSL RRSVNCACFT NLLEGLTGYS SKIRNCVNPN LEVILNGGGK LSPRIAEELR 480
  481 VLLNVNFYQG YGLTETTGPI FVQQKRDYNT ESIGGPIAPN TKYKVRTWET YKASDSTPKG 540
  541 ELLIKSDSIF KGYFLERELT ENSFTYDHFF VTGDIVQIND NGSLTFLDRS KGLVKLSQGE 600
  601 YIETDLLNNI YSEIPFINNC VVYGDDSLDE ALAIISVDKY LLFRCLRDDN MLNETGINEK 660
  661 NYMDKLSDQN INTKHFIDYV KNKMLEVYNN TNLNRYNII

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 103.0
Match: 1pg3A
Description: Acetyl-CoA synthetase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
catalytic activity 1.30539319136328 bayes_pls_golite062009
ligase activity 0.20580854487081 bayes_pls_golite062009
ligase activity, forming carbon-sulfur bonds 0.0874529293560995 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [700-776]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NHIYLTSKTW DTTNYLTPTM KVKRFSVIQD YAFFIDQVKN IFKKKLKGQK ERTKRLQKKT  60
   61 SDEQEIKNDE NDQEKSK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 5.0
Match: 2gdwA
Description: No description for 2gdwA was found.

Predicted Domain #3
Region A:
Residues: [777-888]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KSYFSRLSQK RKSRSQEKNK STSQEKNKST SQEKNKSKSK EKNTSTLPQD NISIPVQNKI  60
   61 EKPQQNNMSN ITLKNTLKST DASLKIPEKN KVQTNKSRFQ VQNVREELEM NS

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle