YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|7494150
Organism:	Plasmodium falciparum
Length:	885 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|7494150.

Description	E-value	Query Range	Subject Range
gi\|12240281 - gi\|12240281\|gb\|AAG49599.1\|AF326974_1 long chain fatty acyl CoA synthetase; fatty acid CoA ligase [No...	424.0	[0..303]	[883..113]
gi\|55728677 - gi\|55728677\|emb\|CAH91078.1\| hypothetical protein [Pongo abelii] gi\|197098952 - gi\|197098952\|ref\|NP_001125625.1\| acyl-CoA synthetase long-chain family member 1 [Pongo abelii]	424.0	[0..303]	[883..113]
gi\|23573636 - gi\|23573636\|gb\|AAN38753.1\| long chain fatty acyl CoA synthetase [Notothenia angustata]	423.0	[0..303]	[883..113]
gi\|73979490 - gi\|73979490\|ref\|XP_848838.1\| PREDICTED: similar to acyl-CoA synthetase long-chain family member 1 is...	423.0	[0..303]	[883..113]
gi\|23573638 - gi\|23573638\|gb\|AAN38754.1\| long chain fatty acyl CoA synthetase [Eleginops maclovinus]	422.0	[0..303]	[883..113]
gi\|116241239 - gi\|116241239\|sp\|Q9UKU0\|ACSL6_HUMAN Long-chain-fatty-acid--CoA ligase 6 (Long-chain acyl-CoA syntheta...	421.0	[0..310]	[881..123]
gi\|76655661, gi\|... - gi\|76655661\|ref\|XP_881290.1\| PREDICTED: similar to acyl-CoA synthetase long-chain family member 1 is...	420.0	[0..303]	[883..114]

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Predicted Domain #1

Region A:
Residues: [1-225]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLIYNFFIVL IYIFQTASYY TKSLTGSSYS EIYSKSLSDD ESDTYQGKDY DNKSPYYIYS  60
   61 HLLKIIIKKN KFNGDKKLIY EYANGHPKSS YTYDTFFNRV LSFSDGLNTY EGTGIQVKKY 120
  121 NEEQNNGMFR LLGLYGSNSA NWITADISCM LSGVTTVVMH SKFILNEIVD ILNEVKLEWL 180
  181 CLDLDFVENL LYLKSSLPHL KKLIILDTFI NPSICNRKGG KSKNG

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	2.87
Match:	1ry2A
Description:	Crystal structure of yeast acetyl-coenzyme A synthetase in complex with AMP
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [226-885]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DEGQAVGNNG EKEEKEEHKG EAEEDDEDGE DDEDDEDDED GEDDEDDEDG EDGEDDEDDE  60
   61 DGEDGEDDDD DEKGDNIKDD YLYKKQNEIP NENIVEEQGE GEDQRNVHQT VQPTPYGANT 120
  121 KQYLKKKKKK RTENVEERKK SNMKRKESKW IKKHMYPKLI YENIDLEDIC EDEKKKIEKL 180
  181 KYLKEEAKKY GIQIIQFNEM LINKNNNMLT YNIQNDKENF ISTIVYTSGT SGRPKGVMLS 240
  241 NKNIYYMVIP LSKHSIFTYN VDTHLSYLPL SHIYERINIY LCFVLTVEIH IWSKNLKYFS 300
  301 SDILVSKSSF LAGVPKVFNR IYNNVITEIG KLPFLKKFFV EKILSLKRSN MNGKFSKFIE 360
  361 AITNISKKIR SKINPNLNTF ITGGGKTSPK VISELSLLLN VSIQQGYGLT ETTGPLFVQH 420
  421 RKDKDPESTG GPISPHVLYK VQSWEIYNAK DSLPRGELLI KGDCIFHGYF VHKDITDNSF 480
  481 TEDKFFKTGD IVQINKNGSL TFLDRSKGLL KLAQGEYIQT DMLNSLYSEI PFINHCVVYA 540
  541 DDTLSGPIAV VSIDKELFIK HLLEDNIISD VGTVEEEFLE AIDDEQINSD VYVNYVKQKM 600
  601 LEAYKKTNLN GYNIINHIYL TVKVWDISNY ITPTFKIKRF HVFRDYAFFI DDIKKLYSSK 660
  661

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	97.69897
Match:	2p2bA
Description:	No description for 2p2bA was found.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits