YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|25510657
Organism:	Yersinia pestis
Length:	436 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|25510657.

Description	E-value	Query Range	Subject Range
gi\|67668083, gi\|... - gi\|67668083\|ref\|ZP_00465278.1\| General substrate transporter:Major facilitator superfamily [Burkhold...	1.0E-55	[3..434]	[1019..1471]
gi\|60467752, gi\|... - gi\|60467752\|gb\|EAL65769.1\| hypothetical protein DDB0191430 [Dictyostelium discoideum], gi\|29500764\|g... gi\|60467752, gi\|... - gi\|66810832\|ref\|XP_639123.1\| major facilitator superfamily transporter [Dictyostelium discoideum AX4...	8.0E-47	[21..403]	[595..1015]
gi\|78495751, gi\|... - gi\|78495751\|ref\|ZP_00847969.1\| Major facilitator superfamily MFS_1 [Rhodopseudomonas palustris BisB1...	4.0E-45	[1..436]	[424..862]
gi\|169764102 - gi\|169764102\|ref\|XP_001727951.1\| hypothetical protein [Aspergillus oryzae RIB40] gi\|83770979 - gi\|83770979\|dbj\|BAE61112.1\| unnamed protein product [Aspergillus oryzae]	5.0E-44	[8..434]	[193..645]
SNF3 - Plasma membrane low glucose sensor that regulates glucose transport; contains 12 predicted transmemb... SNF3_YEAST - High-affinity glucose transporter SNF3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=S...	2.0E-43	[1..434]	[67..546]
gi\|110827356, gi... - gi\|111615223\|ref\|ZP_01402289.1\| Sugar phosphate permease-like [Verminephrobacter eiseniae EF01-2], g...	3.0E-42	[23..434]	[297..694]
gi\|85110133 - gi\|85110133\|ref\|XP_963279.1\| hypothetical protein [Neurospora crassa OR74A] gi\|28924953, gi\|... - gi\|32417950\|ref\|XP_329453.1\| hypothetical protein [Neurospora crassa], gi\|28924953\|gb\|EAA34043.1\| hy...	3.0E-41	[5..425]	[360..787]
gi\|55238369, gi\|... - gi\|58387445\|ref\|XP_315568.2\| ENSANGP00000022770 [Anopheles gambiae str. PEST], gi\|55238369\|gb\|EAA440...	7.0E-41	[15..435]	[198..641]
gi\|52005333, gi\|... - gi\|52787512\|ref\|YP_093341.1\| YwtG [Bacillus licheniformis ATCC 14580], gi\|52350014\|gb\|AAU42648.1\| Yw...	7.0E-40	[23..435]	[4..431]

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Predicted Domain #1

Region A:
Residues: [1-436]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSESSTESLS QPTQLQEENN AYRKTVWHLL PLLMLCYVLN YLDRVNVGFA KLQMADDLQF  60
   61 SDTVYGLGAG MFFIGYFFLE IPSNLILHRV GARLWIARIM ITWGIISACM AFVTTPMSFY 120
  121 VMRFLLGVAE AGFFPGIILY ISYWFPSHRR GRVYGLFVIS VPLSGIIGAP LSGWIMQYFN 180
  181 GFQGYAGWQW MFILEGIPSV LVGILIIYKL KDRITHATWL TDKEKDILQT NIENEAAHYA 240
  241 HSRLRDAFLQ PRVWLLTLIY FCLISGFYTI GFWLPTLIRD SGVKDILSIG FLTAIPSAAA 300
  301 AVTMIVVSRS ADRLRERRWH LALTAVLGAV GIILSTYFSD NIVVAMVCLT IGAMGALSTI 360
  361 PLFWSLPTAF LGGSAAAAGI AFINSWGNLG GFVAPYMMGY LKDLTQSTTT GMLIISTTLF 420
  421 IGAALVFLIP AKAVNH

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	29.0
Match:	1pw4A
Description:	Crystal Structure of the Glycerol-3-Phosphate Transporter from E.Coli
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
transporter activity	4.09176719149278	bayes_pls_golite062009
transmembrane transporter activity	3.5865018981083	bayes_pls_golite062009
substrate-specific transporter activity	3.3426261924492	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	3.29689809004391	bayes_pls_golite062009
organic acid transmembrane transporter activity	2.15783210522667	bayes_pls_golite062009
ion transmembrane transporter activity	1.94035843948137	bayes_pls_golite062009
active transmembrane transporter activity	1.59419818573076	bayes_pls_golite062009
cation transmembrane transporter activity	1.5181741634556	bayes_pls_golite062009
secondary active transmembrane transporter activity	1.22264637452409	bayes_pls_golite062009
polyol transmembrane transporter activity	0.924836669821548	bayes_pls_golite062009
alcohol transmembrane transporter activity	0.924836669821548	bayes_pls_golite062009
glycerol transmembrane transporter activity	0.812001619402678	bayes_pls_golite062009
binding	0.805286077372817	bayes_pls_golite062009
symporter activity	0.74591237387473	bayes_pls_golite062009
solute:cation symporter activity	0.74591237387473	bayes_pls_golite062009
cation:sugar symporter activity	0.143419068761182	bayes_pls_golite062009
sugar:hydrogen symporter activity	0.143419068761182	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: