YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|25283924
Organism:	Yersinia pestis
Length:	413 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|25283924.

Description	E-value	Query Range	Subject Range
gi\|37199786, gi\|... - gi\|37681036\|ref\|NP_935645.1\| D-3-phosphoglycerate dehydrogenase [Vibrio vulnificus YJ016], gi\|371997...	0.0	[1..413]	[1..409]
gi\|27361062, gi\|... - gi\|27364916\|ref\|NP_760444.1\| D-3-phosphoglycerate dehydrogenase [Vibrio vulnificus CMCP6], gi\|273610...	0.0	[1..413]	[1..409]
gi\|28899367, gi\|... - gi\|28899367\|ref\|NP_798972.1\| D-3-phosphoglycerate dehydrogenase [Vibrio parahaemolyticus RIMD 221063... gi\|28807603 - gi\|28807603\|dbj\|BAC60856.1\| D-3-phosphoglycerate dehydrogenase [Vibrio parahaemolyticus RIMD 2210633...	0.0	[1..413]	[1..410]
gi\|75853741, gi\|... - gi\|75853741\|ref\|ZP_00761512.1\| COG0111: Phosphoglycerate dehydrogenase and related dehydrogenases [V...	0.0	[1..413]	[1..410]
gi\|71555670, gi\|... - gi\|71735117\|ref\|YP_276976.1\| D-3-phosphoglycerate dehydrogenase [Pseudomonas syringae pv. phaseolico...	0.0	[1..413]	[21..429]
gi\|22127177, gi\|... - gi\|22127177\|ref\|NP_670600.1\| D-3-phosphoglycerate dehydrogenase [Yersinia pestis KIM], gi\|21960241\|g... gi\|45438214, gi\|... - gi\|45443345\|ref\|NP_994884.1\| D-3-phosphoglycerate dehydrogenase [Yersinia pestis biovar Microtus str...	0.0	[1..413]	[35..447]
gi\|112822311, gi... - gi\|113460268\|ref\|YP_718326.1\| D-3-phosphoglycerate dehydrogenase [Haemophilus somnus 129PT], gi\|1128...	0.0	[2..413]	[3..410]
gi\|53728366, gi\|... - gi\|53728366\|ref\|ZP_00133076.2\| COG0111: Phosphoglycerate dehydrogenase and related dehydrogenases [H...	0.0	[2..413]	[3..410]
gi\|68249067, gi\|... - gi\|68249067\|ref\|YP_248179.1\| D-3-phosphoglycerate dehydrogenase [Haemophilus influenzae 86-028NP], g...	0.0	[1..413]	[1..410]
gi\|77953234, gi\|... - gi\|77953234\|ref\|ZP_00817644.1\| D-3-phosphoglycerate dehydrogenase [Marinobacter aquaeolei VT8], gi\|7...	0.0	[1..413]	[31..439]

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Predicted Domain #1

Region A:
Residues: [1-413]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAKVSLEKDR IKFLLVEGVH QSAVDNLRAA GYSNIEYHKG ALDAESLKAS IRDAHFIGIR  60
   61 SRTHLSEDVF AAAEKLVAVG CFCIGTNQVD LKAATKRGVP VFNAPFSNTR SVAEMVLGEL 120
  121 LLMFRGIPSA NAKAHRGEWN KLAVGSFEAR GKKLGIIGYG HIGTQLGILA ESIGMKVFFY 180
  181 DIENKLSLGN AQQVRQLSDL LNMSDVVSLH VPENHTTKNM IGAEQLAQMK PGALLINASR 240
  241 GTVVDIPALC DALSSNHLSG AAIDVFPEEP ATNKDPFNSP LCEFDNVLLT PHIGGSTQEA 300
  301 QENIGDEVAG KLAKYSDNGS TLSAVNFPEV SLPAHGDNTR RLLHIHENRP GILTSINTIF 360
  361 AEQNVNIAAQ YLQTSADIGY VVIDVETDDA DNAEKALQAM KAIPGTIRAR LLY

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	107.0
Match:	1ybaA
Description:	The active form of phosphoglycerate dehydrogenase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
acetolactate synthase activity	3.48670706716817	bayes_pls_golite062009
transferase activity, transferring aldehyde or ketonic groups	2.1980358206838	bayes_pls_golite062009
catalytic activity	1.79741889688267	bayes_pls_golite062009
oxidoreductase activity	1.69771604880532	bayes_pls_golite062009
alcohol dehydrogenase (NAD) activity	1.68027744358887	bayes_pls_golite062009
alcohol dehydrogenase activity, zinc-dependent	0.839863523675468	bayes_pls_golite062009
phosphoglycerate dehydrogenase activity	0.639509916626856	bayes_pls_golite062009
oxidoreductase activity, acting on CH-OH group of donors	0.418775403210681	bayes_pls_golite062009
binding	0.355184540089764	bayes_pls_golite062009
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	0.32207755075663	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: