YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|25509696
Organism:	Yersinia pestis
Length:	425 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|25509696.

Description	E-value	Query Range	Subject Range
gi\|148262949, gi... - gi\|88936481\|ref\|ZP_01142089.1\| PAS:GGDEF [Geobacter uraniumreducens Rf4], gi\|88916750\|gb\|EAR35961.1\|...	4.0E-72	[108..424]	[133..444]
gi\|145600440, gi... - gi\|145600440\|ref\|YP_001164516.1\| hypothetical protein YPDSF_3185 [Yersinia pestis Pestoides F], gi\|1... gi\|162419428, gi... - gi\|162419428\|ref\|YP_001605395.1\| GGDEF domain-containing protein [Yersinia pestis Angola], gi\|162352... gi\|165920781, gi... - gi\|165927319\|ref\|ZP_02223151.1\| putative diguanylate cyclase, GGDEF domain [Yersinia pestis biovar O... gi\|165936365, gi... - gi\|165936365\|ref\|ZP_02224933.1\| putative diguanylate cyclase, GGDEF domain [Yersinia pestis biovar O... gi\|229696699, gi... - gi\|229840333\|ref\|ZP_04460492.1\| putative exported protein [Yersinia pestis biovar Orientalis str. PE... gi\|166008970, gi... - gi\|166008970\|ref\|ZP_02229868.1\| putative diguanylate cyclase, GGDEF domain [Yersinia pestis biovar A... gi\|229842413, gi... - gi\|229842413\|ref\|ZP_04462568.1\| putative exported protein [Yersinia pestis biovar Orientalis str. In... gi\|166206882, gi... - gi\|166212136\|ref\|ZP_02238171.1\| putative diguanylate cyclase, GGDEF domain [Yersinia pestis biovar A... gi\|108810030, gi... - gi\|108810030\|ref\|YP_653946.1\| hypothetical protein YPA_4040 [Yersinia pestis Antiqua], gi\|108781943\|... gi\|167401527, gi... - gi\|167401527\|ref\|ZP_02307021.1\| putative diguanylate cyclase, GGDEF domain [Yersinia pestis biovar A... gi\|167418912, gi... - gi\|167418912\|ref\|ZP_02310665.1\| putative diguanylate cyclase, GGDEF domain [Yersinia pestis biovar O... gi\|167468844 - gi\|167468844\|ref\|ZP_02333548.1\| putative diguanylate cyclase, GGDEF domain [Yersinia pestis FV-1] gi\|186893943, gi... - gi\|186893943\|ref\|YP_001871055.1\| diguanylate cyclase [Yersinia pseudotuberculosis PB1/+], gi\|1866969... gi\|229705914, gi... - gi\|229836971\|ref\|ZP_04457136.1\| putative exported protein [Yersinia pestis Pestoides A], gi\|22970591...	4.0E-72	[1..425]	[9..433]
gi\|88858416, gi\|... - gi\|88858416\|ref\|ZP_01133058.1\| hypothetical protein PTD2_13539 [Pseudoalteromonas tunicata D2], gi\|8...	5.0E-71	[96..424]	[253..581]
gi\|78363780, gi\|... - gi\|78485494\|ref\|YP_391419.1\| diguanylate cyclase/phosphodiesterase [Thiomicrospira crunogena XCL-2],...	5.0E-71	[122..422]	[910..1209]
gi\|71147827, gi\|... - gi\|71282087\|ref\|YP_269787.1\| sensory box protein [Colwellia psychrerythraea 34H], gi\|71147827\|gb\|AAZ...	6.0E-71	[43..423]	[232..593]
gi\|95133648, gi\|... - gi\|95930396\|ref\|ZP_01313133.1\| diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s) [Desulfu...	6.0E-70	[46..424]	[275..653]
gi\|221563411, gi... - gi\|222054122\|ref\|YP_002536484.1\| response regulator receiver modulated diguanylate cyclase/phosphodi...	3.0E-69	[112..424]	[131..444]
gi\|83310313, gi\|... - gi\|83310313\|ref\|YP_420577.1\| signal transduction protein [Magnetospirillum magneticum AMB-1], gi\|829...	2.0E-68	[96..424]	[287..615]
gi\|77976247 - gi\|77976247\|ref\|ZP_00831754.1\| COG2199: FOG: GGDEF domain [Yersinia intermedia ATCC 29909]	8.0E-68	[6..404]	[14..412]

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Predicted Domain #1

Region A:
Residues: [1-425]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKPKKNHNSA EKLPTLAGVL RRIHLSVAIV SVVTACIFLT VAALFALRVY VDHNLHLIAR  60
   61 AISYTTEAAV VFGDNVEANE LLALIASNEE VAEAKIIDKH NRQIAYWALP DDGPIHHMEQ 120
  121 IVARWILPAP VVLPMFHAGD EIGKIVIVGH GGSLLRFLLQ GLAGMLACLT VSTLVALFLS 180
  181 RRMLLGIVGS LKRITEVAHN VSRHRSFGQR VPSAKVAELN ELSNDFNGLL EELEVWQKHL 240
  241 TQENDSLAYR AAHDSLTGLA NRTFFEGRLS RTLNDCQPGE HTAVLFLDGD HFKDVNDNYG 300
  301 HAAGDLVLTT IAVRIRALLR ETDLVARLGG DEFAVLLTPI HNLDDVLTIA DHIIDSMALP 360
  361 IILAEGCEIT VSLSIGIAVY PDHAQTPEKL LQRADEAMYQ AKKNFRSGKR IFAYQPNTTN 420
  421 TESLG

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	36.045757
Match:	1w25A
Description:	Response regulator PleD in complex with c-diGMP
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits